Advances in Understanding Mechanisms and Treatment of Infantile Forms of Nystagmus

by Leigh, R. John; Devereaux, Michael W.

• ISBN13: 9780195342185
• ISBN10: 0195342186
• Edition: 1st
• Format: Hardcover
• Copyright: 2008-07-14
• Publisher: Oxford University Press

Summary

This volume brings together work from leading researchers in the fields of developmental disorders of binocular vision, strabismus, and both infantile and acquired forms of nystagmus. It contains four sections. The first section, Basic Concepts of Stable Vision and Gaze, deals with psychophysical aspects of infantile forms of nystagmus and the relative contributions of extraocular proprioception and efference (corollary discharge). It also contains an accessible review of current notions of spatial and temporal visual functions and spatial constancy in infantile nystagmus syndrome and latent nystagmus. The second section, New Models and Techniques for Studying Gaze Stability, reviews animal and development models for strabismus, amblyopia, and nystagmus. It also contains novel optical methods for managing the visual consequences of nystagmus and a study of the potential ill effects of video displays on children's response to near viewing. The third section, New Therapies for Congenital Nystagmus, presents basic genetic studies and clinical trials of drug and surgical treatment of those patients with infantile forms of nystagmus. The final section,General Aspects of Normal and Abnormal Gaze Control, pulls together a range of contributions dealing with normal gaze control, infantile nystagmus, and acquired disorders of eye movements, including new treatment measures. This book will be a valuable resource for all scientists and practitioners interested in developmental disorders of vision.

Table of Contents

Contributors	p. ix
Basic Concepts of Stable Vision and Gaze
Afferent and Efferent Contributions to Knowledge of Eye Position	p. 3
Perceptual Influences of the Extraretinal Signals for Normal Eye Movements and Infantile Nystagmus	p. 11
Perception with Unstable Fixation	p. 23
Internal and External Influences on Foveation and Perception in Infantile Nystagmus Syndrome	p. 33
Perceptual Fading during Voluntary and Involuntary Eye Movements	p. 42
New Models and Techniques for Studying Gaze Stability
Alternating Saccades in a Primate Model of Strabismus	p. 47
Effects of Cerebellar Lesions in Monkeys on Gaze Stability	p. 55
Development of Visual Stabilization Devices with Applications for Acquired and Infantile Nystagmus	p. 61
Pupil Abnormalities of the Near Response in Children with Visual Display Terminal Syndrome	p. 70
New Therapies for Congenital Nystagmus
Genetics and Pharmacological Treatment of Nystagmus: A Review of the Literature and Recent Findings	p. 79
New Treatments for Infantile and Other Forms of Nystagmus	p. 87
Clinical and Electrophysiological Effects of Extraocular Muscle Surgery on Fifty-three Patients with Infantile Periodic Alternating Nystagmus	p. 99
Eye Muscle Surgery for Acquired Forms of Nystagmus	p. 112
The Complement Hypothesis to Explain Preferential Involvement of Extraocular Muscle in Myasthenia Gravis	p. 117
General Aspects of Normal and Abnormal Gaze Control
Studies of the Ability to Hold the Eye in Eccentric Gaze: Measurements in Normal Subjects with the Head Erect	p. 129
Effect of Eye Exercise on Clinical Outcome of Noncompressive Ocular Motor Nerve Palsy	p. 136
Expanding the Original Behavioral Infantile Nystagmus Syndrome Model to Jerk Waveforms and Gaze-angle Variations	p. 139
Extension of the eXpanded Nystagmus Acuity Function to Vertical and Multiplanar Data	p. 143
Inertial and Noninertial Contributions to the Perception of Translation and Path	p. 14
The Effect of the Duncke Visual Illusion on Occluded Smooth-arm Tracking	p. 152
Posterior Internuclear Ophthalmoplegia of Lutz Revisited: Report of a Case Associated with a Midbrain Lesion	p. 156
Divergence Insufficiency Associated with Hereditary Spinocerebellar Ataxia	p. 162
Neuromuscular Junction Dysfunction in Miller Fisher Syndrome	p. 167
Involuntary Version-Vergence Nystagmus Induced by Ground-Plane Optic Flow: Analysis of Dynamic Characteristics of Nystagmus Quick Phases	p. 170
The Neuro-ophthalmologic Complications of Chiropractic Manipulation	p. 175
Vergence Hysteresis in Infantile Nystagmus	p. 180
Using Wavelet Analysis to Evaluate Effects of Eye and Head Movements on Ocular Oscillations	p. 184
Multifocal Electroretinographic Study of Patients with Oculocutaneous Albinism and Infantile Nystagmus Syndrome	p. 189
Author Index	p. 193
Subject Index	p. 204
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