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The social sciences, demography, and epidemiology have faced a long-standing problem of analysis of data in which events or outcome variables can be simultaneously affected by time periods (P) in which they occur as well as by the ages (A) and birth cohorts (C) or dates of origin of individuals or other units to which they occur. This book uses the GLMM approach to bring APC analysis to the twenty-first century of statistical practice. Written to accommodate readers less sophisticated in statistical modeling, this book presents a variety of empirical applications and interdisciplinary topics.