Antibiotic Basics for Clinicians The ABCs of Choosing the Right Antibacterial Agent

by Hauser, Alan R.

• ISBN13: 9781451112214
• ISBN10: 1451112211
• Edition: 2nd
• Format: Paperback
• Copyright: 2012-03-17
• Publisher: LWW

Summary

Designed for quick, easy comprehension, this handbook reference will assist students in nurse practitioner, physician assistant, and pharmacy programs and medical students in understanding the rationale behind antibiotic selection for common bacterial pathogens and infectious disease presentations. By supplying the rationale for choosing antibiotics, the book reduces the amount of memorization necessary for proper antibiotic prescribing or recommending antimicrobial agents. The book is heavily illustrated with two-color figures and includes boxed features, mnemonics, and review questions. Appendices include dosing in adults and children; antibacterial agents in pregnancy; generic and trade names of commonly used antibacterial agents; and treatment of infections caused by bacterial agents of bioterrorism.

Table of Contents

Preface	p. vii
Bacterial Basics	p. 1
Cell Envelope	p. 3
Protein Production	p. 6
Reproduction	p. 9
Measuring Susceptibility to Antibiotics	p. 13
Antibacterial Agents	p. 15
Antibiotics that Target the Cell Envelope	p. 17
ß-Lactam Antibiotics	p. 18
Glycopeptides	p. 45
Daptomycin	p. 49
Colistin	p. 51
Antibiotics that Block Protein Production	p. 53
Rifamycins	p. 54
Aminoglycosides	p. 57
Macrolides and Ketolides	p. 61
Tetracyclines and Glycylcyclines	p. 66
Chloramphenicol	p. 70
Clindamycin	p. 72
Streptogramins	p. 74
Linezolid	p. 77
Nitrofurantoin	p. 79
Antibiotics that Target DNA and Replication	p. 81
Sulfa Drugs	p. 82
Quinolones	p. 87
Metronidazole	p. 91
Antimycobacterial Agents	p. 93
Summary of Antibacterial Agents	p. 96
Definitive Therapy	p. 101
Gram-Positive Bacteria	p. 103
Staphylococci	p. 104
Pneumococci	p. 108
Other Streptococci	p. 111
Enterococci	p. 113
Other Gram-Positive Bacteria	p. 117
Gram-Negative Bacteria	p. 121
Enterobacteriaceae	p. 122
Pseudomonas	p. 128
Neisseria	p. 132
Curved Gram-Negative Bacteria	p. 134
Other Gram-Negative Bacteria	p. 139
Anaerobic Bacteria	p. 145
Clostridia	p. 146
Anaerobic Gram-Negative Bacilli	p. 149
Atypical Bacteria	p. 151
Chlamydia	p. 152
Mycoplasma	p. 154
Legionella	p. 156
Brucella	p. 158
Francisella tularensis	p. 160
Rickettsia	p. 162
Spirochetes	p. 164
Treponema pallidum	p. 165
Borrelia burgdorferi	p. 167
Leptospira interrogans	p. 169
Mycobacteria	p. 171
Mycobacterium tuberculosis	p. 172
Mycobacterium avium Complex	p. 175
Mycobacterium leprae	p. 177
Empiric Therapy	p. 179
Pneumonia	p. 181
Urinary Tract Infections	p. 189
Pelvic Inflammatory Disease	p. 194
Meningitis	p. 197
Cellulitis	p. 202
Otitis Media	p. 205
Infective Endocarditis	p. 208
Intravascular-Related Catheter Infections	p. 215
Intra-abdominal Infections	p. 218
Clinical Cases	p. 221
Review Questions and Answers	p. 241
Appendices	p. 253
Dosing of Antibacterial Agents in Adults	p. 253
Dosing of Antibacterial Agents in Children	p. 258
Dosing of Antibacterial Agents in Adults with Renal Insufficiency	p. 264
Antibacterial Agents in Pregnancy	p. 271
Generic and Trade Names of Commonly Used Antibacterial Agents	p. 275
Treatment of Infections Caused by Bacterial Agents of Bioterrorism	p. 279
Medical References	p. 281
Literary References	p. 282
Answers to Chapter Questions	p. 283
Index	p. 287
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