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Basic and Clinical Endocrinology

by
Edition:
6th
ISBN13:

9780838505977

ISBN10:
083850597X
Format:
Paperback
Pub. Date:
11/16/2000
Publisher(s):
Appleton

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Summary

Definitive, concise and current, this top-tier resource focuses on the pathophysiology, diagnosis, and treatment of endocrine disorders. The extensively revised sixth edition reflects the rapid progress made in understanding molecular mechanisms, in addition to improved techniques of diagnosis and therapy.

Table of Contents

Authors iv
Preface xv
Introduction to Endocrinology
1(37)
John D. Baxter
Ralff C. J. Ribeiro
The Endocrine System
1(2)
Paracrine & Autocrine Actions
3(1)
Chemical Composition of Hormones
3(1)
Vitamins & Hormones
4(1)
Hormones & Oncogenes
4(1)
Hormones & the Immune System
5(1)
Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
5(1)
Mechanisms of Hormone Action
6(2)
Hormone Receptors
6(1)
Regulation of Responsiveness to Hormones
7(1)
Interactions Between Hormone Response Systems
8(1)
Classes of Hormone Action
8(3)
Use of Receptors for Classifying Types of Hormone Action
9(1)
Classification of Hormones by the Types of Ligands: Agonists, Antagonists, Partial Agonists-Partial Antagonists, & Inactive Compounds
10(1)
Endocrine & Nervous System Relationships: Neuroendocrinology
11(2)
Neurotransmitters & Hormones
11(1)
Hypothalamic-Pituitary Relationships
11(2)
Gene Expression in Endocrinology & Metabolism: Molecular Basis for Function of the System & Genetic Endocrine Disease
13(1)
Evolution of the Endocrine System
14(3)
Cellular Control Networks & the Origins of Regulatory Chemicals
15(1)
The Origins of Regulatory Proteins
15(1)
The Origins of Hormones
15(1)
Intracellular Communication
16(1)
Evolution of Genes Involved in the Endocrine System
16(1)
Integrative Networks
16(1)
Evolution of the Endocrine Glands
16(1)
Hormone Synthesis & Release
17(1)
Hormone Transport
17(2)
Steroid & Thyroid Hormones & Vitamin D
18(1)
Polypeptide Hormones
18(1)
Metabolism & Elimination of Hormones
19(1)
Peptide Hormones
19(1)
Steroid & Thyroid Hormones & Vitamin D
19(1)
Catecholamine & Eicosanoid Metabolism
19(1)
Regulation of the Endocrine System
20(1)
Actions of Hormones
20(3)
Developmental/Effects
20(1)
Cell Growth & Cancer
20(1)
Central Nervous System Effects
21(1)
Effects on Metabolism
21(1)
Effects on Cardiovascular & Renal Function
21(1)
Effects on Mineral & Water Metabolism
22(1)
Effects on Skeletal Functions
22(1)
Effects on Reproductive Function
22(1)
Release of Other Hormones
22(1)
Effects on Immunologic Functions
23(1)
Disorders of the Endocrine System
23(4)
Endocrine Hypofunction
23(1)
Endocrine Hyperfunction
24(1)
Defects in Sensitivity to Hormones
25(1)
Syndromes of Hormone Excess Due to Administration of Exogenous Hormone or Medication
26(1)
Disorders of the Endocrine Glands not Associated With Endocrine Disease
27(1)
Approach to the Patient With Endocrine Disease
27(7)
History & Physical Examination
27(1)
Laboratory Studies
28(4)
Screening for Endocrine Diseases
32(1)
Treatment of Endocrine Diseases
33(1)
Uses of Hormones in Therapy of Nonendocrine Disease
34(4)
Hormone Synthesis & Release
38(21)
Vishwanath R. Lingappa
Synthia H. Mellon
Overview of Hormone Biosynthesis
38(1)
Membrane Vesicle-Mediated Hormone Export
39(10)
Hormone Export not Mediated by Membrane Vesicles
49(6)
Metabolism, Transport, Elimination, & Regulation of Hormones
55(4)
Mechanisms of Hormone Action
59(21)
David G. Gardner
Receptors
59(18)
Neurotransmitter & Peptide Hormone Receptors
61(1)
Seven-Transmembrane Receptors
62(1)
G Protein Transducers
62(1)
Effectors
63(3)
G Protein-Linked Receptors & Human Disease
66(1)
Growth Factor Receptors
67(2)
Cytokine Receptors
69(1)
Guanylyl Cyclase-Linked Receptors
70(1)
Nuclear Action of Peptide Hormones
71(1)
Nuclear Receptors
72(1)
Steroid Receptor Family
72(2)
Thyroid Receptor Family
74(3)
Nongenomic Effects of the Steroid Hormones
77(1)
Steroid & Thyroid Hormone Receptor Resistance Syndromes
77(3)
Endocrine Autoimmunity
80(20)
Juan Carlos Jaume
Basic Immune Components & Mechanisms
81(9)
Immune Recognition & Response
81(4)
Tolerance
85(5)
Autoimmunity Is Multifactorial
90(1)
Genetic Factors in Autoimmunity
90(1)
Environmental Factors in Autoimmunity
90(1)
Single Gland Autoimmune Syndromes
91(6)
Autoimmune Aspects of Thyroid Disease
91(2)
Autoimmune Aspects of Type 1 Diabetes
93(2)
Autoimmune Aspects of Other Endocrinopathies
95(2)
Autoimmune Polyglandular Syndromes
97(3)
Autoimmune Polyglandular Syndrome I (APS-I)
97(1)
Autoimmune Polyglandular Syndrome II (APS-II)
98(1)
Management of Autoimmune Polyglandular Syndromes
98(2)
Hypothalamus & Pituitary
100(63)
David C. Aron
James W. Findling
J. Blake Tyrrell
Hypothalamic Hormones
105(5)
Anterior Pituitary Hormones
110(9)
ACTH & Related Peptides
110(2)
Growth Hormone
112(2)
Prolactin
114(2)
Thyrotropin
116(1)
Gonadotropins: Luteinizing Hormone, Follicle-Stimulating Hormone
117(2)
Endocrinologic Evaluation of the Hypothalamic-Pituitary Axis
119(7)
Evaluation of ACTH
120(1)
Evaluation of Growth Hormone
121(1)
Evaluation of Prolactin
122(1)
Evaluation of TSH
122(1)
Evaluation of LH & FSH
122(1)
Problems in Evaluation of the Hypothalamic-Pituitary Axis
122(1)
Effects of Pharmacologic Agents on Hypothalamic-Pituitary Function
123(1)
Endocrine Tests of Hypothalamic-Pituitary Function
123(1)
Neuroradiologic Evaluation
123(3)
Pituitary & Hypothalamic Disorders
126(25)
Empty Sella Syndrome
128(1)
Hypothalamic Dysfunction
129(1)
Hypopituitarism
130(6)
Pituitary Adenomas
136(15)
Posterior Pituitary
151(12)
Antidiuretic Hormone (ADH; Vasopressin)
151(1)
Oxytocin
152(1)
Control of Water Balance
152(2)
Diabetes Insipidus
154(4)
Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH)
158(5)
Growth
163(38)
Dennis Styne
Normal Growth
163(15)
Intrauterine Growth
163(1)
The Placenta
164(1)
Classic Hormones of Growth & Fetal Growth
164(1)
Growth Factors & Oncogenes in Fetal Growth
164(1)
Insulin-like Growth Factors, Receptors, & Binding Proteins
164(1)
Insulin
165(1)
Epidermal Growth Factor
165(1)
Fetal Origins of Adult Disease
166(1)
Postnatal Growth
166(10)
Measurement of Growth
176(2)
Skeletal (Bone) Age
178(1)
Disorders of Growth
178(23)
Short Stature Due to Nonendocrine Causes
178(6)
Short Stature Due to Endocrine Disorders
184(11)
The Diagnosis of Short Stature
195(1)
Tall Stature Due to Nonendocrine Causes
196(1)
Tall Stature Due to Endocrine Disorders
197(4)
The Thyroid Gland
201(72)
Francis S. Greenspan
Anatomy & Histology
202(2)
Physiology
204(1)
Structure of Thyroid Hormones
204(1)
Iodine Metabolism
204(2)
Thyroid Hormone Synthesis & Secretion
206(4)
Abnormalities in Thyroid Hormone Synthesis & Release
210(1)
Thyroid Hormone Transport
210(3)
Metabolism of Thyroid Hormones
213(4)
Control of Thyroid Function
217(5)
The Action of Thyroid Hormones
222(3)
Physiologic Changes in Thyroid Function
225(1)
Thyroid Autoimmunity
226(1)
Tests of Thyroid Function
227(1)
Tests of Thyroid Hormones in Blood
227(1)
Evaluation of the Hypothalamic-Pituitary-Thyroid Axis
228(1)
Iodine Metabolism & Biosynthetic Activity
229(2)
Thyroid Imaging
231(1)
Thyroid Ultrasonography or Magnetic Resonance Imaging
231(1)
Thyroid Biopsy
232(1)
Effects of Thyroid Hormones on Peripheral Tissues
232(1)
Measurement of Thyroid Autoantibodies
232(1)
Summary: Clinical Use of Thyroid Function Tests
233(1)
Disorders of the Thyroid
233(2)
Hypothyroidism
235(7)
Hyperthyroidism & Thyrotoxicosis
242(11)
Thyroid Hormone Resistance Syndromes
253(1)
Nontoxic Goiter
254(2)
Thyroiditis
256(2)
Effects of Ionizing Radiation on the Thyroid Gland
258(2)
Thyroid Nodules & Thyroid Cancer
260(13)
Mineral Metabolism & Metabolic Bone Disease
273(61)
Dolores Shoback
Robert Marcus
Daniel Bikle
Gordon Strewler
Cellular & Extracellular Calcium Metabolism
273(1)
Parathyroid Hormone
274(5)
Calcitonin
279(2)
Vitamin D
281(7)
Integrated Control of Mineral Homeostasis
288(1)
Medullary Thyroid Carcinoma
288(1)
Hypercalcemia
288(12)
Hypocalcemia
300(6)
Bone Anatomy & Remodeling
306(4)
Osteoporosis
310(10)
Osteomalacia & Rickets
320(6)
Paget's Disease of Bone (Osteitis Deformans)
326(3)
Renal Osteodystrophy
329(5)
Glucocorticoids & Adrenal Androgens
334(43)
David C. Aron
James W. Findling
J. Blake Tyrrell
Embryology & Anatomy
334(3)
Biosynthesis of Cortisol & Adrenal Androgens
337(5)
Circulation of Cortisol & Adrenal Androgens
342(1)
Metabolism of Cortisol & Adrenal Androgens
342(1)
Biologic Effects
343(8)
Glucocorticoids
343(4)
Adrenal Androgens
347(1)
Laboratory Evaluation
347(4)
Disorders of Adrenocortical Insufficiency
351(9)
Primary Adrenocortical Insufficiency (Addison's Disease)
351(4)
Secondary Adrenocortical Insufficiency
355(1)
Diagnosis of Adrenocortical Insufficiency
355(3)
Treatment of Adrenocortical Insufficiency
358(2)
Prognosis of Adrenocortical Insufficiency
360(1)
Cushing's Syndrome
360(17)
Hirsutism & Virilism
371(1)
Incidental Adrenal Mass
371(2)
Glucocorticoid Therapy for Nonendocrine Disorders
373(4)
Endocrine Hypertension
377(22)
Burl R. Don
Morris Schambelan
Hypertension of Adrenal Origin
377(12)
Hypertension of Renal Origin
389(6)
Other Hormone Systems & Hypertension
395(4)
Adrenal Medulla
399(23)
Alan Goldfien
Anatomy
399(1)
Hormones of the Adrenal Medulla
400(10)
Catecholamines
400(9)
Other Hormones
409(1)
Disorders of Adrenal Medullary Function
410(1)
Adrenal Medullary Hypofunction
410(1)
Adrenal Medullary Hyperfunction
410(1)
Pheochromocytoma
411(11)
Testes
422(31)
Glenn D. Braunstein
Anatomy & Structure-Function Relationships
422(2)
Testes
422(2)
Accessory Structures
424(1)
Physiology of the Male Reproductive System
424(4)
Gonadal Steroids
424(2)
Control of Testicular Function
426(2)
Evaluation of Male Gonadal Function
428(3)
Clinical Evaluation
428(1)
Laboratory Tests of Testicular Function
428(3)
Pharmacology of Drugs Used to Treat Male Gonadal Disorders
431(3)
Androgens
431(2)
Gonadotropins
433(1)
Gonadotropin-Releasing Hormone
434(1)
Clinical Male Gonadal Disorders
434(19)
Klinefelter's Syndrome
434(2)
Bilateral Anorchia
436(1)
Leydig Cell Aplasia
437(1)
Cryptorchidism
437(2)
Noonan's Syndrome (Male Turner's Syndrome)
439(1)
Myotonic Dystrophy
440(1)
Adult Seminiferous Tubule Failure
440(1)
Adult Leydig Cell Failure (Andropause)
441(1)
Erectile Dysfunction (Impotence)
442(2)
Male Infertility
444(2)
Gynecomastia
446(2)
Testicular Tumors
448(5)
Ovaries
453(56)
Alan Goldfien
Anatomy of the Ovaries
453(1)
Hormones of the Ovary
454(6)
Steroid Hormones
454(6)
Relaxin
460(1)
Other Ovarian Hormones & Regulatory Substances
460(1)
The Menstrual Cycle
461(6)
Hormonal Profiles During the Menstrual Cycle
461(2)
The Ovarian Cycle
463(3)
Hormone Interaction & Regulation During the Menstrual Cycle
466(1)
Cyclic Changes in the Female Reproductive Tract
467(4)
Histology of the Endometrium Throughout the Menstrual Cycle
467(2)
Cervical Mucus
469(1)
Vaginal Epithelium
470(1)
Extragenital Symptoms Associated With Normal Menstrual Function
471(2)
Premenstrual Dysmorphic Disorder (Premenstrual Syndrome)
471(1)
Dysmenorrhea
472(1)
Disorders of Ovarian & Menstrual Function
473(15)
Amenorrhea in the Absence of Sexual Maturation
474(1)
Amenorrhea in Patients With Normal Secondary Sex Characteristics
474(6)
Disorders of Androgen Metabolism
480(3)
Hirsutism
483(5)
Anovulatory Bleeding
488(1)
Ovulation Induction
488(2)
Clomiphen Citrate
488(1)
Human Menopausal Gonadotropins (Menotropins)
489(1)
Gonadotropin-Releasing Hormone
490(1)
Bromocriptine
490(1)
Therapeutic Use of Ovarian Hormones & Their Synthetic Analogs
490(1)
Treatment of Primary Hypogonadism
490(1)
Ovarian Suppression
490(1)
Threatened Abortion
490(1)
Inadequate Luteal Phase
491(1)
Diagnostic Uses
491(1)
Inhibitors of Ovarian Function
491(2)
Gonadotropin-Releasing Hormone Analogs & Antagonists
491(1)
Selective Estrogen Receptor Modulators & Antiestrogens
491(1)
Danazol
492(1)
Antiprogestins
492(1)
Antiandrogens
492(1)
Menopause
493(5)
Hormonal Changes
493(1)
Clinical Manifestations of Menopause
494(1)
Management of Menopause
495(3)
Hormonal Contraception (Oral Contraceptives)
498(5)
Pharmacologic Effects of Estrogens & Synthetic Progestins
498(1)
Clinical Uses of Oral Contraceptives
499(1)
Adverse Effects of Oral Contraceptives
500(2)
Noncontraceptive Advantages of Hormonal Contraception
502(1)
Contraindications & Cautions
502(1)
Drug Interactions With Oral Contraceptives
502(1)
Contraception With Progestins
503(1)
Postcoital Contraceptives & Emergency Contraception
503(1)
Infertility
503(6)
Semen Abnormalities
503(1)
Ovulatory Disorders
504(1)
Infertility in the Presence of Ovulation
504(1)
In Vitro Fertilization
505(1)
Gamete Intrafollicular Transfer (GIFT)
505(4)
Abnormalities of Sexual Determination & Differentiation
509(38)
Felix A. Conte
Melvin M. Grumbach
Normal Sex Differentiation
509(6)
Testicular & Ovarian Differentiation
515(2)
Psychosexual Differentiation
517(2)
Abnormal Sex Differentiation
519(1)
Seminiferous Tubule Dysgenesis: Chromatin-Positive Klinefelter's Syndrome & Its Variants
520(2)
Syndrome of Gonadal Dysgenesis: Turner's Syndrome & Its Variants
522(2)
46, XX & 46, XY Gonadal Dysgenesis
524(2)
True Hermaphroditism
526(1)
Female Pseudohermaphroditism
527(4)
P450 Aromatase Deficiency
531(1)
Maternal Androgens & Progestogens
531(1)
Male Pseudohermaphroditism
531(12)
Unclassified Forms of Abnormal Sexual Development in Males
543
Unclassified Forms of Abnormal Sexual Development in Females
542(1)
Management of Patients With Intersex Problems
542(5)
Puberty
547(28)
Dennis Styne
Physiology of Puberty
547(9)
Delayed Puberty or Absent Puberty (Sexual Infantilism)
556(10)
Precocious Puberty (Sexual Precocity)
566(9)
The Endocrinology of Pregnancy
575(28)
Robert N. Taylor
Dan I. Lebovic
Mary C. Martin-Cadieux
Conception & Implantation
575(1)
Fetal-Placental-Decidual Unit
576(1)
Polypeptide Hormones
577(3)
Steroid Hormones
580(1)
Maternal Adaptation to Pregnancy
581(3)
Fetal Endocrinology
584(2)
Endocrine Control of Parturition
586(1)
Endocrinology of the Puerperium
587(2)
Endocrine Disorders & Pregnancy
589(14)
Pregnancy & Pituitary Pathology
589(1)
Pregnancy & Breast Cancer
590(1)
Hypertensive Disorders of Pregnancy
591(1)
Hyperthyroidism in Pregnancy
592(1)
Hypothyroidism in Pregnancy
593(1)
Diabets Mellitus & Pregnancy
593(10)
John L. Kitzmiller
Regulatory Peptides of the Gut
603(20)
Sean J. Mulvihill
Haile T. Debas
Gastrin
607(1)
Cholecystokinin
608(1)
Secretin
609(1)
Somatostatin
609(1)
Bombesin & Gastrin-Releasing Peptide
610(1)
Calcitonin Gene-Related Peptide
611(1)
Gastric Inhibitory Peptide
611(1)
Vasoactive Intestinal Peptide
611(1)
Galanin
612(1)
Substance P
612(1)
Enkephalins
612(1)
Neurotensin
613(1)
Motilin
613(1)
Pancreatic Polypeptide Family
614(1)
Enteroglucagon
614(1)
Abnormalities of Regulatory Peptides in Diseases of the Gastrointestinal Tract
614(5)
Duodenal Ulcer
614(1)
Motility Disorders of the Gastrointestinal Tract
615(1)
Inflammatory Bowel Disease
615(1)
Neuroendocrine Tumors of the Gut
616(1)
Multiple Endocrine Neoplasia Syndromes
616(1)
Zollinger-Ellison Syndrome
616(1)
VIPoma
617(1)
Glucagonoma
617(1)
Carcinoid Tumors & Carcinoid Syndrome
617(1)
Miscellaneous Tumors
618(1)
Minimally Invasive Approaches to Gut Endocrine Tumors
619(1)
Clinical Uses of Gut Peptides
619(4)
Pancreatic Hormones & Diabetes Mellitus
623(76)
Umesh Masharani
John H. Karam
The Endocrine Pancreas
623(10)
Anatomy & Histology
623(1)
Hormones of the Endocrine Pancreas
624(9)
Diabetes Mellitus
633(8)
Classification
633(1)
Type 1 Diabetes Mellitus
633(3)
Type 2 Diabetes
636(2)
Other Specific Types of Diabetes
638(3)
Clinical Features of Diabetes Mellitus
641(2)
Type 1 Diabetes
641(1)
Type 2 Diabetes
642(1)
Laboratory Findings in Diabetes Mellitus
643(4)
Urinalysis
643(1)
Blood Glucose Testing
644(1)
Serum Ketone Determinations
645(1)
Glycosylated Hemoglobin Assays
645(1)
Capillary Morphometry
646(1)
Lipoproteins in Diabetes
646(1)
Diagnosis of Diabetes Mellitus
647(1)
Oral Glucose Tolerance Test
647(1)
Insulin Levels
648(1)
Intravenous Glucose Tolerance Test
648(1)
Treatment of Diabetes Mellitus
648(27)
Diet
651(2)
Oral Agents for the Treatment of Hyperglycemia
653(8)
Insulin
661(5)
Steps in the Management of the Diabetic Patient
666(9)
Acute Complications of Diabetes Mellitus
675(11)
Hypoglycemia
675(3)
Coma
678(8)
Chronic Complications of Diabetes Mellitus
686(8)
Specific Chronic Complications of Diabetes Mellitus
688(6)
Surgery in the Diabetic Patient
694(1)
Diabetics Regulated by Diet Alone
694(1)
Diabetics Taking Oral Hypoglycemic Agents
694(1)
Diabetics Taking Insulin
694(1)
Prognosis for Patients With Diabetes Mellitus
695(4)
Hypoglycemic Disorders
699(17)
John H. Karam
Pathophysiology of the Counterregulatory Response to Neuroglycopenia
699(4)
Classification of Hypoglycemic Disorders
703(1)
Clinical Presentation of Hypoglycemia
704(2)
Specific Hypoglycemic Disorders
706(10)
Symptomatic Fasting Hypoglycemia With Hyperinsulinism
706(6)
Symptomatic Fasting Hypoglycemia Without Hyperinsulinism
712(1)
Nonfasting Hypoglycemia (Reactive Hypoglycemia)
713(3)
Disorders of Lipoprotein Metabolism
716(29)
Mary J. Malloy
John P. Kane
Atherosclerosis
716(1)
Overview of Lipid Transport
717(5)
Differentiation of Disorders of Lipoprotein Metabolism
722(2)
Clinical Descriptions of Primary & Secondary Disorders of Lipoprotein Metabolism
724(8)
The Hypertriglyceridemias
724(1)
Primary Hypertriglyceridemia
725(2)
Secondary Hypertriglyceridemia
727(4)
The Primary Hypercholesterolemias
731(1)
Familial Hypercholesterolemia
731(1)
Familial Combined Hyperlipidemia
732(1)
LP(a) Hyperlipoproteinemia
732(1)
Familial Ligand-Defective Apo B
732(1)
Secondary Hypercholesterolemia
732(1)
Hypothyroidism
732(1)
Nephrosis
733(1)
Immunoglobulin Disorders
733(1)
Anorexia Nervosa
733(1)
Cholestasis
733(1)
The Primary Hypolipidemias
733(4)
Primary Hypolipidemia Due to Deficiency of High-Density Lipoproteins
734(1)
Primary Hypolipidemia Due to Deficiency of Apo B-Containing Lipoproteins
735(1)
Secondary Hypolipidemia
736(1)
Other Disorders of Lipoprotein Metabolism
736(1)
The Lipodystrophies
736(1)
Rare Disorders
737(1)
Treatment of Hyperlipidemia
737(8)
Dietary Factors in the Management of Lipoprotein Disorders
738(1)
Drugs Used in Treatment of Hyperlipoproteinemia
739(1)
Bile Acid Sequestrants
739(1)
Niacin (Nicotinic Acid)
740(1)
Fibric Acid Derivatives
741(1)
HMG-CoA Reductase Inhibitors
741(1)
Combined Drug Therapy
742(1)
Possible Untoward Consequences of Lipid-Lowering Therapy
743(2)
Obesity & Overweight
745(17)
Marc K. Hellerstein
Elizabeth J. Parks
Controversies & Uncertainties Regarding the Pathogenesis of Obesity
754(1)
Survey of Treatment Approaches & Their Efficacy
755(4)
Dietary Therapies
755(1)
Surgical Treatment of Obesity
756(1)
Pharmacologic Therapies
756(3)
Other Conditions Affected by Treatment of Obesity or Overweight
759(1)
Type 2 Diabetes Mellitus
759(1)
Hyperlipidemia
759(1)
Polycystic Ovarian Syndrome
759(1)
Hypertension
759(1)
Gallstones
759(1)
Osteoarthritis & Other Weight-Sensitive States
759(1)
A Systematic Approach to the Treatment of Obesity
759(3)
Hormones & Cancer
762(16)
Debasish Tripathy
Christopher C. Benz
Hormonal Effects on Tumors
762(3)
Growth Promotion & Malignant Transformation
762(2)
Tumor Growth Mediated by Autocrine & Paracrine Factors
764(1)
Steroid-Dependent Tumors
765(1)
Tumors Affecting Endocrine Status
765(2)
Nonsecretory Tumors
765(1)
Secretory Tumors
765(1)
Treatment-Induced Endocrinopathy
766(1)
Endocrine Therapy for Cancer
767(3)
Steroid Receptors & Treatment
767(1)
Primary Modalities of Endocrine Intervention
768(1)
Combination Endocrine Therapy
769(1)
Chemo-Endocrine Therapy
770(1)
Clinical Problems
770(8)
Breast Cancer in Women
770(4)
Breast Cancer in Men
774(1)
Endometrial Cancer
774(1)
Prostatic Cancer
775(1)
Miscellaneous Tumors
776(2)
Humoral Manifestations of Malignancy
778(14)
Dolores Shoback
Janet Funk
Ectopic Hormone & Receptor Syndromes
778(1)
Hypercalcemia of Malignancy
779(4)
Ectopic Cushing's Syndrome
783(2)
Syndrome of Inappropriate ADH (SIADH) Secretion
785(1)
Non-Islet Cell Tumors & Hypoglycemia
786(1)
Other Hormones Secreted by Tumors
787(1)
Oncogenic Osteomalacia
788(1)
Gut Hormones
789(1)
Erythropoietin
789(1)
Renin
789(3)
Multiple Endocrine Neoplasia
792(10)
David G. Gardner
Multiple Endocrine Neoplasia Type 1 (MEN 1)
792(5)
Multiple Endocrine Neoplasia Type 2 (MEN 2)
797(5)
Geriatric Endocrinology
802(21)
Susan L. Greenspan
Neil M. Resnick
Thyroid Function & Disease
802(3)
Disorders of the Thyroid Gland
803(2)
Carbohydrate Intolerance & Diabetes Mellitus
805(3)
Aging & the Physiology of Carbohydrate Intolerance
805(1)
Diabetes Mellitus
806(2)
Nonketotic Hyperosmolar Coma
808(1)
Osteoporosis & Calcium Homeostasis
808(8)
Osteoporosis
808(7)
Hyperparathyroidism
815(1)
Changes in Water Balance
816(1)
Hypernatremia
816(1)
Hyponatremia
816(1)
Hyporeninemic Hypoaldosteronism
816(1)
Glucocorticoids & Stress
817(1)
Disorders of the Hypothalamic-Pituitary-Adrenal Axis
817(1)
Changes in Reproductive Function in Men
818(1)
Benign Prostatic Hyperplasia
819(4)
Endocrine Emergencies
823(23)
David G. Gardner
Francis S. Greenspan
Myxedema Coma
823(1)
Thyroid Storm
824(1)
Thyrotoxic Periodic Paralysis
825(1)
Amiodarone Induced Thyrotoxicosis
826(1)
Acute Adrenal Insufficiency
827(1)
Pituitary Apoplexy
828(1)
Diabetic Ketoacidosis
829(3)
Nonketotic Hyperosmolar Coma
832(3)
Hypercalcemic Crisis
835(2)
Acute Hypocalcemia
837(2)
Hyponatremia
839(2)
Diabetes Insipidus
841(5)
AIDS Endocrinopathies
846(7)
Deborah E. Sellmeyer
Carl Grunfeld
Thyroid Disorders
846(1)
Adrenal Disorders
847(2)
Bone & Mineral Disorders
849(1)
Gonadal Disorders
849(1)
Pituitary Disorders
850(1)
Pancreatic Disorders
850(1)
Lipid Disorders
851(1)
Conclusion
851(2)
Appendix: Table of Normal Hormone Reference Ranges 853(14)
Index 867


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