Basic Immunology : Functions and Disorders of the Immune System with Student Consult Online Access

by Abbas, Abul K.

• ISBN13: 9781416046882
• ISBN10: 1416046887
• Edition: 3rd
• Format: Paperback
• Copyright: 2008-02-20
• Publisher: Elsevier Science Health Science div

Summary

Heres a readable and concise introduction to the workings of the human immune system, with emphasis on clinical relevance. The format makes learning easy with short, easy-to-read chapters, color tables, key point summaries, and review questions in every chapter. Relates basic science to clinical disorders through clinical cases for better application in a real-world setting. Includes a full Glossary to keep you on the cutting edge of immunologic terminology. Includes appendices summarizing the features of CD Molecules, a handy Glossary, and Clinical Cases that test your understanding of how the immune system functions in health and disease. Illustrated with beautiful full-color artwork for enhanced visual learning. Provides the most up-to-date immunology information including coverage of regulatory T cells, and biology of the Th17 subset of CD4+ T cells to keep you completely current. Access integration links through included STUDENT CONSULT access for more in-depth study.

Author Biography

Abul K. Abbas, MBBS, Professor and Chair Department of Pathology, University of California San Francisco, School of Medicine, San Francisco, California Andrew H. Lichtman, MD, PhD, Associate Professor of Pathology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts

Table of Contents

Introduction to the Immune System: The Nomenclature, General Properties, and Components of the Immune System	p. 1
Innate Immunity: The Early Defense Against Infections	p. 23
Antigen Capture and Presentation to Lymphocytes: What Lymphocytes See	p. 45
Antigen Recognition in the Adaptive Immune System: Structure of Lymphocyte Antigen Receptors and the Development of Immune Repertoires	p. 67
Cell-Mediated Immune Responses: Activation of T Lymphocytes by Cell-Associated Microbes	p. 89
Effector Mechanisms of Cell-Mediated Immunity: Eradication of Intracellular Microbes	p. 113
Humoral Immune Responses: Activation of B Lymphocytes and Production of Antibodies	p. 131
Effector Mechanisms of Humoral Immunity: The Elimination of Extracellular Microbes and Toxins	p. 153
Immunological Tolerance and Autoimmunity: Self-Nonself Discrimination in the Immune System and Its Failure	p. 173
Immune Responses Against Tumors and Transplants: Immunity to Noninfectious Transformed and Foreign Cells	p. 189
Hypersensitivity: Disorders Caused by Immune Responses	p. 205
Congenital and Acquired Immunodeficiencies: Diseases Caused by Defective Immune Responses	p. 223
Suggested Readings	p. 239
Glossary	p. 245
Principal Features of CD Molecules	p. 273
Clinical Cases	p. 283
Index	p. 293
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