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This book provides a clear presentation of the basic concepts of pharmacokinetics through graphs and simulations. Expanding on the first edition, the text covers the biological and physiological basis of the different pharmacokinetic behavior. It also contains seven new chapters with topics including bioequivalence, pharmacogenomics, pharmacokinetic basis of drug interaction, computers in pharmacokinetics, and physiological pharmacokinetic modeling and animal scale-up. In addition, the award-winning updated companion CD includes a section for pharmacokinetic simulations and pharmacodynamic simulations, aiding users interested in simulating the pharmacokinetic behavior of drugs.