The Biochemical Basis of Neuropharmacology

by Cooper, Jack R.; Bloom, Floyd E.; Roth, Robert H.

• ISBN13: 9780195140088
• ISBN10: 0195140087
• Edition: 8th
• Format: Paperback
• Copyright: 2002-10-17
• Publisher: Oxford University Press

Summary

This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology,residents in psychiatry and neurology, and clinicians and scientists. Both authoriative and very readable, it has been thoroughly updated for each edition. In the 8th Edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, molecular genetics,the major problem of drug delivery to the brain, and the growing recognition of nicotin receptors in the brain and their possible involvement in Alxheimer's and Parkinson's diseases. In addition, the book's format has been enlarged and a second color added to many of the illustrations.

Author Biography

Jack R. Cooper, Ph.D., is Emeritus Professor of Pharmacology, Yale University School of Medicine Floyd E. Bloom, M.D., is Chairman, Department of Neuropharmacology, The Scripps Research Institute Robert H. Roth, Ph.D., is Professor of Pharmacology and Psychiatry, Yale University School of Medicine

Table of Contents

Introduction	p. 1
Cellular Foundations of Neuropharmacology	p. 7
Molecular Foundations of Neuropharmacology	p. 39
Receptors	p. 65
Modulation of Synaptic Transmission	p. 85
Amino Acid Transmitters	p. 105
Acetylcholine	p. 151
Norepinephrine and Epinephrine	p. 181
Dopamine	p. 225
Serotonin (5-Hydroxytryptamine), Histamine, and Adenosine	p. 271
Neuroactive Peptides	p. 321
Cellular Mechanisms in Learning and Memory	p. 357
Treating Neurological and Psychiatric Diseases	p. 373
Index	p. 401
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