Biochemistry and Molecular Biology

by Elliott, William H.; Elliott, Daphne C.

• ISBN13: 9780199226719
• ISBN10: 0199226717
• Edition: 4th
• Format: Paperback
• Copyright: 2009-03-25
• Publisher: Oxford University Press

Summary

Molecular tools and biochemical processes are now central to much of our understanding of the biological and biomedical sciences - from the study of ecological interactions and animal behaviour to the causes and treatment of disease. Biochemistry and Molecular Biology is the perfect resourcefor any student who needs to know the principles of this fascinating subject - whether they are studying biology or biochemistry, biomedical science or nutrition. The book blends the fundamentals of cell biology and biochemistry with the latest advances in genomics and proteomics to give acontemporary, accurate depiction of the field, while always maintaining a wonderful clarity, enriched by carefully layered explanations and vivid illustrations. It is the ideal companion as you explore biochemistry and molecular biology for the first time. Online Resource Centre: The Online Resource Centre features: For registered adopters of the book: DT Figures from the book available to download; DT A new test bank of questions, with feedback keyed to the book, for use in formative and summative assessment For students: DT A library of weblinks cited in the text; DT A hyperlinked bibliography of literature articles cited in the text; DT An extensive bank of multiple-choice questions for self-directed learning

Author Biography

Professor William H. Elliott, Emeritus Professor, Department of Biochemistry, University of Adelaide, Australia
Dr Daphne C. Elliott, formerly Lecturer, Department of Biochemistry, Flinders University, Adelaide, Australia

Table of Contents

Basic concepts of life

The basic molecular themes of life

Cells and viruses

Energy considerations in biochemistry

Structure and function of proteins and membranes

The structure of proteins

Methods in protein investigation

Enzymes

The cell membrane and membrane proteins

Muscle contraction, the cytoskeleton, and molecular motors

Metabolism

Food digestion, absorption, distribution to the tissues and appetite control

Mechanisms of transport, storage and mobilisation of dietary components

Principles of energy release from food

Glycolysis, the citric acid cycle, and the electron transport system

Energy release from fat

The synthesis of fat and related compounds

Synthesis of glucose (gluconeogenesis)

Strategies for metabolic control and their applications to carbohydrate and fat metabolism

Why should there be an alternative pathway of glucose oxidation?

The pentose phosphate pathway

Raising electrons of water back up the energy scale - photosynthesis

Amino acid metabolism

Nucleotide synthesis and metabolism

Information storage and utilisation

Genome

DNA synthesis, repair and recombination

Gene transcription and control

Protein synthesis and controlled protein breakdown

The RNA world - RNA microgenes and RNA interference

Protein sorting and delivery

Cell signalling

Manipulating DNA and genes

Molecular biology in health and disease

Special topics: blood clotting, xenobiotic metabolism, oxygen free radicals

The immune system

The cell cycle and its control

Apoptosis

Cancer

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