Bioinformatics : Sequence and Genome Analysis

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  • Edition: 2nd
  • Format: Paperback
  • Copyright: 8/16/2004
  • Publisher: Oxford
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Supplemental Materials

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  • The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.


As more species#x19; genomes are sequenced, computational analysis of these data has become increasingly important. The second, entirely updated edition of this widely praised textbook provides a comprehensive and critical examination of the computational methods needed for analyzing DNA, RNA, and protein data, as well as genomes. The book has been rewritten to make it more accessible to a wider audience, including advanced undergraduate and graduate students. New features include chapter guides and explanatory information panels and glossary terms. New chapters in this second edition cover statistical analysis of sequence alignments, computer programming for bioinformatics, and data management and mining. Practically oriented problems at the ends of chapters enhance the value of the book as a teaching resource. The book also serves as an essential reference for professionals in molecular biology, pharmaceutical, and genome laboratories.

Table of Contents

Historical introduction and overviewp. 1
Collecting and storing sequences in the laboratoryp. 29
Alignment of pairs of sequencesp. 65
Introduction to probability and statistical analysis of sequence alignmentsp. 121
Multiple sequence alignmentp. 163
Sequence database searching for similar sequencesp. 227
Phylogenetic predictionp. 281
Prediction of RNA secondary structurep. 327
Gene prediction and regulationp. 361
Protein classification and structure predictionp. 409
Genome analysisp. 495
Bioinformatics programming using Perl and Perl modulesp. 549
Analysis of microarraysp. 611
Table of Contents provided by Blackwell. All Rights Reserved.

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