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Evolving bio and nanotechnologies encompass a vast and diverse assortment of products and materials that have the potential to bring about major changes in our lives. However, remarkable benefits can all too often be accompanied by potential detrimental consequences.Biotechnology andNanotechnology Risk Assessment: Minding and Managing the Potential Threats around Uspresents contemporary research efforts, public policy and regulatory aspects, and ethical issues focused on recognizing, understanding, and responding to these consequences in terms of human and environmental impacts. This includes topics relevant to manufactured nanoparticle toxicity in relation to human, animal, and microorganism exposure, consequent environmental fate and impacts, and downstream effects on other emerging nano/bio industries. Emerging tools and modeling approaches for enhanced understanding of bio and nanotechnology risks are presented in order to provide a comprehensive and balanced overview of nano/biotechnology risk assessment.