| Introduction -- Guide to the Talks |
|
1 | (18) |
|
|
|
|
|
|
Polymorphic Genotype Matching in Acquired Creutzfeldt-Jakob Disease: An Analysis of Donor/Recipient Case Pairs |
|
|
19 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Human Prion Protein Gene Mutation at Codon 183 Associated with an Atypical Form of Prion Disease |
|
|
25 | (8) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Fatal Familial Insomnia: A Human Model of Prion Disease |
|
|
33 | (4) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Mechanisms of Phenotypic Heterogeneity in Human Prion Diseases |
|
|
37 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Transgenic Mice with Neuron-Specific Expression of a Hamster Prion Protein Minigene Are Susceptible to Hamster Scrapie Agent |
|
|
43 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
The Use of Transgenic Mice in the Investigation of Transmissible Spongiform Encephalopathies |
|
|
49 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Large-Scale Sequencing of Human, Mouse, and Sheep Prion Protein Genes |
|
|
59 | (18) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Electron Microscopy in Prion Research: Tubulovesicular Structures Are Not Composed of Prion Protein (PrP) but They May Be Intimately Associated with PrP Amyloid Fibrils |
|
|
77 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Familial Prion Diseases Modeled in Cell Culture |
|
|
87 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Yeast Approach to Protein "Prionization": SUP35-[PSI] System |
|
|
99 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Prions of Yeast: Genetic Evidence that the Non-Mendelian Elements, [PSI] and [URE3] Are Altered Self-Replicating Forms of Sup35p and Ure2p, Respectively |
|
|
111 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Early Clinical Detection of Brain Diseases in Animals |
|
|
123 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Prion Biology and Diseases -- Fatal Conformations of Proteins during a Journey from Heresy to Orthodoxy |
|
|
135 | (6) |
|
|
|
|
|
|
New Variant Creutzfeldt-Jakob Disease |
|
|
141 | (6) |
|
|
|
|
|
|
The Molecular Basis of Cellular Dysfunction in Prion Diseases |
|
|
147 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Presenilin Proteins and the Pathogenesis of Early-Onset Familial Alzheimer's Disease: Beta-Amyloid Production and Parallels to Prion Diseases |
|
|
159 | (18) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Polyene Antibiotics in Experimental Transmissible Subacute Spongiform Encephalopathies |
|
|
177 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Scrapie Pathogenesis in Brain Grafts |
|
|
187 | (10) |
|
|
|
|
|
|
|
|
|
|
|
Structural Properties of Recombinant Human Prion Protein |
|
|
197 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Autonomous Folding and Three-Dimensional Structure of the Carboxy-Terminal Domain of the Mouse Prion Protein, PrP (121-231) |
|
|
203 | (14) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Protease-Resistant Prion Protein Formation |
|
|
217 | (8) |
|
|
|
|
|
|
|
|
|
|
|
Biophysical Studies on Structure Structural Transitions and Infectivity of the Prion Protein |
|
|
225 | (20) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Amyloidogenesis in Transmissible Spongiform Encephalopathies |
|
|
245 | (8) |
|
|
|
|
|
|
|
|
|
|
|
Neuronal Degeneration and Cell Death in Prion Disease |
|
|
253 | (16) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Clinical, Pathological, and Molecular Characterization of Gerstmann-Straussler-Scheinker Disease in the Indiana Kindred (PRNP F198S) |
|
|
269 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Studies on the Pathogenesis of Scrapie and the Purification of Scrapie Agent in the Hamster Model |
|
|
279 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PrP Peptides as a Tool to Investigate the Pathogenesis of Prion Protein Amyloidoses |
|
|
285 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Properties of the Prion Proteins in Creutzfeldt Jakob Disease Patients Heterozygous for the E200K Mutation |
|
|
291 | (6) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Strain Variation in Scrapie and BSE |
|
|
297 | (2) |
|
|
|
|
|
|
Transmission Studies of Fatal Familial Insomnia |
|
|
299 | (4) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Molecular, Genetic, and Transgenetic Studies of Human Prion Disease |
|
|
303 | (2) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Molecular Biology of Prion Propagation |
|
|
305 | (2) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Ultrastructural and Immunocytochemical Studies on Prion Pathogenesis |
|
|
307 | (2) |
|
|
|
|
|
|
Overview of the BSE Epidemic |
|
|
309 | (2) |
|
|
|
|
|
|
Assessing Risks of BSE Transmission to Humans |
|
|
311 | (2) |
|
|
|
|
|
|
Human Activities Are Causing Selection of Pathogenic Agents |
|
|
313 | (2) |
|
|
|
|
|
|
Pathogenic Similarity of Slow Infections, Induced by Prions and Virions |
|
|
315 | (2) |
|
|
|
|
|
|
Protein Floding and Misfolding |
|
|
317 | (2) |
|
|
|
|
|
|
CJD Risk Factors: Analysis of 104 Patients |
|
|
319 | (2) |
|
|
|
|
|
|
Concluding Talk: Prions from a Physicist's Viewpoint -- Is the `Protein Only' Hypothesis Correct? |
|
|
321 | (20) |
|
|
|
|
|
| List of Speakers |
|
341 | (2) |
| Names and Addresses of Participants |
|
343 | (10) |
| Index |
|
353 | |
Shopping Cart
