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9780879934996

Birth Asphyxia and the Brain Basic Science and Clinical Implications

by ; ;
  • ISBN13:

    9780879934996

  • ISBN10:

    0879934999

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2002-06-24
  • Publisher: Wiley-Blackwell

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Summary

This text presents a state-of-the-art review of asphyxial brain injury to the foetus and new born, a leading source of both neonatal mortality and long-term neurologic disability. Beginning with an historical overview of birth-related injury, followed by an epidemiologic review of the relationship of birth injury to later neuromotor disability, it provides a detailed analysis and exhaustive review of each aspect. The contributors are among the most knowledgeable international authorities in the field; they have synthesized a uniformity of medical and scientific quality, clarity of style, and thoroughness of scope. Continual emphasis is placed on the material's relevance and usefulness to clinicians; equally important is the emphasis on communication between clinicians and basic neuroscientists.The task of paediatricians and neonatologists in coming years will be to better understand the mechanism of brain damage, the prediction of disability, and the introduction of efficacious neuroprotective strategies. To that end, this volume deserves wide recognition by physicians in all disciplines related to neonatal care, including paediatricians, neonatologists, neurologists, obstetricians, family practitioners, nurses and legal counsel.

Author Biography

Steven M. Donn is the editor of Birth Asphyxia and the Brain: Basic Science and Clinical Implications, published by Wiley.

Sunil Sinha is the editor of Birth Asphyxia and the Brain: Basic Science and Clinical Implications, published by Wiley.

Table of Contents

Foreword
History and Epidemiology
Cerebral Palsy and Its Causes: Historical Perspectives
The Relationship of Birth Asphyxia to Later Motor Disability
Basic Science
The Biochemical Neurotoxic Cascade in Hypoxic-Ischemic Injury
Inflammation and Neonatal Brain Injury
Glucose, Acidosis, and the Developing Brain
Energy Consequences of Cerebral Hypoxia-Ischemia
Apoptosis and Necrosis in Perinatal Brain Injury
Effects of Nitric Oxide on Neuronal and Cerebrovascular Function
Free Radical-Mediated Processes
Clinical Implications
Antepartum Hypoxemia and the Developing Fetus
Intrapartum Hypoxic-Ischemic Brain Injury
Clinical Management of the Asphyxiated Newborn
Neuroimaging of Hypoxic-Ischemic Encephalopathy
Thermal Influence on the Asphyxiated Newborn
Medico-Legal Aspects
Medico-Legal Implications of Hypoxic-Ischemic Brain Injury
Table of Contents provided by Publisher. All Rights Reserved.

Supplemental Materials

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

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