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Interpreting the Medical Literature: Practical Epidemiology for Clinicians,9780071054515
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Interpreting the Medical Literature: Practical Epidemiology for Clinicians


Author(s): Gehlbach, Stephen H.
ISBN10:  0071054510
ISBN13:  9780071054515
Format:  Paperback
Pub. Date:  3/1/1993
Publisher(s): McGraw-Hill

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SummaryTable of Contents
This text helps students and clinicians better understand the medical literature by instilling the essential skills to critically evaluate article findings. The fundamental principles of study design, data analysis, statistical significance and data interpretation are examined in depth. Easy to read and highly practical, the test is an invaluable aid to researchers, practitioners and students.
Preface ix
Tasting an Article
1(13)
Validity
3(1)
Reasons to Read
4(2)
The Bones of an Article
6(3)
Approaching an Article
9(5)
Study Design: General Considerations
14(20)
Descriptive Studies
15(3)
Explanatory Studies
18(9)
More Confusing Terminology
27(5)
Summary
32(2)
Study Design: The Case-Control Approach
34(21)
Advantages of the Case-Control Design
35(1)
Problems of Case-Control Designs
36(15)
Summary
51(4)
Study Design: The Cross-Sectional and Follow-up Approaches
55(23)
Cross-Sectional Designs
57(10)
Follow-up Studies
67(7)
Summary
74(4)
Study Design: The Experimental Approach
78(33)
Subjects: Who Gets in
79(8)
Controls: Their Presence and Comparability
87(6)
The Intervention or Treatment
93(6)
Allocation: Subject Assignment
99(5)
Attrition
104(2)
End Points
106(1)
Summary
107(4)
Making Measurements
111(16)
Reliability and Validity
112(1)
Variability of the Unsystematic Sort
113(3)
Systematic Error
116(6)
Controlling Measurement Error
122(2)
Summary
124(3)
Interpretation: Distributions, Averages, and the Normal
127(18)
Frequency Distributions
128(2)
Measures of Central Tendency
130(2)
Indicators of Variability
132(2)
Normality
134(6)
Regression to the Mean
140(3)
Summary
143(2)
Interpretation: Statistical Significance
145(16)
Inference
146(1)
Sampling Variability
147(1)
The Null Hypothesis and Statistical Significance
148(1)
Some Problems of Statistical Significance
149(5)
Beta Errors and Statistical Power
154(2)
Confidence Intervals
156(1)
Testing for Statistical Significance May Be Irrelevant
157(2)
Summary
159(2)
Interpretation: Some Statistical Tests
161(17)
Tests for Continuous Data
166(3)
Correlation
169(2)
Regression
171(5)
Summary
176(2)
Interpretation: Sensitivity, Specificity, and Predictive Value
178(23)
Prevalence
184(3)
Making Choices
187(1)
Multiple Tests
188(5)
Spectrum
193(1)
Standards
194(2)
Cost Considerations
196(2)
Summary
198(3)
Interpretation: Risk
201(13)
Statements of Risk
202(1)
Relative Risk
203(1)
Relative Risk and Study Design
204(5)
Attributable Risk
209(1)
Balancing Risks
210(2)
Summary
212(2)
Interpretation: Causes
214(17)
Confounding
215(3)
Dealing with Confounding
218(5)
Making Associations into Causes
223(6)
Summary
229(2)
Case Series, Editorials, and Reviews
231(21)
Case Series
232(7)
Editorials and Letters to the Editor
239(4)
Reviews
243(6)
Summary
249(3)
A Final Word
252(7)
Clarity
253(2)
Apologies, Tentative Conclusions, Self-Criticism, and the Like
255(1)
The Final Word
256(2)
Summary
258(1)
Index 259

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