| Contributors |
|
xv | |
| Preface |
|
xxi | |
| About the Editors |
|
xxv | |
| Foreword Cytokines as Mediators of Central and Peripheral Immune-Neuroendocrine Interactions |
|
1 | (20) |
|
|
|
|
|
|
|
|
|
|
| PART I NERVOUS SYSTEM EFFECTS ON IMMUNITY |
|
|
Exploring the Phylogenetic History of Neural-Immune System Interactions |
|
|
21 | (34) |
|
|
|
|
|
|
|
|
|
|
|
Innervation of Lymphoid Organs---Association of Nerves with Cells of the Immune System and Their Implications in Disease |
|
|
55 | (58) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Introduction to Biological Signaling in Psychoneuroimmunology |
|
|
113 | (48) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Neurotransmitter Receptors on Lymphocytes and Other Lymphoid Cells |
|
|
161 | (36) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Catecholamines, Sympathetic Nerves, and Immunity |
|
|
197 | (20) |
|
|
|
|
|
|
Regulation of Immune and Inflammatory Reactions in Local Microenvironments by Sensory Neuropeptides |
|
|
217 | (14) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Neural Influences on Cell Adhesion Molecules and Lymphocyte Trafficking |
|
|
231 | (10) |
|
|
|
|
|
|
Age-Related Alterations in Neural-Immune Interactions and Neural Strategies in Immunosenescence |
|
|
241 | (48) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PART II NEUROENDOCRINE EFFECTS ON IMMUNITY |
|
|
Neuroendocrine Regulation of Macrophage and Neutrophil Function |
|
|
289 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Bidirectional Effects of Stress and Glucocorticoid Hormones on Immune Function: Possible Explanations for Paradoxical Observations |
|
|
301 | (38) |
|
|
|
|
|
|
|
|
|
|
|
Growth Hormone and Insulin-like Growth Factor as Cytokines in the Immune System |
|
|
339 | (24) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
The Hypothalamo-Pituitary-Gonadal Axis and the Immune System |
|
|
363 | (28) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Preproenkephalin: An Unappreciated Neuroimmune Communicator |
|
|
391 | (14) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Opioidergic Modulation of the Immune System |
|
|
405 | (10) |
|
|
|
|
|
|
|
|
|
|
|
Marijuana, the Cannabinoid System, and Immunomodulation |
|
|
415 | (18) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Melatonin and Immune Function |
|
|
433 | (12) |
|
|
|
|
|
|
Biological Rhythms and Immune Function |
|
|
445 | (38) |
|
|
|
|
|
|
|
|
|
|
| PART III IMMUNE SYSTEM EFFECTS ON THE NERVOUS SYSTEM |
|
|
Cytokines, CVSs, and the Blood-Brain Barrier |
|
|
483 | (16) |
|
|
|
|
|
|
Secretion of Immunomodulatory Mediators from the Brain: An Alternative Pathway of Neuroimmunomodulation |
|
|
499 | (18) |
|
|
|
|
|
|
Central Cytokines: Effects on Peripheral Immunity, Inflammation, and Nociception |
|
|
517 | (30) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Production and Influence of Inflammatory Cytokines in Diseases of the Adult Central Nervous System |
|
|
547 | (16) |
|
|
|
|
|
|
Multiple Routes of Action of Interleukin-1 on the Nervous System |
|
|
563 | (22) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Effects of Interleukin-2 and Interferons on the Nervous System |
|
|
585 | (48) |
|
|
|
|
|
|
The Hypothalamo-Pituitary-Adrenal Axis Response to Immune Signals |
|
|
633 | (16) |
|
|
|
|
|
|
Effects of Cytokines and Infections on Brain Neurochemistry |
|
|
649 | (18) |
|
|
|
|
|
|
Sleep in Health and Disease |
|
|
667 | (20) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
687 | (16) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cytokine Effects on Behavior |
|
|
703 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PART IV BEHAVIORAL EFFECTS ON IMMUNITY |
|
|
Conditioning and Immunity |
|
|
3 | (32) |
|
|
|
|
|
|
|
|
|
|
|
From Psychoneuroimmunology to Ecological Immunology: Life History Strategies and Immunity Trade-offs |
|
|
35 | (14) |
|
|
|
|
|
|
|
|
|
|
|
Fetal Alcohol Syndrome and Immunity |
|
|
49 | (24) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Effects of Early Rearing Experiences and Social Interactions on Immune Function in Nonhuman Primates |
|
|
73 | (14) |
|
|
|
|
|
|
|
|
|
|
|
Individual Difference Factors in Psychoneuroimmunology |
|
|
87 | (24) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
111 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Immune Responses to Acute Exercise: Hemodynamic, Hormonal, and Cytokine Influences |
|
|
123 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
|
133 | (28) |
|
|
|
|
|
|
Alternative Medicine and the Immune System |
|
|
161 | (12) |
|
|
|
|
|
|
Behavioral Genetics and Immunity |
|
|
173 | (16) |
|
|
|
|
|
| PART V STRESS AND IMMUNITY |
|
|
Effects of Stress on Immune Functions: An Overview |
|
|
189 | (38) |
|
|
|
|
|
|
Mechanisms of Stress-Induced Modulation of Immunity in Animals |
|
|
227 | (24) |
|
|
|
|
|
|
|
|
|
|
|
Nitric Oxide and Neural-Immune Interactions |
|
|
251 | (14) |
|
|
|
|
|
|
Immunologic Effects of Acute versus Chronic Stress in Animals |
|
|
265 | (14) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Acute and Chronic Effects of Space Flight on Immune Functions |
|
|
279 | (12) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Immunologic Sequelae of Surgery and Trauma |
|
|
291 | (26) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Stress-Induced Autonomic and Immunologic Reactivity |
|
|
317 | (18) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Neuroendocrine and Immune Alterations Following Natural Disasters and Traumatic Stress |
|
|
335 | (14) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| PART VI PSYCHONEUROIMMUNOLOGY AND PATHOPHYSIOLOGY |
|
|
Impact of Brain Injury on Immune Function |
|
|
349 | (24) |
|
|
|
|
|
|
Immunological States Associated with Schizophrenia |
|
|
373 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
|
383 | (16) |
|
|
|
|
|
|
Psychosocial Influences, Immune Function, and the Progression of Autoimmune Disease |
|
|
399 | (22) |
|
|
|
|
|
|
|
|
|
|
|
Ovarian and Sympathoadrenal Hormones, Pregnancy, and Autoimmune Diseases |
|
|
421 | (12) |
|
|
|
|
|
|
|
|
|
|
|
Neuroendocrine Influences on Autoimmune Disease: Multiple Sclerosis |
|
|
433 | (16) |
|
|
|
|
|
|
|
|
|
|
|
The Neuroendocrine System and Rheumatoid Arthritis: Focus on the Hypothalamo-Pituitary-Adrenal Axis |
|
|
449 | (22) |
|
|
|
|
|
|
|
|
|
|
|
Neuroendocrine Influences on the Pathogenesis of Psoriasis |
|
|
471 | (12) |
|
|
|
|
|
|
|
|
|
|
|
Psychoneuroimmune Interactions in Infectious Disease: Studies in Animals |
|
|
483 | (16) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Stress, Immunity, and Susceptibility to Upper Respiratory Infection |
|
|
499 | (12) |
|
|
|
|
|
|
|
|
|
|
|
Physical Activity and Upper Respiratory Infection |
|
|
511 | (14) |
|
|
|
|
|
|
|
|
|
|
|
Psychological Risk Factors and Immune System Involvement in Cardiovascular Disease |
|
|
525 | (20) |
|
|
|
|
|
|
|
|
|
|
|
The Impact of Stress, Catecholamines, and the Menstrual Cycle on NK Activity and Tumor Development: From in Vitro Studies to Biological Significance |
|
|
545 | (20) |
|
|
|
|
|
|
|
|
|
|
|
Psychosocial Effects on Immune Function and Disease Progression in Cancer: Human Studies |
|
|
565 | (18) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Psychosocial Influences on the Progression of HIV Infection |
|
|
583 | (30) |
|
|
|
|
|
|
|
|
|
|
|
|
|
613 | (14) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Psychoneuroimmune Interactions in Periodontal Disease |
|
|
627 | (18) |
|
|
|
|
|
|
|
|
|
|
|
Clinical, Experimental, and Translational Psychoneuroimmunology Research Models in Oral Biology and Medicine |
|
|
645 | (26) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Helicobacter pylori, Immune Function, and Gastric Lesions |
|
|
671 | (16) |
|
|
|
|
|
|
|
|
|
|
|
Alcoholism and Immune Function |
|
|
687 | (14) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Psychoneuroimmunology and Aging |
|
|
701 | (18) |
|
|
|
|
|
|
|
|
|
|
| Author Index |
|
719 | (128) |
| Subject Index |
|
847 | |