| Preface |
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Establishment of the OLETF rat |
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1 | (12) |
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Genetic background of the OLETF rat |
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13 | (16) |
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| Pathogenesis |
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Morphological changes in the pancreatic islets of the OLETF rat |
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29 | (8) |
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Functional changes in the pancreatic islets of the OLETF rat |
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37 | (8) |
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Poor capacity for proliferation of pancreatic β-cells in the OLETF rat |
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45 | (10) |
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Hypertriglyceridemia as a factor which causes abnormal insulin secretion in the OLETF rat |
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55 | (12) |
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Molecular mechanism(s) of insulin resistance in skeletal muscle of the OLETF rat |
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67 | (6) |
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73 | (6) |
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Antiobese and antidiabetic effects of β3-adrenergic receptor agonist in OLETF rats |
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79 | (8) |
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Disrupted cholecystokinin type-A receptor gene in OLETF rats |
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87 | (12) |
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Alteration in hepatic enzymes involved in glucoregulation in OLETF rats |
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99 | (6) |
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What is the primary event for development of diabetes mellitus in OLETF rats? |
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105 | (8) |
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| Diabetic complications |
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Diabetic nephropathy in the OLETF rat |
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113 | (8) |
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Nerve function and blood flow in Otsuka Long-Evans Tokushima Fatty rats: effect of sucrose administration and an anticoagulant treatment |
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121 | (8) |
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Biochemical and electrophysical alterations in the OLETF rat retina |
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129 | (12) |
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Characteristics of diabetes cardiac and renal complications in the OLETF rat |
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141 | (8) |
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Molecular mechanism of hyperlipidemia in the OLETF rat |
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149 | (12) |
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| Miscellaneous physical features in the OLETF rat |
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Why does a female OLETF rat not become diabetic? Sexual dimorphism regarding the incidence of diabetes mellitus in the OLETF rat |
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161 | (10) |
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Alterations in pancreatic exocrine functions in OLETF rats |
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171 | (12) |
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Gut hyperabsorption of glucose as a cause of postprandial hyperglycemia in OLETF rats |
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183 | (8) |
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Behavior abnormalities in the OLETF rat |
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191 | (10) |
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| Treatment |
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Are caloric restriction and exercise training effective in preventing diabetes mellitus in the OLETF rat? |
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201 | (8) |
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Does metformin or troglitazone ameliorate insulin resistance and lower blood pressure in OLETF rats? |
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209 | (6) |
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Effects of aminoguanidine on diabetic nephropathy in the OLETF rat |
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215 | (8) |
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Effects of an aldose reductase inhibitor on diabetic nephropathy in the OLETF rat |
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223 | (8) |
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Effects of exercise training and food restriction on endothelial function in OLETF rats |
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231 | (6) |
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Similarity and dissimilarity between the OLETF rats and obese subjects with NIDDM |
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237 | (8) |
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| Index of authors |
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245 | (2) |
| Keyword index |
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247 | |
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