| Contributing Authors |
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xi | |
| Foreword to the First Edition |
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xix | |
| Preface |
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xxi | |
| Color Plates fall between pages 478 and 479 |
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| Section I Strategies for the Use of Agents at High Dose |
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Pharmacologic Strategies for High-Dose Therapy |
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3 | (12) |
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Preclinical Models for High-Dose Therapy |
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15 | (34) |
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49 | (20) |
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What Is the Best Strategy for Autologus Hematopoietic Stem Cell Transplantation in Cancer? |
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69 | (8) |
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Strategies for the Use of Total-Body Irradiation as Stemic Therapy in Hematologic Malignancies |
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77 | (32) |
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109 | (14) |
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Immune Adjuvant Therapy Post High-Dose Therapy |
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123 | (16) |
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A Health Policy Perspective on High-Dose Cancer Therapy: Cost, Effectiveness, and Cost-Effectiveness |
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139 | (14) |
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Quality of Life after Bone Marrow Transplantation |
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153 | (14) |
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167 | (18) |
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| Section II Reestablishing Hematopoiesis after Dose-Intensive Therapy Transplantation |
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The Hematopoietic Microenvironment |
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185 | (8) |
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Hematologic Reconstitution after Allogeneic Hematopoietic Cell Transplantation |
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193 | (18) |
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Allogeneic Core Blood Hematopoietic Stem Cell Transplants in Malignancies |
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211 | (10) |
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Bone Marrow Transplantation Using Unrelated Donors |
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221 | (22) |
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Autologous Bone Marrow Transplantation |
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243 | (30) |
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Reestablishing Hematopoiesis with Peripheral Stem Cells |
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273 | (10) |
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Immunologic Reconstitution after High-Dose Chemoradiotherapy and Allogeneic of Autologus Bone Marrow or Peripheral Blood Hematopoietic Stem Cell Transplantation |
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283 | (18) |
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| Marrow Contamination |
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Minimal Disease: Detection and Significance |
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301 | (30) |
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Negative and Positive Stem Cell Selection |
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331 | (24) |
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Stem Cell In Vitro Purging for Autologous Transplantation |
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355 | (38) |
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| Growth Factors |
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Granulocyte-Macrophage Colony-Stimulating Factor |
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393 | (18) |
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Recombinant Human Granulocyte Colony-Stimulating Factor Support of Cancer Patient |
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411 | (26) |
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437 | (18) |
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The Biology and Clinical Use of Stem Cell Factor |
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455 | (12) |
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Other Cytokines (IL-11, Thrombopoietin, flt-3 Ligand, and IL-3) |
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467 | (12) |
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| Section III Laboratory and Clinical Support for Dose-Intensive Therapy |
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The American Society of Clinical Oncology and American Society of Hematology Recommended Criteria for the Performance of Bone Marrow Transplantation |
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479 | (2) |
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Nursing for Patients Receiving High-Dose Chemotherapy with Hematopoietic Rescue |
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481 | (14) |
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495 | (16) |
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Blood Bank Support for Patients Undergoing High-Dose Chemotherapy |
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511 | (24) |
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Infectious Complications after High-Dose Chemotherapy |
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535 | (22) |
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557 | (18) |
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Hepatic Complications of Bone Marrow Transplantation |
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575 | (20) |
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Cardiovascular System and High-Dose Therapy |
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595 | (14) |
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Multiple Organ Dysfunction Syndrome |
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609 | (16) |
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625 | (16) |
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Genitourinary, Gastrointestinal, Endocrine, Nervous System, and Coagulation Complications |
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641 | (8) |
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649 | (18) |
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| Section IV Clinical Applications of High-Dose Therapy |
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High-Dose Therapy in Acute Myeloid Leukemia |
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667 | (24) |
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High-Dose Therapy in Acute Lymphoblastic Leukemia |
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691 | (14) |
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Chronic Myelogenous Leukemia |
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705 | (28) |
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Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia |
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733 | (10) |
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High-Dose Therapy in Multiple Myeloma |
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743 | (12) |
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High-Dose Therapy for Hodgkin's Disease |
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755 | (20) |
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High-Dose Therapy for the Treatment of Non-Hodgkin's Lymphoma |
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775 | (22) |
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High-Dose Therapy in Burkitt's Lymphoma |
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797 | (10) |
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High-Dose Chemotherapy in Patients with Germ Cell Cancer |
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807 | (14) |
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Dose-Intensive Therapy for Breast Cancer |
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821 | (20) |
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841 | (12) |
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High-Dose Chemotherapy and Stem Cell Transplantation for Ovarian Cancer |
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853 | (18) |
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High-Dose Therapy and Stem Cell Transplantation for Neuroblastoma and Other Pediatric Solid Tumors |
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871 | (24) |
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895 | (14) |
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909 | (12) |
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| Index |
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921 | |