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An Introduction to Epidemiology,9780763700607
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An Introduction to Epidemiology


Author(s): Timmreck, Thomas C.
ISBN10:  0763700606
ISBN13:  9780763700607
Format:  Paperback
Pub. Date:  4/1/2002
Publisher(s): Jones & Bartlett

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Table of Contents
About the Author vi
Preface xv
Preface to the Third Edition xvii
Foreword xix
Foundations of Epidemiology
1(26)
Objectives
1(1)
Introduction
2(1)
Epidemiology Defined
2(1)
Epidemiologist Defined
3(1)
Purposes of Epidemiology
3(1)
Scope and Application of Epidemiology
4(1)
Incidence and Prevalence Described
5(1)
Uses of Epidemiology
5(1)
The Epidemiology Triangle
6(3)
Some Disease Transmission Concepts
9(2)
Modes of Disease Transmission
11(1)
The Chain of Infection
12(2)
NEWS FILE: Pediculosis (Person-to-Person Transmission)
13(1)
Classes of Epidemics/Outbreaks
14(1)
The Advanced Triangle of Epidemiology
15(1)
Goals of Epidemiology
16(1)
Case Concepts in Epidemiology
16(2)
Levels of Prevention
18(3)
Conclusion
21(1)
Exercises
22(3)
References
25(2)
Practical Disease Concepts in Epidemiology
27(44)
Objectives
27(1)
Introduction
28(1)
Essentials of Communicable Disease
28(2)
The Natural Course of Disease
30(2)
General Classification of Diseases
32(3)
Classification of Disease by Cause
35(1)
Inanimate Sources of Illness and Disability
36(1)
Portals of Entry of Infectious Disease Agents into the Human Body
37(1)
Time: Incubation Periods in Communicable Diseases
37(3)
Zoonosis
40(2)
International Classification of Diseases
42(2)
Notifiable Diseases in the United States (Centers for Disease Control and Prevention)
44(3)
Immunizations: Protecting the Public from Disease
47(2)
Herd Immunity
49(3)
Communicable Disease Prevention and Control
52(6)
NEWS FILE: Disease Transmission and Universal Precautions
57(1)
Noncommunicable Diseases and Chronic Disease Classification
58(2)
Nutritional Deficiency Diseases and Disorders
60(1)
Chronic Diseases and Conditions
61(4)
Health Goals for the Year 2010
65(1)
Exercises
66(3)
References
69(2)
Selected Historical Developments of Epidemiology
71(26)
Objectives
71(1)
Introduction
72(1)
Hippocrates, the First Epidemiologist
72(1)
Disease Observations of Sydenham
73(1)
The Epidemiology of Scurvy in 1753
74(1)
Cowpox and Its Epidemiological Connection to Smallpox
75(1)
The Epidemiology of Childbed Fever in a Lying-in Hospital
76(1)
Historical Epidemiological Assessment of Cholera in London
77(4)
NEWS FILE: Cholera Epidemic
80(1)
Pasteur's and Koch's Contribution to Epidemiology
81(1)
The Microscope and Its Contribution to Epidemiology
82(1)
John Graunt and Vital Statistics Development
83(1)
Ramazzini and the Epidemiology of Occupational Health and Industrial Hygiene
84(2)
Typhoid Mary
86(1)
The Epidemiology of Vitamins in Curing Nutritional Diseases
86(1)
The Beginning of Epidemiology in the United States (1793-1913)
87(2)
Historical Developments of Morbidity in Epidemiology
89(1)
The Tuskegee Syphilis Study
90(2)
The Framingham Heart Study
92(1)
The Epidemiology of Cigarette Smoking and Cancer
93(1)
Exercises
94(1)
References
95(2)
Epidemiological Measures of Health Status: Mortality-Rates and Ratios
97(36)
Chapter Objectives
97(1)
Introduction
98(1)
Mortality Statistics
98(1)
Rates
99(4)
Ratios
103(1)
Proportions
104(1)
Mortality
105(5)
NEWS FILE: Top Causes of Death Worldwide
110(1)
Three Levels of Rates (General Use)
110(1)
Types of Mortality Rates/Ratios
111(2)
Infant Mortality
113(6)
Abortion
119(1)
Maternal Mortality Rates
119(2)
Adjusted Death Rates
121(6)
Mortality Crossover
127(1)
Mortality Time Trends
127(1)
Years of potential Life Lost (YPLL)
128(1)
Exercises
129(2)
References
131(2)
Epidemiological Measures of Health Status: Morbidity-Rates and Ratios
133(38)
Objectives
133(1)
Introduction
134(1)
Incidence and Incidence Rates
134(3)
Approaches to Incidence Rates
137(1)
Some Fundamental Concepts of Incidence
138(2)
CASE FILE: Rubella (Incidence of Disease)
140(1)
Risk in Morbidity
140(1)
Relative Risk
141(6)
Incidence and Attack Rates
147(4)
Prevalence
151(5)
CASE FILE: Pingpong Gonorrhea (Recurring Diseases)
155(1)
Epidemics: Two Types-Common Source and Propagated
156(3)
Odds Ratio
159(3)
NEWS FILE: Hantavirus (Emerging Infections)
160(2)
Formalized Sources of Morbidity Statistics and Data
162(5)
Exercises
167(2)
References
169(2)
Epidemiology Vital Statistics and Health Status Indicators
171(32)
Objectives
171(1)
Introduction
172(1)
Census of the Population
173(4)
Standard Metropolitan Statistical Area (SMSA)
177(1)
Vital Events Registration
178(2)
Birth Rate and Crude Birth Rate
180(1)
Mortality and Death Certificates in Vital Statistics
180(2)
The Role of the Medical Examiner and Coroner
182(1)
Marriage and Divorce Statistics
183(1)
Computer Use in Vital Statistics and Epidemiology
184(1)
Selected Sources of Data for Epidemiological and Vital Statistics Information
185(13)
Private Professional Associations as Sources of Data
198(2)
Exercises
200(1)
References
201(2)
Descriptive Statistics in Epidemiology
203(28)
Chapter Objectives
203(1)
Introduction
204(1)
Computers in Epidemiological Descriptive Statistics
204(1)
Descriptive Statistics Basics
205(3)
NEWS FILE: AIDS/HIV (Epidemics, Prevalence, Prevention, and Control)
207(1)
Types and Sources of Data for Descriptive Statistics
208(2)
Parametric and Nonparametric Data
210(1)
Central Tendency
211(1)
Skewness of Standard Distribution Bell Curve
212(2)
Tables and the Presentation of Data in Epidemiology
214(1)
Graphs and Charts in the Presentation of Descriptive Statistics Data
215(5)
Rates, Ratios, and Proportions in Epidemiology
220(1)
Samples of Tables and Charts Used in Epidemiological Reports
220(7)
Exercises
227(2)
References
229(2)
Research Methods, Study Design, and Analytic Studies
231(44)
Objectives
231(1)
Introduction
232(1)
Observational Epidemiology Studies
232(1)
Descriptive vs Analytical Epidemiological Studies
233(1)
The Study Designs
234(1)
Experimental/Analytical Design in Epidemiology
235(1)
Observational Studies
236(8)
CASE FILE: Data Collection in Case Control Studies
238(5)
CASE FILE: Retrospective and Outcome Studies
243(1)
Cross-Sectional Studies/Survey Research
244(5)
Selection of Study Population
249(1)
Surveys in Cross-Sectional Studies
250(1)
Five Data Gathering Approaches
251(1)
Sampling the Population for Epidemiological Studies
252(4)
National Epidemiological Health Survey Methodology
256(2)
Prospective Studies/Longitudinal Studies
258(3)
Cohorts and Cohort Studies
261(5)
Survivorship Studies in Epidemiology
266(2)
Pretest/Intervention/Post-Test Design
268(1)
Ethics in Research
269(1)
Conclusion
269(1)
Exercises
270(2)
References
272(3)
Time, Place, and Person
275(62)
Objectives
275(1)
Introduction
276(1)
Time
276(11)
Time Clustering
287(4)
Place
291(5)
Maps and Spot/Dot Maps in Epidemiology
296(10)
Use of Building Maps in Epidemiology
306(7)
NEWS FILE: Mapping in Epidemiology
311(2)
Zoonosis
313(1)
Person
314(7)
Sex
321(2)
Race and Ethnicity
323(3)
Marital and Family Status
326(2)
Family Structure and Genealogical Research
328(1)
Occupation
328(1)
Education as a Characteristic of the Person
329(4)
Exercises
333(2)
References
335(2)
Observational Methodology, Association, and Causality Development
337(36)
Objectives
337(1)
Introduction
338(1)
Causality in Epidemiology
338(4)
Prevention and Control Approaches Derived from Causation
342(1)
Factors in Causation of Disease
342(2)
Webs of Causation
344(5)
Epidemiological Association in Causation of Disease
349(5)
Hypothesis Development for Epidemiology
354(2)
Analytical Epidemiology
356(5)
Risk in Association and Causality
361(1)
Screening and Disease Detection in Populations
362(2)
Sensitivity and Specificity: Tests of Validity
364(6)
Exercises
370(1)
References
371(2)
Developing and Conducting Investigations and Studies
373(18)
Objectives
373(1)
Introduction
374(1)
Planning and Administration of Epidemiological Studies
374(1)
Working Up an Epidemiology Study
375(1)
Steps in an Epidemiology Investigation
375(7)
NEWS FILE: Disease Investigation and Control
382(1)
Setting Up a Cohort Occupational Epidemiology Study
382(2)
Steps in Working up a Foodborne Illness Investigation
384(1)
Basic Epidemiological Questions
385(3)
Exercises
388(2)
References
390(1)
Behavioral and Chronic Disease Epidemiology
391(26)
Chapter Objectives
391(1)
Introduction
392(1)
Chronic Disease Epidemiology
392(3)
Risk Factors in Chronic Diseases and Behaviorally Caused Diseases
395(1)
Odds Ratio in Chronic Diseases
396(1)
NEWS FILE: Teenage Smoking (Behavioral Epidemiology)
397(1)
Developing Webs of Causation for Chronic Diseases or Behaviorally Caused Disorders
397(6)
Chronic Disease, Behaviorally Caused, and Noncommunicable Disease Epidemiological Studies (Some Examples)
403(7)
Prevention and Control: A Hallmark of Epidemiology
410(1)
Quality of Adjusted Life Years/Healthy People 2000
410(1)
Priorities for Prevention and Health Promotion Activities Related to Epidemiology
411(1)
Health Belief Model in Chronic Disease Epidemiology
412(2)
Exercises
414(1)
References
415(2)
Appendix I Case Studies 417(72)
Case Study No. I Snow on Cholera
419(1)
(A) Cholera-Examples, Cases, and Observations
419(4)
Case Study Questions
423(1)
(B) Cholera and the Broad Street Pump Outbreak
424(7)
Case Study Questions
431(1)
(C) Cholera Epidemic of 1853 and Two London Water Companies
431(2)
Cholera Epidemic of 1854
433(2)
Case Study Questions
435(3)
(D) Epidemiological Issues
438(3)
Case Study Questions
441(2)
Case Study No. II Working through a Foodborne Illness Epidemic Investigation: Typhoid Fever in Schenectady
443(1)
Case of Typhoid Fever in Schenectady, New York
444(1)
Case Study Questions
444(7)
Case Study No. III Common-Source Outbreak of Waterborne Shigellosis at a Public School
451(1)
Case of Common-Source Outbreak of Waterborne Shigellosis at a Public School
451(5)
Case Study Questions
456(3)
Case Study No. IV Retrospective Analysis of Occupation and Alcohol-Related Mortality
459(1)
Case of Occupation and Alcohol-Related Causes of Death, California
459(3)
Case Study Questions
462(1)
Case Study No. V Retrospective Cohort Study of the Association of Congenital Malformations and Hazardous Waste
463(1)
Case on Congenital Malformations Associated with Proximity to Hazardous Waste Sites
464(4)
Case Study Questions
468(3)
Case Study No. VI History and Epidemiology of polio Epidemics
471(1)
(A) Brief Review of poliomyelitis as It Is Known Today
472(1)
Case Study Questions
473(1)
(B) First Polio Epidemics Studied and Reported: Sweden
473(6)
Case Study Questions
479(1)
(C) First Major Epidemic of poliomyelitis in America: Rutland, Vermont
480(1)
Case Study Questions
481(1)
(D) Simon Flexner, M.D. and Wade Hamilton Frost, M.D.: American Epidemiologists Who Investigated Poliomyelitis
481(4)
Case Study Questions
485(1)
(E) Poliomyelitis Epidemic in Los Angeles, 1934
486(1)
Case Study Questions
487(1)
Epilogue
487(1)
References
488(1)
Appendix II Epidemiological Associations and Societies 489(2)
Appendix III Epi Info and Epi Map Epidemiology Software 491(4)
EPI Info
491(1)
EPI Map
492(3)
Appendix IV Internet Sites 495(2)
Index 497

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