| Preface |
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iii | |
| Contributors |
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xi | |
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Human Immunodeficiency Virus Prevention: Applying the Lessons Learned |
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1 | (22) |
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Intervention Strategies: Levels of Interventions |
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4 | (9) |
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13 | (3) |
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What Can We Recommend Now? |
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16 | (1) |
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17 | (6) |
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17 | (6) |
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Novel Strategies Toward the Development of an Effective Vaccine to Prevent Human Immunodeficiency Virus Infection or Acquired Immunodeficiency Virus |
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23 | (40) |
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How AIDS Vaccine Strategies Have Evolved from Sterilizing Immunity to the Control of Infection |
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25 | (4) |
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Live Attenuated Vaccines: Concepts to Learn |
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29 | (1) |
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30 | (13) |
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Conclusions and Perspectives |
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43 | (20) |
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46 | (17) |
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Pediatric Human Immunodeficiency Virus Type 1 Infection: Updates on Prevention and Management |
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63 | (22) |
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65 | (1) |
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Maternal and Obstetrical Factors Associated with Perinatal HIV-1 Transmission |
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66 | (9) |
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Antiretroviral Therapy for HIV-1-Infected Children |
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75 | (2) |
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77 | (8) |
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77 | (8) |
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Risk of Human Immunodeficiency Virus Infection in Health Care Workers |
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85 | (16) |
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87 | (1) |
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Anecdotal Case Reports of Occupational HIV Infection |
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88 | (3) |
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Prospective Cohort Studies |
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91 | (1) |
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92 | (2) |
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Management of Occupational Exposure |
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94 | (2) |
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HIV-Infected Health Care Workers: Risks to Patients |
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96 | (1) |
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97 | (4) |
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98 | (3) |
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Can Immune Responses to Human Immunodeficiency Virus Be Preserved, Enhanced, or Restored? |
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101 | (14) |
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103 | (1) |
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Components of Protective Immunity in HIV Infection |
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104 | (2) |
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Why Does the Immune System Fail to Control HIV? |
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106 | (1) |
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Effects of Highly Active Antiretroviral Therapy (HAART) on HIV-Specific Immune Responses |
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106 | (1) |
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Rebuilding the Immune System in Chronic HIV Infection |
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107 | (1) |
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Critical Need for Immunotherapy plus HAART in Augmenting Immunity to HIV |
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108 | (1) |
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Approaches to Immune Enhancement in HIV Infection |
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109 | (1) |
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Conclusions and Future Directions |
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110 | (5) |
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111 | (4) |
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Reconstitution of Immunity Against Opportunistic Infections in the Era of Potent Antiretroviral Therapy |
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115 | (24) |
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117 | (1) |
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118 | (5) |
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123 | (3) |
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126 | (3) |
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129 | (1) |
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130 | (1) |
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130 | (9) |
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131 | (8) |
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Salvage Therapy for Patients Failing their Current Antiretroviral Regimen |
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139 | (54) |
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141 | (3) |
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Defining Virologic Failure |
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144 | (1) |
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145 | (1) |
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146 | (4) |
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Salvage Therapy in Patients Failing PI-Containing Regimens: Clinical Trial Results |
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150 | (9) |
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Role of Intensification Strategies |
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159 | (2) |
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Predictors of Treatment Response |
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161 | (8) |
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Role of Genotypic and Phenotypic Resistance Assays in Devising Salvage Therapy |
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169 | (7) |
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Structured Treatment Interruptions |
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176 | (1) |
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Multidrug Rescue Regimens |
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177 | (2) |
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179 | (14) |
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180 | (13) |
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Drug Interactions of Antiretroviral Agents |
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193 | (36) |
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195 | (2) |
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Interpretation of Drug Concentrations |
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197 | (1) |
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197 | (1) |
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198 | (2) |
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Nucleoside Reverse Transcriptase Inhibitors |
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200 | (4) |
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204 | (5) |
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NNRTI and PI Combinations |
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209 | (5) |
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Management of Non-ARV Drug Interactions |
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214 | (6) |
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220 | (9) |
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221 | (8) |
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Rationale for Immune-Based Therapies for Human Immunodeficiency Virus Type 1 Infection |
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229 | (34) |
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Rationale for Immune-Based Therapies |
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231 | (2) |
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233 | (4) |
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Cytokines and Growth Factors |
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237 | (5) |
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Enhancement of HIV-1 Specific Immune Responses |
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242 | (7) |
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249 | (14) |
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250 | (13) |
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Human Immunodeficiency Virus and Hepatitis B and C Coinfection: Pathogenic Interactions, Natural History, and Therapy |
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263 | (44) |
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265 | (1) |
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266 | (4) |
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270 | (16) |
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286 | (21) |
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286 | (21) |
| Index |
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307 | |