| Preface |
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xi | |
| PART I THE NATURE OF CANCER |
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1 | (36) |
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3 | (12) |
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3 | (3) |
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The Critical Question: Is It Benign or Malignant? |
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6 | (1) |
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7 | (1) |
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The Different Kinds of Cancer |
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7 | (3) |
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10 | (2) |
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12 | (2) |
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14 | (1) |
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The Development of Cancer |
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15 | (11) |
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Tumor Iitiation and Progression: The Evolution of Cancer |
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15 | (4) |
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Invasion and Metastasis: The Critical Steps in Tumor Development |
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19 | (4) |
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The Immune System: A Natural Defense against Cancer |
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23 | (1) |
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Clinical Staging of Cancer |
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24 | (1) |
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25 | (1) |
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How Cancer Cells Differ from Normal Cells |
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26 | (11) |
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Control of Normal Cell Behavior |
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26 | (4) |
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Abnormal Growth of Cancer Cells |
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30 | (1) |
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The Invasiveness and Metastatic Potential of Cancer Cells |
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31 | (2) |
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Defective Differentiation and Immortality |
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33 | (1) |
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Genetic Instability and Tumor Progression |
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34 | (2) |
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36 | (1) |
| PART II CAUSES OF CANCER |
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37 | (60) |
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Cancer and the Environment |
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39 | (23) |
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How Chemicals Cause Cancer |
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39 | (2) |
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The Importance of Environmental Factors in Cancer Risk |
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41 | (1) |
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42 | (4) |
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46 | (2) |
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48 | (2) |
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50 | (6) |
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Medicines that Cause Cancer |
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56 | (1) |
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57 | (1) |
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58 | (3) |
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61 | (1) |
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Viruses, Cancer, and AIDS |
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62 | (10) |
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Hepatitis B Virus and Liver Cancer |
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63 | (1) |
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Papillomaviruses and Cervical Cancer |
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64 | (2) |
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Epstein-Barr Virus, the Immune System, and Lymphomas |
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66 | (2) |
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Human T-Cell Leukemia Viruses |
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68 | (2) |
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70 | (1) |
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71 | (1) |
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72 | (10) |
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72 | (6) |
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Genetic Diseases that Predispose to Cancer |
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78 | (1) |
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Familial Susceptibility to Cancer |
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79 | (2) |
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81 | (1) |
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Genetic Changes in Cancer Cells |
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82 | (15) |
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83 | (3) |
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86 | (3) |
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Multiple Genetic Changes Contribute to Cancer Development |
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89 | (5) |
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94 | (3) |
| PART III CANCER PREVENTION AND TREATMENT |
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97 | (58) |
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Prospects for Cancer Prevention |
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99 | (15) |
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99 | (1) |
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100 | (1) |
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101 | (1) |
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102 | (3) |
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Occupational and Medicinal Carcinogens |
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105 | (1) |
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106 | (1) |
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The Possibility of Chemoprevention |
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107 | (3) |
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The Questionable Importance of Synthetic Chemicals in the Environment |
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110 | (2) |
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112 | (2) |
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Early Detection and Diagnosis |
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114 | (13) |
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The Pap Smear and Cervical Cancer |
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115 | (1) |
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Early Detection of Breast Cancer |
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115 | (4) |
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Screening for Colorectal Cancer |
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119 | (2) |
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Early Detection of Other Cancers |
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121 | (1) |
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122 | (1) |
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122 | (4) |
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126 | (1) |
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127 | (18) |
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127 | (2) |
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129 | (1) |
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130 | (3) |
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Drug Resistance and Combination Chemotherapy |
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133 | (2) |
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Bone Marrow Transplantation |
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135 | (1) |
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136 | (3) |
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139 | (2) |
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Clinical Trials versus Unproven Treatments |
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141 | (2) |
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143 | (2) |
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145 | (10) |
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Dealing with the Diagnosis of Cancer |
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145 | (1) |
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Cancer Treatments and Their Side Effects |
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146 | (3) |
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149 | (1) |
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150 | (1) |
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Surviving Cancer: Will It Come Back? |
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151 | (1) |
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151 | (1) |
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152 | (1) |
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153 | (2) |
| PART IV OVERVIEW OF MAJOR TYPES OF CANCER |
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155 | (40) |
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157 | (11) |
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Acute Lymphocytic Leukemia |
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159 | (2) |
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Acute Nonlymphocytic Leukemias |
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161 | (1) |
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Chronic Lymphocytic Leukemia |
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162 | (1) |
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Chronic Myelogenous Leukemia |
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163 | (1) |
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163 | (1) |
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164 | (3) |
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167 | (1) |
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167 | (1) |
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168 | (6) |
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169 | (1) |
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169 | (1) |
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170 | (1) |
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170 | (2) |
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172 | (1) |
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172 | (1) |
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173 | (1) |
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Common Solid Tumors of Adults |
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174 | (21) |
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174 | (2) |
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176 | (3) |
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179 | (2) |
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181 | (1) |
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182 | (2) |
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184 | (2) |
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186 | (1) |
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187 | (1) |
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Melanoma and Other Skin Cancers |
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187 | (1) |
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188 | (1) |
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189 | (1) |
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190 | (1) |
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190 | (1) |
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191 | (1) |
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191 | (1) |
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192 | (1) |
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192 | (1) |
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193 | (2) |
| PART V PROSPECTS FOR THE FUTURE |
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195 | (8) |
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The War on Cancer---Progress and Promises |
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197 | (6) |
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Progress in Cancer Prevention and Treatment |
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198 | (2) |
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Progress in Understanding Cancer |
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200 | (1) |
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The Future's Promise: Will Our Understanding of Cancer Yield Practical Benefits? |
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201 | (1) |
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202 | (1) |
| Appendix: Information and Resources for Cancer Patients |
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203 | (9) |
| Glossary |
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212 | (12) |
| Further Reading |
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224 | (5) |
| Index |
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229 | |
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