9780941451932

Foreword

Preface

xiii

Genetics 101: The Basics of Inheritance

(1)

Identifying Genotype

(1)

Understanding Genetics

(2)

The Genetics of Disease

(4)

DNA---The Fabric of Life

(6)

Genetic Counseling

(7)

Application for Veterinarians

(6)

The Future

(2)

Cardiovascular System Disorders

(10)

Aortic Stenosis

(1)

Atrial Septal Defect

(1)

Cardiomyopathy

(3)

Chronic Mitral Valvular Disease (Endocardiosis)

(1)

Femoral Artery Occlusion

(1)

Hypertension

(1)

Patent Ductus Arteriosus (PDA)

(1)

Pulmonic Stenosis

(1)

Sick Sinus Syndrome

(1)

Tetralogy of Fallot

(1)

Tricuspid Valve Dysplasia

(1)

Vascular Ring Anomalies

(1)

Ventricular Ectopy

(1)

Ventricular Septal Defect

(2)

Dental Disorders

(6)

Brachygnathism

(1)

Malocclusion

(1)

Missing Teeth

(1)

Polydontia

(1)

Prognathism

(3)

Dermatologic Conditions

(20)

Acanthosis Nigricans

(1)

Acquired Aurotrichia

(1)

Acral Lick Dermatitis

(1)

Acral Mutilation Syndrome

(1)

Albinism

(1)

Anasarca

(1)

Calcinosis Circumscripta

(1)

Collagenolytic Granuloma

(1)

Color-Dilution Alopecia

(1)

Congenital Hypotrichosis

(1)

Cutaneous Asthenia

(1)

Dalmatian Bronzing Syndrome

(1)

Demodectic Mange

(1)

Dermatomyositis

(1)

Dermoid Sinus

(1)

Ectodermal Defect

(1)

Epidermal Dysplasia

(1)

Epidermolysis Bullosa (EB)

(1)

Familial Benign Pemphigus

(1)

Familial Vasculopathy

(1)

Fold Dermatitis

(1)

Follicular Dysplasia

(2)

Greyhound Alopecia

(1)

Ichthyosis

(1)

Juvenile Cellulitis

(1)

Lentigo

(1)

Lethal Acrodermatitis

(1)

Lichenoid-Psoriasiform Dermatitis

(1)

Lupoid Dermatosis

(1)

Lupoid Onychopathy

(1)

Malassezia Dermatitis

(1)

Malignant Histiocytosis

(1)

Mucinosis

(1)

Nodular Dermatofibrosis

(1)

Panniculitis

(1)

Perianal Fistulae

(1)

Schnauzer Comedo Syndrome

(1)

Sebaceous Adenitis

(1)

Seborrhea

(1)

Spiculosis

(1)

Ulcerative Dermatosis

(1)

Vitamin A-Responsive Dermatosis

(1)

Vitiligo

(1)

X-Linked Ectodermal Dysplasia

(1)

Zinc-Responsive Dermatosis

(2)

Endocrine Disorders

(8)

Adrenal Sex-Hormone Dermatoses

(1)

Diabetes Mellitus

(2)

Growth Hormone-Responsive Dermatoses

(1)

Hyperadrenocorticism (Cushing's Syndrome)

(1)

Hyperparathyroidism

(1)

Hypoadrenocorticism (Addison's Disease)

(1)

Hypothyroidism

(1)

Pituitary Dwarfism (Hypopituitarism)

(1)

Recurrent (Seasonal) Flank Alopecia

(2)

Gastrointestinal Disorders

(8)

Chronic Inflammatory Hepatic Disease

(1)

Cleft Palate/Cleft Lip

(1)

Colitis

(1)

Copper Hepatopathy

(1)

Esophageal Motility Disorders

(1)

Exocrine Pancreatic Insufficiency

(1)

Gastric Dilatation-Volvulus (Bloat)

(1)

Gluten-Sensitive Enteropathy

(1)

Immunoproliferative Enteropathy

(1)

Pancreatitis

(1)

Portosystemic Shunts

(1)

Protein-Losing Enteropathy

(1)

Pyloric Stenosis

(1)

Small Intestinal Bacterial Overgrowth (SIBO)

(1)

Hemolymphatic Disorders

(12)

Cutaneous and Renal Glomerular Vasculopathy

(1)

Factor I Deficiency

(1)

Factor II Deficiency

(1)

Factor VII Deficiency

(1)

Factor VIII Deficiency (Hemophilia A)

(1)

Factor IX Deficiency (Hemophilia B)

(1)

Factor X Deficiency

(1)

Factor XI Deficiency

(1)

Factor XII Deficiency

(1)

Hereditary Macrocytosis/Stomatocytosis

(1)

Hereditary Nonspherocytic Hemolytic Anemia

(1)

Methemoglobin Reductase Deficiency

(1)

Lymphedema

(1)

Microcytosis

(1)

Pelger-Huet (PH) Anomaly

(1)

Prekallikrein Deficiency

(1)

Psedohyperkalemia

(1)

Pyruvate Kinase Deficiency

(1)

Thrombopathy

(1)

Thrombasthenic Thrombopathia

(1)

Vasculitis

(1)

Von Willebrand Disease (vWD)

(4)

Immunologic Disorders

(8)

Allergic Inhalant Dermatitis (Atopy)

(1)

Chinese Shar Pei Immunodeficiency

(1)

Complement (C3) Deficiency

(1)

Cyclic Hematopoiesis

(1)

German Shepherd Dog Pyoderma (GSP)

(1)

Leukocyte Adhesion Deficiency

(1)

Lupus Erythematosus

(1)

Lupus Erythematosus (Systemic)

(1)

Lupus Ertyhematosus (Cutaneous)

(1)

Mycobacterial Susceptibility

(1)

Neutrophil Bactericidal Defect

(1)

Pneumocystosis

(1)

Pemphigus

(1)

Pemphigoid

(1)

Primary Ciliary Dyskinesia

(1)

Selective Immunoglobulin A (IgA) Deficiency

(1)

Thymic Atrophy of Mexican Hairless Dogs

(1)

Uveodermatologic Syndrome

(1)

Weimaraner Immunodeficiency

100

(1)

X-Linked Severe Combined Immunodeficiency

100

(1)

Metabolic Disorders

101

(10)

Amyloidosis

101

(1)

Ceroid Lipofuscinosis

102

(1)

Cholesterol Ester Storage Disease

102

(1)

Fucosidosis

103

(1)

Galactosialidosis

103

(1)

Globoid Cell Leukodystrophy (GCL)

103

(1)

Glucocerebrosidosis (Gaucher's Disease)

104

(1)

Glycogen Storage Disease Type Ia

104

(1)

Glycogen Storage Disease Type II

105

(1)

Glycogen Storage Disease Type III

105

(1)

GM-1 Gangliosidosis

105

(1)

GM-2 Gangliosidosis

106

(1)

Hyperlipidemia

106

(1)

Hyperphosphatemia

106

(1)

Lafora-Body Disease

106

(1)

Malignant Hyperthermia

107

(1)

Mucopolysaccharidosis I

107

(1)

Mucopolysaccharidosis II

107

(1)

Mucopolysaccharidosis IIIA

107

(1)

Mucopolysaccharidosis VI

108

(1)

Mucopolysaccharidosis VII

108

(1)

Phosphofructokinase Deficiency

108

(1)

Niemann-Pick Diseases (Sphingomyelinosis)

109

(1)

Selective Malabsorption of Vitamin B12

109

(1)

Tyrosinemia

109

(2)

Musculoskeletal Disorders

111

(18)

Abdominal Hernias

111

(1)

Bouvier des Flandres Myopathy

111

(1)

Cranial Cruciate Ligament Rupture

112

(1)

Craniomandibular Osteopathy

112

(1)

Elbow Dysplasia

113

(2)

Gracilis or Semitendinosis Myopathy

115

(1)

Hereditary Myopathy

115

(1)

Hip Dysplasia

116

(4)

Hypertrophic Osteodystrophy

120

(1)

Idiopathic Multifocal Osteopathy

120

(1)

Legg-Calve-Perthes Disease

120

(1)

Masticatory Myositis

121

(1)

Mitochondrial Myopathy

121

(1)

Muscular Dystrophy

121

(1)

Myoclonus

122

(1)

Myositis Ossificans

122

(1)

Myotonia

122

(1)

Osteochondrosis

122

(2)

Osteochondrosis of the Shoulder

124

(1)

Osteochondrosis of the Hindlegs

124

(2)

Osteochondrodysplasia

126

(1)

Osteogenesis Imperfecta

126

(1)

Panosteitis

126

(1)

Patellar Luxation

127

(2)

Nervous System Disorders

129

(18)

Aggression

129

(1)

Cerebellar Abiotrophy

129

(1)

Cerebellar Ataxia

130

(1)

Cerebellar Hypoplasia

130

(1)

Cervical Vertebral Instability

130

(1)

Compulsive Behaviors

131

(1)

Congenital Peripheral Vestibular Disease

132

(1)

Deafness

132

(1)

Degenerative Myelopathy

133

(1)

Dysmyelinogenesis

134

(1)

Hemivertebra

135

(1)

Hydrocephalus

135

(1)

Intervertebral Disk Disease (IVD)

136

(1)

Leukodystrophies

137

(1)

Lissencephaly

138

(1)

Meningitis

138

(1)

Myasthenia Gravis (MG)

139

(1)

Myelodysplasia

140

(1)

Neuroaxonal Dystrophies

140

(1)

Peripheral Neuropathies

141

(1)

Rage Syndrome

142

(1)

Sacrocaudal Dysgenesis

142

(1)

Scotty Cramp

142

(1)

Seizure Disorders

143

(1)

Shaker Syndrome

144

(1)

Sleep Disorders

144

(1)

Spina Bifida

145

(1)

Spinal Muscular Atrophy

145

(1)

Vertebral Stenosis

146

(1)

Ophthalmologic Disorders

147

(26)

Cataracts

147

(1)

Collie Eye Anomaly

147

(3)

Corneal Dystrophy

150

(1)

Dermoid

151

(1)

Distichiasis

151

(2)

Ectropion

153

(1)

Entropion

154

(1)

Glaucoma

154

(1)

Hemeralopia

154

(2)

Keratoconjunctivitis Sicca (KCS)

156

(2)

Lens Luxation

158

(1)

Microphthalmia

158

(1)

Optic Nerve Colobomas

159

(1)

Optic Nerve Hypoplasia and Micropapilla

159

(1)

Pannus

159

(2)

Persistent Primary Vitreous

161

(1)

Persistent Pupillary Membranes

162

(1)

Progressive Retinal Atrophy, Central (CPRA)

162

(1)

Progressive Retinal Atrophy, Generalized (PRA)

163

(5)

Prolapsed Gland of the Nictitans (Cherry Eye)

168

(1)

Retinal Dysplasia

168

(3)

Stationary Night Blindness

171

(1)

Uveal Hypopigmentation

171

(2)

Reproductive Problems

173

(4)

Cryptorchidism

173

(1)

Abnormalities in Sexual Differentiation

174

(3)

Respiratory Disorders

177

(2)

Brachycephalic Syndrome

177

(1)

Hypoplastic Trachea

177

(1)

Laryngeal Paralysis

177

(1)

Tracheal Collapse

178

(1)

Urinary System Disorders

179

(8)

Congenital Renal Disease

179

(2)

Fanconi Syndrome

181

(1)

Immunune-Mediated Glomerulonephritis

181

(1)

Primary Renal Glucosuria

182

(1)

Urolithiasis

182

(5)

Appendix The Major Players

187

(6)

Breed Table

193

(52)

References

245

(24)

Index

269

(10)

About the Author

279

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Genetic Connection : A Guide to Health Problems in Purebred Dogs

0941451933

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