| Something Old, Something New A general overview |
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Flavins, flavoproteins and flavoproteomics |
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3 | (10) |
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Studies of the mechanisms of bacterial and mammalian methylentetrahydrofolate reductases |
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13 | (10) |
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Hmp: a Hydra-like microbial flavohaemoglobin |
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23 | (10) |
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Crystal structure of Schizosaccharomyces pombe riboflavin kinase |
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33 | (6) |
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High resolution structure of phenol hydroxylase and correction of previous sequencing errors |
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39 | (6) |
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The crystal structure of riboflavin synthase of Schizosaccharomyces pombe in complex with 6-carboxyethyl-7-oxo-8-ribityllumazine reveals insights into the reaction mechanism |
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45 | (6) |
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Crystallographic analysis of E. coli 2,4-dienoyl CoA reductase |
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51 | (6) |
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Structural comparison of acyl-CoA oxidase-II from rat liver with medium-chain acyl-CoA dehydrogenase from pig liver |
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57 | (6) |
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Yeast acetohydroxyacid synthase. Crystal structure of an enzyme containing non-catalytic FAD |
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63 | (6) |
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The iron-sulfur flavoenzyme adenylsulfate reductase -- a comparison with structurally related flavin containing enzymes |
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69 | (8) |
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Three-dimensional structure of porcine electron transfer flavoprotein-ubiquinone oxidoreductase |
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77 | (6) |
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Preliminary crystal structure of a flavocytochrome c -- sulfide dehydrogenase (FCSD) from the halophilic phototropic sulfur bacterium, Halochromatium salexigens |
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83 | (8) |
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II. Structure / Function and Mechanism |
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Structure-function studies of glutamate synthases |
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91 | (10) |
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Trifluorolactate, a mechanistic probe for 2-hydroxy acid- oxidizing enzymes |
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101 | (8) |
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Kinetics and mechanism of the conversion of red to blue FMN flavosemiquinone |
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109 | (4) |
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Substrate specificity of rat liver NAD(P)H : quinone oxidoreductase (NQO1) |
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113 | (6) |
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The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis |
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119 | (6) |
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Kinetic mechanism of dimethylglycine oxidase |
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125 | (6) |
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Mechanism of high Mr thioredoxin reductase from Drosophila melanogaster |
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131 | (6) |
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Active site of yeast D-amino acid oxidase: mutations and interferences |
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137 | (6) |
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A balance in the active site electrostatic field is required for optimal catalysis by p-hydroxybenzoate hydroxylase: studies with the charge mutant Glu49Gln |
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143 | (6) |
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Comparative study of choline oxidizing enzymes from Escherichia coli, Halomonas elongata, and Arthrobacter globiformis |
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149 | (6) |
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Structure-function studies on fungal aryl-alcohol oxidase |
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155 | (6) |
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19F NMR ligand perturbation studies on the riboflavin synthase of Schizosaccharomyces pombe |
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161 | (6) |
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Studies on the mechanism of 3,4,-dihydroxy-2-butanone 4-phosphate synthase of the Archaeon Methanococcus jannaschii |
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167 | (8) |
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Theoretical analysis of the changes introduced in the electron spin density distribution of the neutral flavin semiquinone isoalloxine ring upon modification of the isoalloxazine ring |
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175 | (6) |
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Mechanistic studies on choline oxidase from Arthrobacter globiformis |
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181 | (6) |
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The alkanesulfonate monooxygenase system: a novel flavin transfer mechanism |
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187 | (6) |
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On the role of the 376-functional group in catalysis by medium chain acyl-CoA-dehydrogenase |
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193 | (6) |
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Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe and its unusual affinity to riboflavin |
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199 | (6) |
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Mechanistic studies of Trp-102 mutant forms of pentaerythritol tetranitrate reductase |
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205 | (6) |
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Crystallographic studies on the inactive confirmation of ferredoxin-dependent glutamate synthase |
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211 | (6) |
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Thiol reactivities as probes of MAO-A and MAO-B structure and function |
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217 | (6) |
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Single turnover kinetic analysis of riboflavin synthase from Escherichia coli |
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223 | (6) |
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Purification and characterization of recombinant 2-nitropropane dioxygenase from Hansenula mrakii and Neurospora crassa |
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229 | (6) |
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Modeling substrates in the active site of riboflavin synthase |
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235 | (6) |
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Essential zinc ions at the catalytic sites of GTP cyclohydrolases |
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241 | (6) |
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Pentaerythritol tetranitrate reductase: reaction with NADPH, steroids, 2-cyclohexanone, nitroesters and nitroaromatic explosives |
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247 | (6) |
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Mutational analysis in dimer formation of FMN-binding protein |
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253 | (6) |
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Functional studies on two single histidine mutants of Neurospora crassa chorismate synthase |
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259 | (6) |
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A spectroscopic analysis of inhibitor binding to Enterobacter cloacae nitroreductase |
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265 | (6) |
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The factor in bovine milk and the sulfhydryl residues of xanthine oxidoreductase responsible for conversion from dehydrogenase to oxidase forms |
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271 | (4) |
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The key residues for conversion of electron acceptor specificity of xanthine oxidoreductase analysed by site-directed mutagenesis |
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275 | (6) |
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Studies on 8-CHO-flavins, 8-CN-flavins and 8-CHO-flavoproteins |
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281 | (6) |
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Bacterial morphinone reductase: active site structure and properties of active site mutant enzymes |
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287 | (6) |
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A proposed electrostatic contribution to the obligate two-electron, oxygen-insensitive reactivity of enteric nitroreductase |
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293 | (6) |
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Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with β-chloro-D-alanine |
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299 | (6) |
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Structural insights into substrate binding and mechanism in flavocytochrome b2 |
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305 | (6) |
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Significance of the proton transfer network of para-hydroxybenzoate hydroxylase in the monooxygenation of substrate: pH dependence and kinetic isotope effects of several enzyme forms |
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311 | (6) |
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Towards the practical interpretation of flavin spectra |
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317 | (6) |
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Specific inhibition of a class 1A dihydroorotate dehydrogenase by benzoate analogs of pyrimidines -- a structural dilemma |
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323 | (6) |
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Resonance Raman characterization of the two-electron reduced forms of yeast glutathione reductase |
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329 | (6) |
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Yeast D-amino acid oxidase: structural basis of its catalytic properties |
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335 | (6) |
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Thermal stability of yeast D-amino acid oxidase: deconvoluting the contributions of the dimeric aggregation state |
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341 | (6) |
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Kinetic mechanism of glycine oxidase |
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347 | (6) |
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Engineering the substrate specificity of D-amino acid oxidase by rational and irrational design |
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353 | (6) |
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Identification of possible substrate-specificity determinants in NfsA, the major oxygen-insensitive nitroreductase from Escherichia coli |
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359 | (4) |
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Single turnover kinetic analysis of 6,7-dimethyl-8-ribityllumazine synthase from Bacillus subtilis |
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363 | (6) |
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Identification of a catalytic residues in tryptophan 2-monooxygenase, a homologue of L-amino acid oxidase |
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369 | (6) |
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N(5)-Cys-adduct/enzyme-FMN equilibrium and conversion of FMN to 8-formyl-FMN in the lactate monooxygenase mutant R293K from Mycobacterium smegmatis |
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375 | (6) |
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Probing the mechanism of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase by using 8-substituted-FAD analogs |
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381 | (6) |
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Cofactor-dependent assembly of the flavoprotein vanillyl alcohol oxidase |
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387 | (6) |
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Robert H.H. van den Heuvel |
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NADH oxidase concerned in hydro peroxide scavenging system. Reaction mechanism and physiological role in microorganisms |
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393 | (6) |
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Involvement of the pyrophosphate and nicotinamide binding regions of Anabaena PCC7119 ferredoxin-NADP+ reductase in coenzyme specificity |
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399 | (6) |
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Asp402 is the catalytic base in nitroalkane oxidase |
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405 | (6) |
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A new look at FMNH2-dependent monooxygenases |
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411 | (6) |
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Factors influencing the flavin conformation in phenol hydroxylase (PHHY) from Trichosporon cutaneum |
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417 | (6) |
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Positioning of Arg-268 in L-lactate oxidase from Aerococcus viridans |
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423 | (6) |
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Monomeric sarcosine oxidase: evidence for an ionizable group in the ES complex and role of histidine 269 in catalysis |
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429 | (6) |
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Rapid kinetic study of extracellular flavocytochrome cellobiose dehydrogenase from the white-rot fungus Phanerochaete chrysosporium |
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435 | (6) |
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Activated flavins and their calculated N(5) NMR shieldings |
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441 | (6) |
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Protective peroxide reduction via flavoprotein disulfide reductases and Trx or Grx homologues in alkyl hydroperoxide reductase systems: studies of an unusual peroxidase system from Clostridium pasteurianum |
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447 | (6) |
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Overexpression and purification of the hypothetical sarcosine dehydrogenase of pAO1 of Arthrobacter nicotinovorans: consequence of amino acid replacement on covalent FAD-binding |
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453 | (8) |
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III. Electron Transfer in Complex Flavoprotein Systems |
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Molecular enzymology of the diflavin reductases |
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461 | (10) |
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The Escherichia coli sulfite reductase flavoprotein component: a structural and functional study |
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471 | (10) |
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The divergent family of dihydroorotate dehydrogenases |
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481 | (10) |
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Structure and recognition of components of the mitochondrial steroid hydroxylating system in adrenal cortex of vertebrates |
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491 | (10) |
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The NO synthase flavoprotein: kinetic and structural studies to reveal its unique mechanism of regulation |
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501 | (8) |
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Protein film voltammetry in flavoprotein research |
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509 | (10) |
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Chimeric enzymes generated by domain swapping between two isoforms of ferredoxin-NADP+ reductase |
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519 | (6) |
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Calmodulin-dependent activation of neuronal NO synthase reductase domain: the role of NADPH |
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525 | (6) |
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Electron transfer in the hybrid system formed by ferredoxin-NADP+ reductase from Anabaena and bovine adrenodoxin |
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531 | (6) |
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A novel NADPH-ferredoxin reductase of Mycobacterium tuberculosis |
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537 | (6) |
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Assessing protein-protein interactions between the flavoprotein and ferredoxin component of the benzene dioxygenase system from Pseudomonas putida by kinetic analysis, chemical cross-linking and TOF-MS |
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543 | (8) |
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NMR relaxation study of the fast internal dynamics of flavodoxin from Cyanobacterium anabaena |
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551 | (6) |
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An investigation of the effects of pH on the 15N and 31P nmr spectra of FMN hydroquinone in flavodoxin from Desulfovibrio vulgaris |
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557 | (6) |
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Mechanistic studies on the intramolecular one-electron transfer between the two flavins in the human nNOS and iNOS flavin domains |
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563 | (6) |
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Relaxation kinetics of cytochrome P450 reductase |
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569 | (6) |
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Catalytic cycles and rate-limited steps of the Thr66-substituted porcine liver NADH-cytochrome b5 reductase catalytic domains |
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575 | (6) |
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Electron transfer in the reductase domain of neuronal nitric oxide synthase |
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581 | (6) |
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The flavin binding sub-domains of rat neuronal nitric oxide synthase |
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587 | (4) |
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Electron transfer to bacterial cytochromes P450 mediated by the Escherichia coli flavodoxin reductase and flavodoxin redox system |
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591 | (6) |
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A mutational analysis of the functionally important contacts between flavin and heme domains in flavocytochrome b2 |
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597 | (8) |
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Expression and thermodynamic characterization of the Mycobacterium tuberculosis adrenodoxin reductase homologue: FprA |
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605 | (6) |
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Role of the carboxyl-terminal tyrosine of ferredoxin-NADP+ reductase in the electron transfer processes with the protein carriers ferredoxin and flavodoxin |
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611 | (6) |
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Novel FAD derivatives in electron-transferring flavoprotein from Megasphaera elsdenii |
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617 | (6) |
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Role of residues Thr56, Asn58 and Asn97 from Anabaena flavodoxin in the electron transfer processes with ferredoxin-NADP+ reductase |
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623 | (6) |
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Effects of mutation at phenylalanine 393 on the catalytic cycle of flavocytochrome P450 BM3 |
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629 | (6) |
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Probing the reductive reaction of the FAD and CPR domains of flavocytochrome P450 BM3 |
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635 | (6) |
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Reduction of electron-transferring flavoprotein from Megasphaera elsdenii by NADH and D-lactate dehydrogenase |
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641 | (6) |
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The interaction of trimethylamine dehydrogenase with electron-transferring flavoprotein |
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647 | (6) |
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Electron transfer in the alkane hydroxylase system of Pseudomonas oleovorans |
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653 | (6) |
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Phosphate mediates electron transfer in pyruvate oxidase from Lactobacillus plantarum |
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659 | (4) |
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Acetohydroxyacid synthase catalyses electron transfer between α-hydroxy-ethyl-thiamin diphosphate and FAD in a slow side reaction of catalysis |
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663 | (4) |
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Spectroscopic properties of NqrF, the electron input subunit of the Na+-translocating NADH: quinone oxidoreductase: a FAD-Fe/S-protein |
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667 | (6) |
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Transient kinetic analysis of the reductive half reaction of methionine synthase reductase |
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673 | (6) |
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H-bonding features in two redox states between the isoalloxazine ring and the protein moieties of flavodoxin from Desulfovibrio vulgaris |
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679 | (6) |
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Evidence that the flavin redox state regulates conformational changes and membrane binding in PutA from Escherichia coli |
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685 | (6) |
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Intramolecular electron transfer pathway in mutants of AhpF, a flavoprotein disulfide reductase |
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691 | (8) |
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IV. Flavins Light and Biology |
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Dark and photoexcited crystal structures of a plant blue-light photoreceptor domain: a light-driven flavin-cysteinyl adduct |
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699 | (2) |
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Ultrafast spectroscopy of the excited flavin radical and its primary photoproduct in DNA photolyase from E. coli |
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701 | (6) |
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Photochemistry of a C450A mutant of the LOV2 domain in phototropin: detection of a light-induced neutral flavin radical by EPR spectroscopy |
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707 | (6) |
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A comparative time-resolved electron paramagnetic resonance study of the flavin cofactor photoreduction in Escherichia coli cyclobutane pyrimidine dimer photolase and Xenopus laevis (6-4) photolyase |
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713 | (6) |
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NMR studies on the mechanism of the blue light receptor phototropin from Avena sativa |
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719 | (6) |
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Effect of the position of the methyl group on spectroscopy and photophysics of iso-and alloxazines in solution |
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725 | (6) |
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