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This book constitutes the refereed proceedings of the First International Conference on Data Management in Grid and Peer-to-Peer Systems, Globe 2008, held in Turin, Italy, September2008. P2P and grid computing are important for scale distributed systems and applications that require effective management of voluminous, distributed, and heterogeneous data.The 10 revised full papers presented were carefully reviewed and selected from 23 submissions. The papers are organized in topical sections on P2P storage systems and caching, P2P data integration systems, querying in grid and P2P systems.