| Preface |
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| Color Plates |
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IX | |
| Part I. Introduction |
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1 | (6) |
| Part II. Analytical Methods for Metabolome Sciences |
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Chapter 2: Development and Application of Capillary Electrophoresis–Mass Spectrometry Methods to Metabolomics |
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7 | (18) |
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Chapter 3: Application of Electrospray Ionization Mass Spectrometry for Metabolomics |
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25 | (12) |
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Chapter 4: High-Performance Liquid Chromatography and Liquid Chromatography/Mass Spectrometry Analyses of Metabolites in Microorganisms |
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37 | (16) |
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Chapter 5: Metabolome Profiling of Human Urine with Capillary Gas Chromatography/Mass Spectrometry |
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53 | (22) |
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Chapter 6: Metabolic Profiling by Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR-MS) and Electrospray Ionization Quadrupole Time-Of-Flight Mass Spectrometry (ESI-Q-TOF-MS) |
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75 | (16) |
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Chapter 7: Metabolome Analysis by Capillary Electrophoresis |
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91 | (16) |
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Chapter 8: High-Performance Liquid Chromatography for Metabolomics: High-Efficiency Separations Utilizing Monolithic Silica Columns |
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T. Ikegami, H. Kobayashi, H. Kimura, V.V. Tolstikov, O. Fiehn, and N. Tanaka |
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107 | (20) |
| Part III. Applications of Metabolome Analysis to Biosciences |
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Chapter 9: Combined Analysis of Metabolome and Transcriptome: Catabolism in Bacillus subtilis |
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T. Nishioka, K. Matsuda, and Y. Fujita |
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127 | (14) |
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Chapter 10: Metabolomics in Arabidopsis thaliana |
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141 | (14) |
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Chapter 11: Lipidomics: Metabolic Analysis of Phospholipids |
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155 | (12) |
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Chapter 12: Chemical Diagnosis of Inborn Errors of Metabolism and Metabolome Analysis of Urine by Capillary Gas Chromatography/Mass Spectrometry |
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167 | (26) |
| Part IV. Metabolome Informatics |
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Chapter 13: Introduction to the ARM Database: Database on Chemical Transformations in Metabolism for Tracing Pathways |
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193 | (18) |
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Chapter 14: The Genome-Based E-CELL Modeling (GEM) System |
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K. Arakawa, Y. Yamada, K. Shinoda, Y. Nakayama, and M. Tomita |
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211 | (10) |
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Chapter 15: Hybrid Dynamic/Static Method for Large-Scale Simulation of Metabolism and its Implementation to the E-CELL System |
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221 | (12) |
| Part V. Metabolomics and Medical Sciences |
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Chapter 16: Metabolomics and Medical Sciences |
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233 | (12) |
| Index |
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245 | |