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Serving a broad community of researchers and practitioners conducting basic and clinical research on carotenoids and vitamin A for medical purposes, this book evaluates basic research, epidemiological studies, and clinical trials in the field. It updates information on the worldwide problem of vitamin A deficiency and discusses extensively the pros and cons of carotenoid supplementation in cancer. The authors provide a comprehensive overview of the efforts made in the field of carotenoid research with respect to translational medicine and present a future outlook on carotenoids as new therapeutic agents.