9780721678405

Endocrinology

by ;
  • ISBN13:

    9780721678405

  • ISBN10:

    0721678408

  • Edition: 4th
  • Format: Hardcover
  • Copyright: 2001-01-01
  • Publisher: Elsevier Science Health Science div

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Summary

The new edition of this comprehensive classic offers a vast account of endocrinology and metabolism. The chapters are written by acknowledged experts in their field. From the basic scientific foundations of endocrinology to the practicalmanagement of endocrine disorders, this resource is a must-have for every practising endocrinologist.

Table of Contents

PART I Principles of Hormone Action 1(166)
J. Larry Jameson
An Introduction to Endocrinology
1(2)
D. Lynn Loriaux
Hormones and Gene Expression: Basic Principles
3(12)
Christine Campion Quirk
John H. Nilson
Control of Hormone Secretion
15(10)
Thomas F. J. Martin
Receptor Tyrosine Kinases
25(24)
Joseph Avruch
Hormone Signaling via Cytokine Receptors and Receptor Serine Kinases
49(9)
Lawrece S. Mathews
Dana Gaddy-Kurten
Hormone Signaling via G Protein-Coupled Receptors
58(15)
Andrew Shenker
The Cyclic AMP Second Messenger Signaling Pathway
73(16)
Joel F. Habener
Second Messenger Signaling Pathways: Phospholipids and Calcium
89(10)
Marvin C. Gershengorn
Patricia M. Hinkle
Mitogen-Activated Protein Kinase and Growth Factor Signaling Pathways
99(24)
John M. Kyriakis
Nuclear Receptor Superfamily
123(20)
Etienne-Emile Baulieu
Jan Mester
Gezard Reduilh
Applications of Molecular Biology and Genetics in Endocrinology
143(24)
J. Larry Jameson
PART II Neuroendocrinology and Pituitary Gland 167(222)
Shlomo Melmed
Basic Physiology
167(1)
Functional Pituitary Anatomy and Histology
167(16)
Sylvia L. Asa
Eva Horvath
Kalman Thomas Kovacs
Neurotransmitters and Hypothalamic Control of Anterior Pituitary Function
183(18)
Yogesh C. Patel
Oxytocin
201(8)
Hans H. Zingg
Prolactin
209(12)
Nelson D. Horseman
Adrenocorticotropic Hormone
221(14)
Anne White
David W. Ray
Endocrine and Other Biologic Rhythms
235(22)
Eve Van Cauter
Georges Copinschi
Fred W. Turek
Clinical Disorders
257(1)
Radiographic Evaluation of the Pituitary and Anterior Hypothalamus
257(12)
Robert J. Witte
Leighton P. Mark
David L. Daniels
Victor M. Haughton
Hypothalamic Syndromes
269(13)
Glenn D. Braunstein
Evaluation of Pituitary Masses
282(7)
Shlomo Melmed
Hypopituitarism
289(11)
Catherine Ann Lissett
Stephen Michael Shalet
Acromegaly
300(13)
Shlomo Melmed
Gonadotroph Adenomas
313(8)
Peter J. Synder
TSH-Producing Adenomas
321(8)
Paolo Beck-Peccoz
Luca Persani
Prolactinomas and Hyperprolactinemic Syndrome
329(14)
Giovanni Faglia
Sugical Management of Pitutary Tumors
343(11)
Reza Jarrahy
Hrayr K. Shahinian
Sellar and Parasellar Tumors in Children
354(9)
Sandeep Kunwar
Charles B. Wilson
Vasopressin, Diabetes Insipidus, and Syndrome of Inappropriate Antidiuresis
363(14)
Peter H. Baylis
The Pineal Gland: Basic Physiology and Clinical Implications
377(12)
Josephine Arendt
PART III Growth and Maturation 389(167)
Shlomo Melmed
Basic Physiology
389(1)
Growth Hormone
389(16)
John J. Kopchick
Growth Hormone-Releasing Hormone and Growth Hormone Secretagogues: Basic Physiology and Clinical Implications
405(22)
Bruce D. Gaylinn
Ralf Nass
Andrew A. Toogood
Michael O. Thorner
Somatostatin
427(12)
Agnes Schonbrunn
Insulin-Like Growth Factor-1 and Its Binding Proteins
439(22)
David R. Clemmons
Peptide Growth Factors Other Than Insulin-Like Growth Factors or Cytokines
461(16)
Peter S. Rotwein
Clinical Disorders
477(1)
Somatic Growth and Maturation
477(26)
Robert L. Rosenfield
Leona Cuttler
Growth Hormone Deficiency in Children
503(17)
Ron G. Rosenfeld
Growth Hormone Deficiency in Adults
520(9)
Ken K. Y. Ho
Aging, Endocrinology, and the Elderly Patient
529(27)
Jesse Roth
Christian A. Koch
Kristina I. Rother
PART IV Immunology and Endocrinology 556(44)
Leslie J. DeGroot
Immunologic Mechanisms Causing Autoimmune Endocrine Disease
556(15)
Kevan C. Herold
Jeffrey A. Bluestone
Interactions of the Endocrine and Immune Systems
571(16)
George P. Chrousos
llia J. Elenkov
The Autoimmune Polyglandular Syndromes
587(13)
Qiao-Yi Chen
Anjli Kukreja
Noel K. Maclaren
PART V Obesity, Anorexia Nervosa, and Nutrition in Endocrinology 600(54)
John C. Marshall
Appetite Regulation
600(5)
Stephen L. Lin
John F. Wilber
Leptin
605(10)
Rexford S. Ahima
Jeffrey S. Flier
Obesity
615(16)
Jamie Dananberg
Jose F. Caro
Anorexia Nervosa and Other Eating Disorders
631(11)
Robert T. Rubbin
Walter H. Kaye
Starvation and Nutritional Therapy
642(12)
David Heber
PART VI Diabetes Mellitus, Carbohydrate Metabolism, and Lipid Disorders 654(315)
Arthur H. Rubenstein
Basic Physiology
654(1)
Anatomy, Developmental Biology, and Pathology of the Pancreatic Islets
654(13)
Brigitte Reusens
Joseph J. Hoet
Claude Remacle
Chemistry and Biosynthesis of the Islet Hormones: Insulin, Islet Amyloid Polypeptide (Amylin), Glucagon, Somatostain, and Pancreatic Polypeptide
667(30)
Donald F. Steiner
Graeme I. Bell
Arthur H. Rubenstein
Shu J. Chan
Secretion and Metabolism of Insulin, Proinsulin, and C Peptide
697(15)
Kenneth S. Polonsky
Niall M. O'Meara
The Molecular Basis of Insulin Action
712(16)
Morris F. White
Martin G. Myers, Jr.
Glucagon Secretion, α Cell Metabolism, and Glucagon Action
728(9)
Daniel J. Drucker
Regulation of Intermediary Metabolism During Fasting and Feeding
737(19)
Ralph A. DeFronzo
Eleuterio Ferrannini
Clinical Disorders
756(1)
Classification and Diagnosis of Diabetes Mellitus
756(7)
Sean F. Dinneen
Robert A. Rizza
Type 1 (Insulin-Dependent) Diabetes Mellitus: Etiology, Pathogenesis, and Natural History
763(13)
Ake Lernmark
Type 2 Diabetes Mellitus: Etiology, Pathogenesis, and Natural History
776(23)
Jerrold M. Olefsky
Yolanta T. Kruszynska
Syndromes of Insulin Resistance and Mutant Insulin
799(11)
Jeffrey S. Flier
Christos Mantzoros
Management of Type 2 Diabetes: A Systematic Approach to Meeting the Standards of Care
810(11)
Self-Management Education, Medical Nutrition Therapy, and Exercise
810(11)
Richard M. Bergenstal
David M. Kendall
Marion J. Franz
Arthur H. Rubenstein
Management of Type 2 Diabetes: A Systematic Approach to Meeting the Standards of Care
821(15)
Oral Agents, Insulin, and Management of Complications
821(15)
Richard M. Bergenstal
David M. Kendall
Marion J. Franz
Arthur H. Rubenstein
Pancreas and Islet Transplantation
836(7)
R. Paul Robertson
The Relationship of Diabetic Control to Complications
843(14)
Robert B. Tattersall
Diabetes Mellitus: Oculopathy
857(11)
Ronald Klein
Diabetes Mellitus: Neuropathy
868(10)
Andrew J.M. Boulton
Rayaz A. Malik
Nephropathy: A Major Diabetic Complication
878(25)
Eli A. Fridman
Management of the Diabetic Foot Complication
903(5)
Gary W. Gibbons
Acute Complications of Diabetes Mellitus: Ketoacidosis, Hyperosmolar Coma, and Lactic Acidosis
908(13)
Daniel W. Foster
J. Denis McGarry
Hypoglycemia
921(20)
John E. Gerich
Diabetes, Lipids, and Atherosclerosis
941(13)
Alan Chait
Steven Haffner
Syndrome X
954(5)
Gerald M. Reaven
Hyperglycemia Secondary to Nondiabetic Conditions and Therapies
959(10)
Harold E. Lebovitz
Samy I. McFarlane
Index i
PART VII Parathyroid Gland, Calciotropic Hormones, and Bone Metabolism 969(299)
John T. Potts, Jr.
Basic Physiology
969(1)
Parathyroid Hormone and Parathyroid Hormone-Related Peptide in the Regulation of Calcium Homeostasis and Bone Development
969(30)
Harald W. Juppner
Thomas J. Gardella
Edward M. Brown
Henry M. Kronenberg
John T. Potts, Jr.
Calcitonin
999(10)
T. John Martin
Jane M. Moseley
Patrick M. Sexton
Vitamin D: From Photosynthesis, Metabolism, and Action to Clinical Applications
1009(20)
Roger Bouillon
Regulation of Calcium and Phosphate Homeostasis
1029(24)
F. Richard Bringhurst
Bone Development and Remodeling
1053(9)
Gideon A. Rodan
Clinical Disorders
1062(1)
Genetic Disorders of Calcium Homeostasis Caused by Abnormal Regulation of Parathyroid Hormone Secretion or Responsiveness
1062(13)
Rajesh V. Thakker
Harald Juppner
Primary Hyperparathyroidism
1075(18)
Shonni J. Silveberg
John P. Bilezikian
Malignancy-Associated Hypercalcemia
1093(8)
Andrew F. Stewart
Arthur E. Broadus
Medical Management of Hypercalcemia
1101(10)
Joel S. Finkelstein
Surgical Management of Hyperparathyroidism
1111(10)
Hop N. Le
Jeffrey A. Norton
Familial Hypocalciuric Hypercalcemia and Other Disorders Due to Calcium-Sensing Receptor Mutations
1121(12)
Ruben Diaz
Edward M. Brown
Hypoparathyroidism and Pseudohypoparathyroidism
1133(21)
Michael A. Levine
Hereditary Defects in Vitamin D Metabolism and Action
1154(15)
Rene St-Arnaud
Francis H. Glorieux
Nephrolithiasis
1169(12)
Jill S. Lindberg
Stauart M. Sprague
Clinical Approach to Metabolic Bone Disease
1181(6)
Murray J. Favus
Bone Density and Imaging of Osteoporosis
1187(20)
Christopher F. Njeh
Michael Jergas
Harry K. Genant
The Renal Osteodystrophies
1207(16)
Isidro B. Salusky
William G. Goodman
Jack W. Coburn
Disorders of Calcification: Osteomalacia and Rickets
1223(21)
Steven R. Goldring
Stephen M. Krane
Louis V. Avioli
Osteoporosis
1244(15)
Pierre D. Delmas
Roland D. Chapurlat
Paget's Disease of Bone
1259(9)
Frederick R. Singer
PART VIII Thyroid Gland 1268(348)
Leslie J. DeGroot
Basic Physiology
1268(1)
Anatomy and Development
1268(11)
Roberto Di Lauro
Mario De Felice
Thyrotropin-Releasing Hormone and Thyroid-Stimulating Hormone
1279(11)
Maurice F. Scanlon
Biosynthesis and Secretion of Thyroid Hormones
1290(11)
John T. Dunn
Thyroid Regulatory Factors
1301(26)
Jacques E. Dumont
Gilbert Vassart
Thyroid Hormone Binding and Metabolism
Thyroid Hormone Binding
1314(6)
Jan R. Stockgt
Thyroid Hormone Metabolism
1320(7)
Donald L. St. Germain
Mechanisms of Thyroid Hormone Action
1327(18)
J. Larry Jameson
Thyroid-Stimulating Hormone and Regulation of the Thyroid Axis
1345(16)
Bruce D. Weintraub
Rasa Kazlauskaite
Mathis Grossmann
Mariusz W. Szkundlinski
Thyroid Function Tests
1361(38)
Neil J.L. Gittoes
Jayne A. Franklyn
David H. Sarne
Samuel Refetoff
Michael C. Sheppard
Thyroid Imaging
1399(10)
Ralph R. Cavalieri
Manfred Blum
Clinical Disorders
1409(1)
Autoimmune Thyroid Disease
1409(13)
Anthony P. Weetman
Graves' Disease
1422(28)
Luca Chiovato
Giuseppe Barbesino
Aldo Pinchera
Ophthalmopathy
1450(12)
Henry B. Burch
Colum A. Gorman
George B. Bartley
Autonomously Functioning Thyroid Nodules and Other Causes of Thyrotoxicosis
1462(9)
Georg Hennemann
Chronic (Hashimoto's) Thyroiditis
1471(10)
Nobuyuki Amino
Hisato Tada
Yoh Hidaka
Infectious, Subacute, and Sclerosing Thyroiditis
1481(10)
Robert Volpe
Hypothyroidism and Myxedema Coma
1491(16)
Wilmar M. Wiersinga
Nonthyroidal Illness Syndrome
1507(10)
Leslie J. DeGroot
Multinodular Goiter
1517(12)
Laszlo Hegedus
Hans Gerber
Iodine Deficiency Disorders
1529(12)
Geraldo Medeiros-Neto
Thyroid Neoplasia
1541(26)
Furio Pacini
Leslie J. DeGroot
Surgery of the Thyroid
1567(20)
Edwin L. Kaplan
Sonia L. Sugg
Thyroid-Stimulating Hormone Receptor Mutations
1587(7)
Gilbert Vassart
Genetic Defects in Thyroid Hormone Synthesis and Action: Defects in Thyroid Hormone Synthesis
1594(9)
Jan J.M. de Vijlder
Thomas Vulsma
Transport Protein Variants
1603(6)
Jan R. Stockigt
Resistance to Thyroid Hormone
1609(7)
V. Krishna Chatterjee
Paolo Beck-Peccoz
PART IX Adrenal Gland and Glucocorticoids 1616(161)
D. Lynn Loriaux
Basic Physiology
1616(1)
The Principles, Pathways, and Enzymes of Human Steroidogenesis
1616(16)
Richard J. Auchus
Walter L. Miller
Glucocorticoid Action: Physiology
1632(15)
Allan Munck
Aniko Naray-Fejes-Toth
Glucocorticoid Action: Biochemistry
1647(8)
Roger L. Miesfeld
Diagnostic Implications of Adrenal Physiology and Clinical Epidemiology for Evaluation of Glucocorticoid Excess and Deficiency
1655(16)
David C. Aron
Clinical Disorders
1671(1)
Glucocorticoid Therapy
1671(12)
Lloyd Axelrod
Adrenal Insufficiency
1683(8)
D. Lynn Loriaux
Walter J. McDonald
Cushing's Syndrome
1691(25)
Lynnette K. Nieman
Generalized Glucocorticoid Resistance
1716(5)
Diana M. Malchoff
Carl D. Malchoff
Defects of Adrenal Steroidogenesis
1721(19)
Michael P. Wajnrajch
Maria I. New
Adrenarche
1740(7)
Lawrence N. Parker
Adrenal Imaging
1747(20)
John L. Doppman
Adrenal Cancer
1767(5)
David E. Schteingart
Adrenal Surgery
1772(5)
Allan E. Siperstein
Eren Berber
Index i
PART X Endocrine Hypertension and Mineralocorticoids 1777(108)
D. Lynn Loriaux
Basic Physiology
1777(1)
Biochemistry of Mineralocorticoids
1777(6)
Peter J. Fuller
John W. Funder
Aldosterone Action
1783(8)
Richard M. Mortensen
Gordon H. Williams
Hormones of the Cardiovascular System
1791(19)
Miriam T. Rademaker
Eric A. Espiner
Hormonal Regulation of Electrolyte and Water Metabolism
1810(10)
Aaron L. Friedman
Yoram Shenker
Theodore L. Goodfriend
Clinical Disorders
1820(1)
Primary Mineralocorticoid Excess Syndromes
1820(25)
Christopher R. W. Edwards
Hypoaldosteronism and Mineralocorticoid Resistance
1845(6)
James C. Melby
Sami T. Azar
Orthostatic Hypotension
1851(11)
David H.P. Streeten
Pheochromocytoma and Related Tumors
1862(23)
Harry R. Keiser
PART XI Reproductive Endocrinology and Sexual Development 1885(158)
William D. Odell
Basic Physiology
1885(1)
Gonadotropin-Releasing Hormone (GnRH) and GnRH Receptors
1885(10)
Robert Peter Millar
Gonadotropins
1895(10)
William R. Moyle
Gonadal Peptides: Inhibins, Activins, Follistatin-Inhibiting Substance (Antimullerian Hormone)
1905(11)
Henry G. Burger
Regulation of Gondotropin Synthesis and Secretion
1916(10)
John C. Marshall
Genetic Basis of Sex Determination and Sex Differentiation
1926(21)
Charmian A. Quigley
Anatomy and Endocrinology of Fetal Sex Differentiation
1947(8)
Nathalie Josso
Endocrinology of Sexual Maturation
1955(10)
William D. Odell
Environmental Agents and the Reproductive System
1965(9)
Jonathan Lindzey
Kenneth S. Korach
Clinical Disorders
1974(1)
Diagnosis and Treatment of Disorders of Sexual Development
1974(37)
Maguleone G. Forest
Precocious Puberty
2011(11)
Erica A. Eugster
Ora Hisch Pescovitz
Dealayed Puberty
2022(11)
Erica A. Eugster
Ora Hirsch Pescovitz
Gender Identity and Sexual Behavior
2033(10)
Louis J. G. Gooren
PART XII Female Reproduction 2043(138)
John C. Marshall
Basic Physiology
2043(1)
Ovarian Hormone Synthesis
2043(10)
Jerome F. Strauss III
Aaron J.W. Hsueh
Estrogen and Progesterone Action
2053(8)
Nancy L. Weigel
Brian G. Rowan
Folliculogenesis, Ovulation, and Luteogenesis
2061(12)
Gregory F. Erickson
Hormonal Regulation of the Menstrual Cycle and Mechanisms of Ovulation
2073(13)
John C. Marshall
Clinical Disorders
2086(1)
Amenorrhea, Anovulation, and Dysfunctional Uterine Bleeding
2086(19)
David T. Baird
Endometriosis
2105(7)
Linda C. Giudice
Female Infertility: Evaluation and Treatment
2112(10)
Lisa A. Farah
Richard E. Blackwell
Hyperandrogenism, Hirsutism, and the Polycystic Ovary Syndrome
2122(16)
David A. Ehrmann
Randall B. Barnes
Robert L. Rosenfield
Ovulation Induction and Assisted Reproduction
2138(9)
Machelle M. Seibel
Premenstrual Syndrome
2147(6)
Nancy E. Reame
Menopause and Hormone Replacement
2153(10)
William D. Odell
Henry G. Burger
Contraception
2163(9)
Daniel R. Mishell, Jr.
Ovarian Tumors with Endocrine Manifestations
2172(9)
Gary L. Keeney
PART XIII Endocrinology of the Breast 2181(28)
John C. Marshall
Hormonal Control of Breast Development
2181(8)
Jose Russo
Richard J. Santen
Irma M. Russo
Benign Breast Disorders
2189(10)
Richard J. Santen
JoAnn Pinkerton
Breast Cancer and Hormonal Management
2199(10)
William J. Gradishar
V. Craig Jordan
PART XIV Male Reproduction 2209(170)
Henry G. Burger
Basic Physiology
2209(1)
Functional Morphology
2209(23)
David M. de Krester
Gail P. Risbridger
Jeffrey B. Kerr
Androgen Action and Pharmacologic Uses
2232(11)
David J. Handelsman
Clinical Disorders
2243(1)
Use and Abuse of Anabolic Steroids
2243(14)
Don H. Catlin
Physiology and Pathophysiology of Andreogenetic Alopecia
2257(12)
Valerie Anne Randall
Clinical Disorders of the Testis
2269(22)
Stephen J. Winters
Cryptorchidism and Hypospadias
2291(5)
John M. Hutson
Mutations That Alter Androgen Receptor Function
2296(12)
Michael J. McPhaul
Male Infertility
2308(21)
H. W. Gordon Baker
Erectile Dysfunction
2329(6)
Stanley G. Korenman
Gynecomastia
2335(9)
Richard J. Santen
Male Contraception
2344(7)
David J. Handelsman
Testicular Tumors with Endocrine Manifestations
2351(6)
Ewa Rajpert-De Meyts
Jorma Toppari
Niels E. Skakkebaek
Endocrinology of the Prostate and Benign Prostatic Hyperplasia
2357(11)
Simon W. Hayward
Annemarie A. Donjacour
Axel A. Thomson
Gerald R. Cunha
Prostate Cancer
2368(11)
Chung Lee
James M. Kozlowski
PART XV Endocrinology of Pregnancy 2379(124)
William D. Odell
Basic Physiology
2379(1)
Placental Hormones
2379(12)
Samuel Parry
Jerome F. Strauss III
Implantation and Placental Physiology in Early Human Pregnancy: The Role of the Maternal Decidua and the Trophoblast
2391(9)
Linda C. Giudice
Susan J. Fisher
Fetal and Neonatal Endocrinology
2400(13)
Delbert A. Fisher
Fuel Homeostasis in the Fetus and Neonate
2413(14)
William W. Hay, Jr.
Marianne S. Anderson
Endocrinology of Parturition
2427(6)
John R. G. Challis
Clinical Disorders
2433(1)
Diabetes Mellitus and Pregnancy
2433(13)
Boyd E. Metzger
Lisa P. Purdy
Richard L. Phelps
Diagnosis and Treatment of Thyroid Disease During Pregnancy
2446(18)
Susan J. Mandel
Gerard N. Burrow
Endocrinology of Mammary Development, Lactation, and Galactorrhea
2464(12)
David L. Kleinberg
Gestational Trophoblastic Neoplasms
2476(13)
Charles B. Hammond
John T. Soper
Hormonal Changes and Endocrine Testing in Pregnancy
2489(14)
Mark E. Molitch
PART XVI Endocrine Tumor Syndromes 2503(71)
J. Larry Jameson
Multiple Endocrine Neoplasia Type 1
2503(15)
Rajesh V. Thakker
Multiple Endocrine Neoplasia Type 2
2518(15)
Robert F. Gagel
Carcinoid Tumors
2533(14)
Aaron I. Vinik
Gastrointestinal Hormones and Tumor Syndromes
2547(12)
Shahrad Taheri
Mohammad A. Ghatei
Stephen R. Bloom
Ectopic Hormone Syndromes
2559(15)
Helen E. Turner
John A. H. Wass
PART XVII Endocrine Testing and Treatment 2574(1)
William D. Odell
Endocrine Testing
2574(27)
Delbert A. Fisher
Jerald C. Nelson
Drugs and Hormones Used in Endocrinology
2601
Lora Armstrong
Index i

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