Essentials of General, Organic, and Biochemistry

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  • Edition: 2nd
  • Format: Hardcover
  • Copyright: 2014-01-15
  • Publisher: W. H. Freeman

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An innovative text from a highly experienced instructor, Denise Guinns Essentials of General, Organic, and Biochemistry offers a truly integrated approach to the course, with organic and biochemistry thoughtfully woven into every chapter. With its numerous connections between chemical concepts and health care applications, cases from clinical practice, and problem-solving support, Essentials of GOB provides students everything they need to learn the fundamentals of chemistry in the context of their future careers.

Author Biography

Denise Guinn received her BA in chemistry from the University of California at San Diego and her Ph.D. in organic chemistry from the University of Texas at Austin. She was a National Institutes of Health postdoctoral fellow at Harvard University before joining Abbott Laboratories as a Research Scientist in the Pharmaceutical Products Discovery Research Group. In 1992, Dr. Guinn joined the department of chemistry at Regis University, in Denver, Colorado, as Clare Boothe Luce Professor, where she taught courses in general chemistry, organic chemistry, and the General, Organic, and Biochemistry course for nursing and allied health majors.  In 2008 she joined the College of New Rochelle, where she teaches organic chemistry, biochemistry, and the general, organic and biochemistry course.  Her area of research is synthetic organic chemistry; she has published in the Journal of Organic Chemistry, the Journal of the American Chemical Society, and the Journal of Medicinal Chemistry. She has two college aged sons, and lives in Nyack, New York, with her Golden retriever Buddy.

Table of Contents

1. Measuring Matter and Energy
1.1 Matter and Energy
1.2 Metric and English Units
1.3 Significant Figures in Measurements
1.4 Dimensional Analysis and Unit Conversion

2. Atomic Structure and Nuclear Radiation
2.1 Elements and the Structure of the Atom
2.2 The Periodic Table of Elements
2.3 Electrons
2.4 Ions
2.5 Radioisotopes and Nuclear Radiation

3. Compounds and Molecules
3.1 Ionic Compounds
3.2 Covalent Compounds
3.3 Shapes of Covalent Molecules
3.4 Polar Bonds and Polar Molecules
3.5 Intermolecular Forces of Attraction

4. Chemical Reactions and Chemical Quantities
4.1 The Mole: Counting and Weighing Matter
4.2 Writing and Balancing a Chemical Equation
4.3 Energy and Chemical Reactions
4.4 Reaction Kinetics
4.5 Chemical Equilibrium

5. Changes of State and the Gas Laws
5.1 Changes of State
5.2 The Gas Laws
5.3 Gas Mixtures and Partial Pressure

6. Hydrocarbons
6.1 Introduction to Hydrocarbons
6.2 Structure of Alkanes
6.3 Writing Alkane Structures
6.4 Unsaturated Hydrocarbons: Alkenes and Alkynes
6.5 Naming Hydrocarbons
6.6 Aromatic Hydrocarbons

7. Organic Chemistry and Biomolecules
7.1 Alcohols and Ethers
7.2 Amines
7.3 Carbonyl Containing Functional Groups
7.4 Stereoisomers
7.5 Phosphate Ester Functional Groups

8. Mixtures, Solution Concentrations, and Diffusion
8.1 Mixtures and Solutions
8.2 Solution Concentrations
8.3 Colloidal Dispersions and Suspensions
8.4 Diffusion of Solutes and Solvent through Membranes

9. Acids and Bases
9.1 Acids and Bases
9.2 pH
9.3 Buffers

10. The Reactions of Organic Functional Groups in Biochemistry
10.1 Oxidation-Reduction Reactions
10.2 Group Transfer Reactions: Esterification and Amidation Reactions
10.3 Hydrolysis Reactions
10.4 Addition-Elimination Reactions involving Water: Hydration and Dehydration

11. Carbohydrates: Structure and Function
11.1 An Overview of Carbohydrates and their Function
11.2 The Structure of the Common Monosaccharides
11.3 The Structure of Complex Carbohydrates
11.4 The Role of Oligosaccharides as Cell Markers

12. Lipids: Structure and Function
12.1 Fatty Acids: A Component of Many Lipids
12.2 Triglycerides: Energy Storage Lipids
12.3 Phospholipid and Glycolipid Membrane Lipids
12.4 Cholesterol, Steroids and Lipoproteins

13. Proteins: Structure and Function
13.1 Amino Acids
13.2 Peptides
13.3 Protein Architecture
13.4 Enzymes

14. Nucleotides and Nucleic Acids
14.1 The Chemical Structure of Nucleotide and Polynucleotides
14.2 DNA Structure and Replication
14.3 The Role of DNA and RNA in Protein Synthesis

15. Metabolism and Bioenergetics
15.1 Overview of Energy and Metabolism
15.2 Carbohydrate Catabolism
15.3 Fatty Acid Catabolism
15.4 The Citric Acid Cycle
15.5 Oxidative Phosphorylation

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