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An innovative text from a highly experienced instructor, Denise Guinns Essentials of General, Organic, and Biochemistry offers a truly integrated approach to the course, with organic and biochemistry thoughtfully woven into every chapter. With its numerous connections between chemical concepts and health care applications, cases from clinical practice, and problem-solving support, Essentials of GOB provides students everything they need to learn the fundamentals of chemistry in the context of their future careers.
Denise Guinn received her BA in chemistry from the University of California at San Diego and her Ph.D. in organic chemistry from the University of Texas at Austin. She was a National Institutes of Health postdoctoral fellow at Harvard University before joining Abbott Laboratories as a Research Scientist in the Pharmaceutical Products Discovery Research Group. In 1992, Dr. Guinn joined the department of chemistry at Regis University, in Denver, Colorado, as Clare Boothe Luce Professor, where she taught courses in general chemistry, organic chemistry, and the General, Organic, and Biochemistry course for nursing and allied health majors. In 2008 she joined the College of New Rochelle, where she teaches organic chemistry, biochemistry, and the general, organic and biochemistry course. Her area of research is synthetic organic chemistry; she has published in the Journal of Organic Chemistry, the Journal of the American Chemical Society, and the Journal of Medicinal Chemistry. She has two college aged sons, and lives in Nyack, New York, with her Golden retriever Buddy.
Table of Contents
1. Measuring Matter and Energy 1.1 Matter and Energy 1.2 Metric and English Units 1.3 Significant Figures in Measurements 1.4 Dimensional Analysis and Unit Conversion2. Atomic Structure and Nuclear Radiation 2.1 Elements and the Structure of the Atom 2.2 The Periodic Table of Elements 2.3 Electrons 2.4 Ions 2.5 Radioisotopes and Nuclear Radiation3. Compounds and Molecules 3.1 Ionic Compounds 3.2 Covalent Compounds 3.3 Shapes of Covalent Molecules 3.4 Polar Bonds and Polar Molecules 3.5 Intermolecular Forces of Attraction4. Chemical Reactions and Chemical Quantities 4.1 The Mole: Counting and Weighing Matter 4.2 Writing and Balancing a Chemical Equation 4.3 Energy and Chemical Reactions 4.4 Reaction Kinetics 4.5 Chemical Equilibrium5. Changes of State and the Gas Laws 5.1 Changes of State 5.2 The Gas Laws 5.3 Gas Mixtures and Partial Pressure6. Hydrocarbons 6.1 Introduction to Hydrocarbons 6.2 Structure of Alkanes 6.3 Writing Alkane Structures 6.4 Unsaturated Hydrocarbons: Alkenes and Alkynes 6.5 Naming Hydrocarbons 6.6 Aromatic Hydrocarbons7. Organic Chemistry and Biomolecules 7.1 Alcohols and Ethers 7.2 Amines 7.3 Carbonyl Containing Functional Groups 7.4 Stereoisomers 7.5 Phosphate Ester Functional Groups8. Mixtures, Solution Concentrations, and Diffusion 8.1 Mixtures and Solutions 8.2 Solution Concentrations 8.3 Colloidal Dispersions and Suspensions 8.4 Diffusion of Solutes and Solvent through Membranes9. Acids and Bases 9.1 Acids and Bases 9.2 pH 9.3 Buffers10. The Reactions of Organic Functional Groups in Biochemistry 10.1 Oxidation-Reduction Reactions 10.2 Group Transfer Reactions: Esterification and Amidation Reactions 10.3 Hydrolysis Reactions 10.4 Addition-Elimination Reactions involving Water: Hydration and Dehydration11. Carbohydrates: Structure and Function 11.1 An Overview of Carbohydrates and their Function 11.2 The Structure of the Common Monosaccharides 11.3 The Structure of Complex Carbohydrates 11.4 The Role of Oligosaccharides as Cell Markers12. Lipids: Structure and Function 12.1 Fatty Acids: A Component of Many Lipids 12.2 Triglycerides: Energy Storage Lipids 12.3 Phospholipid and Glycolipid Membrane Lipids 12.4 Cholesterol, Steroids and Lipoproteins13. Proteins: Structure and Function 13.1 Amino Acids 13.2 Peptides 13.3 Protein Architecture 13.4 Enzymes14. Nucleotides and Nucleic Acids 14.1 The Chemical Structure of Nucleotide and Polynucleotides 14.2 DNA Structure and Replication 14.3 The Role of DNA and RNA in Protein Synthesis15. Metabolism and Bioenergetics 15.1 Overview of Energy and Metabolism 15.2 Carbohydrate Catabolism 15.3 Fatty Acid Catabolism 15.4 The Citric Acid Cycle 15.5 Oxidative Phosphorylation