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Dr. David Sibley, PhD, is a faculty member at the Washington University School of Medicine, where he teaches graduate courses in microbiology and has served on the steering committee for the Molecular Microbiology program for the past 10 years. In addition to authoring over 150 publications,?Dr. Sibley is an associate editor for PLoS Pathogens, edits reviews for Cellular Microbiology, and serves on the board of reviewing editors for Science.
Dr. Barbara Howlett, PhD, is a Professor in the School of Botany at the University of Melbourne, specializing in fungal diseases of plants. She serves in an editorial capacity for PLoS Pathogens, Eukaryotic Cell, and the European Journal of Plant Pathology.
Dr. Joseph Heitman, MD, PhD is currently Chair of the Dept of Molecular Genetics and Microbiology at Duke University. Dr. Heitman has co-authored four other books on the topics of eukayrotic function and pathogenesis, and serves as an editor for numerous?publication includingEukaryotic Cell, Virulence, and the Journal of Molecular Medicine.
Preface | p. ix |
Acknowledgments | p. xi |
Contributors | p. xiii |
General Overviews | p. 1 |
Population Genetics and Parasite Diversity | p. 3 |
Evolution of Meiosis, Recombination, and Sexual Reproduction in Eukaryotic Microbes | p. 17 |
Phylogenomic Analysis | p. 44 |
Phylogenetics and Evolution of Virulence in the Kingdom Fungi | p. 70 |
Population Genetics and Evolutionary Approaches | p. 91 |
Malaria: Host Range, Diversity, and Speciation | p. 93 |
From Population Genomics to Elucidated Traits in Plasmodium Falciparum | p. 111 |
Selective Sweeps in Human Malaria Parasites | p. 124 |
Evolution of Drug Resistance in Fungi | p. 143 |
Discovery of Extant Sexual Cycles in Human Pathogenic Fungi and Their Roles in the Generation of Diversity and Virulence | p. 168 |
Worldwide Migrations, Host Shifts, and Reemergence of Phytophthora Infestans, the Plant Destroyer | p. 192 |
Experimental and Natural Evolution of the Cryptococcus Neoformans and Cryptococcus Gattii Species Complex | p. 208 |
Population Genetics, Diversity, and Spread of Virulence in Toxoplasma Gondii | p. 231 |
Forward and Reverse Genetic Systems for Defining Virulence | p. 247 |
Genetic Crosses in Plasmodium Falciparum: Analysis of Drug Resistance | p. 249 |
Genetic Mapping of Virulence in Rodent Malarias | p. 269 |
Genetic Mapping of Acute Virulence in Toxoplasma Gondii | p. 285 |
Virulence in African Trypanosomes: Genetic and Molecular Approaches | p. 307 |
The Evolution of Antigenic Variation in African Trypanosomes | p. 324 |
Antigenic Variation, Adherence, and Virulence in Malaria | p. 338 |
Invasion Ligand Diversity and Pathogenesis in Blood-Stage Malaria | p. 362 |
Comparative "Omics" Approaches to Defining Virulence | p. 385 |
Evolution of Virulence in Oomycete Plant Pathogens | p. 387 |
Evolution and Genomics of the Pathogenic Candida Species Complex | p. 404 |
Evolution of Entamoeba Histolytica Virulence | p. 422 |
Sex and Virulence in Basidiomycete Pathogens | p. 437 |
Emergence of the Chytrid Fungus Batrachochytrium Dendrobatidis and Global Amphibian Declines | p. 461 |
Impact of Horizontal Gene Transfer on Virulence of Fungal Pathogens of Plants | p. 473 |
Evolution of Plant Pathogenicity in Fusarium Species | p. 485 |
Genetic, Genomic, and Molecular Approaches to Define Virulence of Aspergillus Fumigatus | p. 501 |
Ctyptosporidium: Comparative Genomics and Pathogenesis | p. 518 |
Index | p. 545 |
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