(0) items

Extracellular Matrix Biology,9781936113385
This item qualifies for


Your order must be $59 or more, you must select US Postal Service Shipping as your shipping preference, and the "Group my items into as few shipments as possible" option when you place your order.

Bulk sales, PO's, Marketplace Items, eBooks, Apparel, and DVDs not included.

Extracellular Matrix Biology

by ;


Pub. Date:
Cold Spring Harbor Laboratory Press
List Price: $144.00

Rent Textbook


Buy New Textbook

Usually Ships in 3-5 Business Days

Used Textbook

We're Sorry
Sold Out


We're Sorry
Not Available

More New and Used
from Private Sellers
Starting at $100.39

Questions About This Book?

Why should I rent this book?
Renting is easy, fast, and cheap! Renting from can save you hundreds of dollars compared to the cost of new or used books each semester. At the end of the semester, simply ship the book back to us with a free UPS shipping label! No need to worry about selling it back.
How do rental returns work?
Returning books is as easy as possible. As your rental due date approaches, we will email you several courtesy reminders. When you are ready to return, you can print a free UPS shipping label from our website at any time. Then, just return the book to your UPS driver or any staffed UPS location. You can even use the same box we shipped it in!
What version or edition is this?
This is the edition with a publication date of 10/31/2011.
What is included with this book?
  • The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any CDs, lab manuals, study guides, etc.
  • The Rental copy of this book is not guaranteed to include any supplemental materials. You may receive a brand new copy, but typically, only the book itself.


In most tissues, cells are surrounded by an extracellular matrix (ECM) containing proteins such as collagen, laminin, and fibronectin. The ECM plays an important role in the regulation of cell function. ECM proteins bind to cell surface receptors such as integrins, activating signaling pathways that regulate cellular morphology, adhesion, cell migration, cell proliferation, and apoptosis. This book covers all aspects of ECM composition and function, as well as alterations in the ECM that occur during tumorigenesis and other disease states. The editors are both giants in the field (Dr. Hynes discovered fibronectin), who are highly respected through the cell, molecular, and cancer biology communities.

Table of Contents

Prefacep. vii
Overview of the Matrisome- An Inventory of Extracellular Matrix Constituents and Functionsp. 1
Basement Membranes: Cell Scaffoldings and Signaling Platformsp. 17
The Collagen Familyp. 45
Heparan Sulfate Proteoglycansp. 65
The Thrombospondinsp. 99
Tenascins and the Importance of Adhesion Modulationp. 129
Fibronectins, Their Fibrillogenesis, and In Vivo Functionsp. 149
Integrin Structure, Activation, and Interactionsp. 169
Cross Talk among TGF- Signaling Pathways, Integrins, and the Extracellular Matrixp. 183
Molecular Architecture and Function of Matrix Adhesionsp. 201
Genetic Analyses of Integrin Signalingp. 223
Integrins and Extracellular Matrix in Mechanotransductionp. 245
Integrins in Cell Migrationp. 259
Extracellular Matrix Degradation and Remodeling in Development and Diseasep. 275
Extracellular Matrix in Development: Insights from Mechanisms Conserved between Invertebrates and Vertebratesp. 299
Angiogenesisp. 313
Extracellular Matrix: Functions in the Nervous Systemp. 333
Cell-Extracellular Matrix Interactions in Normal and Diseased Skinp. 357
Extracellular Matrix Proteins in Hemostasis and Thrombosisp. 371
Indexp. 389
Table of Contents provided by Ingram. All Rights Reserved.

Please wait while the item is added to your cart...