Fundamental Immunology

by Paul, William E.

• ISBN13: 9781451117837
• ISBN10: 1451117833
• Edition: 7th
• Format: Hardcover
• Copyright: 2012-12-19
• Publisher: LWW

Summary

Fundamental Immunology Seventh Edition This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text and image bank! Look inside and discover… Fully revised and updated contentreflects the latest advances in the field. Current insightsenhance readers' understanding of immune system function Unique approachbridges the gap between basic immunology and the disease process. Extensive coverage of molecular biologyexplains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tablesdeliver essential information at a glance. PLUS… A convenient companion websitefeatures the fully searchable text and image bank! Pick up your copy today!

Table of Contents

Section I. Introduction to Immunology

 

1          The Immune System  

William E. Paul

 

2          History of Immunology

            Steven Greenberg      

 

Section II. Organization and Evolution of the Immune System

 

3          Lymphoid Tissues and Organs

            Eitan M. Akirav, Noelia Alonso-Gonzalez, Lucy A. Truman, and Nancy H. Ruddle          

 

4          Evolution of the Immune System

            Martin F. Flajnik        

 

Section III. Immunoglobulins and B Lymphocytes

 

5          Immunoglobulins: Structure and Function

            Harry W. Schroeder   

 

6          Immunoglobulins: Molecular Genetics

            Edward E. Max and Sebastian Fugmann                  

 

7          Antigen-Antibody Reactions

            Jay A. Berzofsky and Ira Berkower  

 

8          B Lymphocyte Development

            Richard R.  Hardy     

 

9          B Lymphocyte Receptors, Signaling Mechanisms, and Activation

Akanksha Chaturvedi, Angel Davey, Wanli Liu, Hae Won Sohn, and Susan K. Pierce      

 

10        B Lymphocyte Responses

Michael McHeyzer-Williams 

 

Section IV. T Lymphocytes

 

11        T Lymphocyte Receptors

            Mark M. Davis           

 

12        T Lymphocyte Signaling Mechanisms

            Takashi Saito  

 

13        T Lymphocyte Developmental Biology         

Ellen V. Rothenberg and Ameya Champhekar

 

14        Peripheral T Lymphocyte Responses and Function   

Marc K. Jenkins

 

Section V. The Intersection of Innate and Adaptive Immunity

 

15        The Innate Immune System   

Luke A. J. O’Neill

 

16        Dendritic Cells

            Michel C. Nussenzweig         

 

17        Natural Killer Cells    

Wayne M. Yokoyama

 

18        CD1d-restricted NKT Cells

Albert S. Bendelac

           

19        Macrophages and Phagocytosis         

Siamon Gordon

 

20        Granulocytes and Mast Cells

Patrizia Scapini, Nicola Tamassia, Carlo Pucillo, and Marco A. Cassatella  

 

21        The Major Histocompatibility Complex and its Proteins

            David H. Margulies   

 

22        Antigen Processing and Presentation

            Ted H. Hansen and Paul A. Roche    

 

Section VI. Induction, Regulation, and Effector Functions of the Immune Response

 

23        Immunogenicity and Antigen Structure

            Jay A. Berzofsky       

 

24        Fc Receptors and Their Role in Immune Regulation and Inflammation       

Jeffrey V. Ravetch and Falk Nimmerjahn

 

25        Type I Cytokines and Interferons

            Warren J. Leonard     

 

26        Interleukin-1 Family Cytokines

            Charles A. Dinarello and Mihai G. Netea      

 

27        TNF-related Cytokines in Immunity

            Carl F. Ware   

 

28        Chemokines

            Philip M. Murphy       

 

29        Helper T Cell Differentiation and Plasticity

            John J. O’Shea           

 

30        Programmed Cell Death

            Andrew L. Snow and Michael J. Lenardo    

 

31        Immunological Memory         

            Shane Crotty, Susan M. Kaech, and Stephen P. Schoenberger         

 

32        Immunological Tolerance

            Pamela S. Ohashi       

 

33        Regulatory/Suppressor T Cells

            Ethan M. Shevach      

 

34        Mucosal Immunity and Microbiome

            Yasmine Belkaid        

 

35        Neurophysiological Reflex Mechanisms in Immunology      

Chavan and Kevin J. Tracey

 

36        Complement   

B. Paul Morgan

 

37        Cell-mediated Cytotoxicity

            Judy Lieberman         

 

Section VII. Immunity to Infectious Agents

 

38        The Immune Response to Parasites

            Thomas A. Wynne, David L. Sacks, Alan Sher, and Eleanor M. Riley        

 

39        Immunity to Viruses  

Hildegund C.J. Ertl

 

40        Immunity to Intracellular Bacteria

Anca Dorhoi, Stephen T. Reece, and Stefan H. E. Kaufmann         

 

41        Immunity to Extracellular Bacteria    

Moon H. Nahm and Jannet Katz

 

42        Immunology of HIV Infection

            Bruce Walker 

 

43        Vaccines         

Ennio De Gregorio, Ugo D’Oro, Sylvie Bertholet, and Rino Rappuoli

 

Section VIII. Immunologic Mechanisms in Disease

 

44        Organ-Specific Autoimmunity

Ken T. Coppieters, Matthias G. von Herrath, and Dirk Homann      

 

45        Allergy

            Marsha Wills-Karp     

 

46        Transplantation Immunology

            Megan Sykes  

 

47        Cancer Immunology

            Hans Schreiber           

 

48        Inborn Errors of Immunity

            Jean-Laurent Casanova, Mary Ellen Conley, and Luigi D. Notarangelo