The Granulomatous Disorders

by Edited by D. Geraint James , A. Zumla

• ISBN13: 9780521592215
• ISBN10: 0521592216
• Format: Hardcover
• Copyright: 1999-11-13
• Publisher: Cambridge University Press

Summary

This authoritative account of the granulomatous disorders provides a comprehensive overview of this complex group of diseases. Collectively, these disorders can present a bewildering array of symptoms, affecting all the body systems. This volume takes full account of recent advances in our knowledge of the molecular biology and immunology of these disorders, and casts fresh light on their diagnosis and treatment. This timely publication is organised to include chapters focused on causative agents and those addressing affected body systems. Highly illustrated throughout, including numerous colour plates, it encompasses and integrates the very latest science, pathology and practical clinical advice. Compiled by international authorities with chapters which combine the expertise of both a pathologist and clinician, it is sure to become an essential source of reference for a very wide readership including infectious disease specialists, immunologists, pathologists, radiologists, ophthalmologists and general physicians.

Table of Contents

List of contributors	vii
Preface	xi
Part I: Biology of granulomas
Biology and immunology of the granuloma	3	(14)
C. Agostini
G. Semenzato
Classification of granulomatous disorders: a clinico-pathological synthesis	17	(11)
D. Geraint James
W. Jones Williams
Imaging of granulomatous disorders	28	(28)
J. Richenberg
J.B. Bomanji
Electron microscopy of granulomas	56	(12)
E.A. Sheffield
The road from granuloma to fibrosis	68	(11)
D.E. Elliott
The GLUS syndrome: granulomatous lesions of unknown significance	79	(11)
H. Brincker
N.T. Pedersen
Experimental skin granulomas	90	(13)
W.L. Epstein
K. Fukuyama
Part II: Infectious granulomas
Granulomatous infections: an overview	103	(19)
A. Zumla
D. Geraint James
Microbiological diagnosis of granulomatous infections	122	(10)
S.H. Gillespie
Tuberculosis	132	(29)
A. Zumla
G. Rook
P. Mwaba
S. Lucas
Human disease caused by Mycobacterium bovis and its attenuated derivative, bacillus Calmette-Guerin (BCG)	161	(12)
J.M. Grange
Leprosy	173	(16)
A. Zumla
A. Ustianowski
S. Lucas
L. Munthali
Non-tuberculous or atypical Mycobacteria	189	(16)
M.H. Wansbrough-Jones
D. Banerjee
Helminth-induced granulomatous disease	205	(7)
G.C. Cook
Leishmaniasis	212	(23)
R. Baker
P. Chiodini
P. Kaye
Fungal infections	235	(22)
D.W. Denning
G.E. Wilson
Toxoplasmosis	257	(19)
R. Holliman
J. Johnson
M. Burke
Sexually transmitted granulomatous diseases	276	(23)
R. Baker
B. Peters
M.H. Griffiths
Part III: Granulomas and disease
Sarcoidosis	299	(21)
D. Geraint James
W. Jones Williams
Idiopathic systemic granulomatous vasculitis	320	(16)
J.T. Lie
Berylliosis	336	(16)
C. Saltini
T.N. Markham
W. Jones Williams
Bone marrow granulomas	352	(9)
B.J. Bain
Granuloma and cancer	361	(15)
F.K. Rømer
Pulmonary angiitis and granulomatosis	376	(11)
R.A. DeRemee
R.C. Anton
P.T. Cagle
Granulomas in primary immunodeficiency	387	(14)
A.D.B. Webster
P. Amlot
Part IV: Granulomas and body systems
Cardiovascular disorders	401	(8)
A.S. Teirstein
J.T. Fallon
Respiratory granulomatoses	409	(9)
D. Geraint James
W. Jones Williams
Granulomatous liver disorders	418	(7)
Dame Sheila Sherlock
Granulomatous disorders of the nervous system	425	(20)
O.P. Sharma
V. Oksanen
Crohn's disease and other granulomatous diseases of the intestines	445	(23)
J.V. Weinstock
D.E. Elliott
Lymphoreticular system	468	(7)
D. Geraint James
W. Jones Williams
Granulomatous disorders of the female genital tract	475	(10)
L. Regan
E. Cela
Skin granulomas in clinical practice	485	(43)
S. Chopra
F. Vega-Lopez
Kidney disorders	528	(12)
H.J. Lachmann
M.H. Griffiths
B.I. Hoffbrand
Granulomatous disorders of the eye	540	(17)
A.A.S. Dunlop
P. Luthert
S. Lightman
Paediatric granulomas	557	(30)
R.J. Fitzgerald
P.E. Campbell
Index	587