9780126506419

Handbook of Forensic Drug Analysis

by ;
  • ISBN13:

    9780126506419

  • ISBN10:

    0126506418

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2004-12-13
  • Publisher: Elsevier Science
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Summary

The Handbook of Forensic Drug Analysis provides in-depth, up-to-date methods and results of forensic drug analyses. Chapters written by leading researchers in the field discuss the various forms of the drug as well as the origin and nature of samples. How to perform various tests, the use of best practices, and the analysis of results are discussed in detail. Numerous forensic and chemical analytic techniques are covered including immunoassay, gas chromatography, and mass spectrometry. This complete volume is the only compendium of it's kind on illicit drugs and analysis and should serve as a widely used reference for professionals. In addition, it can also be used as a standard textbook for graduate courses in forensic science.

Table of Contents

Foreword ix
Preface xi
About the Authors xvi
Overview of Forensic Drug Analysis
Drug Classifications
1(1)
Collection of Evidence in Drug Cases (Documentation, Safety, Packaging, Custody)
2(2)
Laboratory Capabilities and Accreditation
4(9)
Definition of Terms
9(3)
Reference
12(1)
Immunoassay Technologies for Drugs-of-Abuse Testing
Introduction
13(4)
Radioimmunoassay (RIA)
17(1)
Enzyme Immunoassay (EMIT, ELISA, CEDIA, and other EIAs)
18(6)
Fluorescence Polarization Immunoassay (FPIA)
24(2)
Kinetic Interaction of Microparticles in Solution (KIMS)
26(2)
Onsite (Point-of-Collection) Immunoassays
28(3)
Performance Characteristics and Quality Management of Immunoassays
31(3)
Summary
34(10)
References
34(10)
Cannabis: Methods of Forensic Analysis
Qualitative Seized-Drug Analysis of Cannabis, Hash, and Hash Oil: Current and Historical Perspectives
44(20)
Profiling---Provenance
64(16)
Immunoassays for the Detection of Cannabinoids in Biological Matrices
80(18)
Confirmation (Confirmatory Test) of Cannabinoids in Urine Specimens
98(56)
References
130(24)
Analysis of the Hallucinogens
PART I: INFRARED (IR) SPECTROSCOPY
154(22)
Theoretical Basis
154(2)
Infrared Spectrometer Instrumentation
156(8)
Infrared Spectroscopy of Lysergic Acid Diethylamide (LSD)
164(1)
Infrared Spectroscopy of Phenylalkylamines
165(3)
Infrared Spectroscopy of Phencyclidine and Analogs
168(2)
Infrared Spectroscopy of Tryptamines
170(2)
Further Reading
172(4)
PART II: MASS SPECTROMETRY
176(29)
Theoretical Basis
176(10)
Mass Spectroscopy of Lysergic Acid Diethlyamide (LSD)
186(1)
Mass Spectroscopy of Phenylalkylamines
187(2)
Mass Spectroscopy of Phencyclidine and Analogs
189(2)
Mass Spectroscopy of Tryptamines
191(4)
Further Reading
195(10)
Acknowledgment
202(1)
References
202(3)
PART III: NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
205(340)
Theoretical Basis
205(2)
The NMR Experiment
207(10)
Phencyclidine and Related Substances
217(3)
MDA and Analogs
220(7)
Ergot and Other Indole Alkaloids
227(2)
Tryptamines
229(6)
References
231(4)
Cocaine: Methods of Forensic Analysis
Introduction
235(1)
Origin of Cocaine Samples
236(1)
Noninstrumental Methods for Detection of Cocaine
237(10)
Trace and Instrumental Analysis
247(23)
Conclusions
270(7)
References
270(7)
Opioids: Methods of Forensic Analysis
Introduction
277(1)
Preliminary Methods for Opiate Detection
278(6)
Isolation of Opiates from Biosamples
284(6)
Papaver Somniferum as a Source of Opiates
290(6)
Heroin and Associated Illicit Opiate Formulations
296(25)
Other Opiate Agonists
321(19)
Summary
340(17)
Abbreviations
341(1)
References
342(15)
Amphetamines: Methods of Forensic Analysis
Introduction
357(4)
Detection
361(1)
Qualitative Methods of Analysis
362(12)
Quantitative Methods of Analysis
374(41)
Comparative Analysis and Profiling
415(17)
Conclusion
432(21)
References
433(20)
Illicit Drug Manufacture (With an Emphasis on Clandestine Methamphetamine Production): Synthetic Methods and Law Enforcement Concerns
Range of Operations in Clandestine Laboratories
453(25)
Manufacture of Methamphetamine
478(36)
Law Enforcement
514(18)
Concluding Remarks
532(13)
References
532(13)
Index 545

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