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Histology: A Text and Atlas With Correlated Cell and  Molecular Biology,9780781750561
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Histology: A Text and Atlas With Correlated Cell and Molecular Biology

by ;
Edition:
5th
ISBN13:

9780781750561

ISBN10:
0781750563
Format:
Paperback
Pub. Date:
12/5/2005
Publisher(s):
Lippincott Williams & Wilkins
List Price: $69.28
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Summary

Now it its Fifth Edition, this best-selling text and atlas is the perfect text for medical, health professions, and undergraduate biology students. It combines a detailed textbook that emphasizes clinical and functional correlates of histology with a beautifully illustrated atlas featuring full-color digital micrographs of the highest quality. This edition includes over 100 new illustrations, more Clinical Correlation boxes on the histology of common medical conditions, and new information on the molecular biology of endothelial cell function. Terminology throughout the text is consistent with Terminologia Anatomica. A powerful interactive histology atlas CD-ROM for students is included with the book and features all of the plates found in the text with interactive functionality.

Table of Contents

Methods
1(22)
Overview of Methods Used in Histology
1(1)
Tissue Preparation
2(1)
Histochemistry and Cytochemistry
3(9)
Microscopy
12(11)
Box 1.1. Clinical Correlation: Frozen Sections
4(3)
Box 1.2. Functional Considerations: Feulgen Microspectrophotometry
7(2)
Box 1.3. Clinical Correlation: Monoclonal Antibodies in Medicine
9(5)
Box 1.4. Proper Use of the Light Microscope
14(6)
Box 1.5. Functional Considerations: Development of Electron Microscopy
20(3)
The Cell Cytoplasm
23(48)
Overview of the Cell and Cytoplasm
23(2)
Membranous Organelles
25(30)
Nonmembranous Organelles
55(13)
Inclusions
68(1)
Cytoplasmic Matrix
69(2)
Box 2.1. Clinical Correlation: Lysosomal Storage Diseases
64
Box 2.2. Clinical Correlation: Abnormalities in Microtubules and Filaments
63(8)
The Cell Nucleus
71(21)
Overview of the Nucleus
71(1)
Nuclear Components
72(8)
Cell Renewal
80(1)
Cell Cycle
80(8)
Cell Death
88(4)
Box 3.1. Clinical Correlation: Cytogenetic Testing
76(7)
Box 3.2. Clinical Correlation: Regulation of Cell Cycle and Cancer Treatment
83(9)
Tissues: Concept and Classification
92(6)
Overview of Tissues
92(1)
Epithelium
92(1)
Connective Tissue
93(1)
Muscle Tissue
93(1)
Nerve Tissue
94(2)
Identifying Tissues
96(2)
Box 4.1. Clinical Correlation: Ovarian Teratomas
96(2)
Epithelial Tissue
98(48)
Overview of Epithelial Structure and Function
98(1)
Classification of Epithelium
99(1)
Cell Polarity
100(2)
The Apical Domain and Its Modifications
102(6)
The Lateral Domain and Its Specializations In Cell-To-Cell Adhesion
108(13)
The Basal Domain and Its Specializations In Cell-to-Extracellular Matrix Adhesion
121(11)
Glands
132(3)
Histogenesis of Epithelium
135(2)
Epithelial Cell Renewal
137(9)
Box 5.1. Clinical Correlation: Primary Ciliary Dyskinesia
107(5)
Box 5.2. Clinical Correlation: Junctional Complexes as a Target of Pathogenic Agents
112(11)
Box 5.3. Functional Considerations: Basement Membrane and Basal Lamina Terminology
123(15)
Box 5.4. Functional Considerations: Mucous and Serous Membranes
138(2)
Atlas Plates
Plate 1. Simple Squamous and Cuboidal Epithelia
140(2)
Plate 2. Simple and Stratified Epithelia
142(2)
Plate 3. Stratified Epithelia and Epithelioid Tissues
144(2)
Connective Tissue
146(36)
General Structure and Function of Connective Tissue
146(1)
Embryonic Connective Tissue
147(1)
Connective Tissue Proper
148(1)
Connective Tissue Fibers
149(12)
Extracellular Matrix
161(5)
Connective Tissue Cells
166(16)
Box 6.1. Clinical Correlation: Collagenopathies
158(3)
Box 6.2. Clinical Correlation: Fibrillin Microfilaments and Sun Exposure
161(9)
Box 6.3. Functional Considerations: The Mononuclear Phagocytotic System
170(6)
Atlas Plates
Plate 4. Loose and Dense Connective Tissue
176(2)
Plate 5. Dense Regular Connective Tissue, Tendons, and Ligaments
178(2)
Plate 6. Elastic Fibers and Elastic Lamellae
180(2)
Cartilage
182(20)
Overview of Cartilage
182(1)
Hyaline Cartilage
182(8)
Elastic Cartilage
190(1)
Fibrocartilage
190(1)
Chondrogenesis and Cartilage Growth
191(1)
Repair of Hyaline Cartilage
192(10)
Box 7.1. Clinical Correlation: Osteoarthritis
189(5)
Atlas Plates
Plate 7. Hyaline Cartilage
194(2)
Plate 8. Cartilage and the Developing Skeleton
196(2)
Plate 9. Elastic Cartilage
198(2)
Plate 10. Fibrocartilage
200(2)
Bone
202(36)
Overview of Bone
202(1)
Bones and Bone Tissue
203(2)
General Structure of Bones
205(3)
Cells of Bone Tissue
208(9)
Bone Formation
217(7)
Biologic Mineralization and Matrix Vesicles
224(1)
Physiologic Aspects of Bone
225(13)
Box 8.1. Clinical Correlation: Joint Diseases
205(12)
Box 8.2. Clinical Correlation: Nutritional Factors in Bone Formation
217(9)
Box 8.3. Functional Considerations: Hormonal Regulation of Bone Growth
226(2)
Atlas Plates
Plate 11. Bone, Ground Section
228(2)
Plate 12. Spongy and Compact Bone
230(2)
Plate 13. Endochondral Bone Formation I
232(2)
Plate 14. Endochondral Bone Formation II
234(2)
Plate 15. Intramembranous Bone Formation
236(2)
Adipose Tissue
238(9)
Overview of Adipose Tissue
238(1)
White Adipose Tissue
238(6)
Brown Adipose Tissue
244(3)
Box 9.1. Clinical Correlation: Obesity
243(2)
Box 9.2. Clinical Correlation: Adipose Tissue Tumors
245(2)
Blood
247(33)
Overview of Blood
247(1)
Plasma
248(2)
Erythrocytes
250(3)
Leukocytes
253(9)
Thrombocytes
262(2)
Formation of Blood Cells (Hemopoiesis)
264(9)
Bone Marrow
273(7)
Box 10.1. Clinical Correlation: ABO and Rh Blood Group Systems
252(2)
Box 10.2. Clinical Correlation: Hemoglobin Disorders
254(16)
Box 10.3. Clinical Correlation: Hemoglobin Breakdown and Jaundice
270(4)
Box 10.4. Clinical Correlation: Cellularity of the Bone Marrow
274(2)
Atlas Plates
Plate 16. Erythrocytes and Agranulocytes
276(2)
Plate 17. Granulocytes
278(2)
Muscle Tissue
280(38)
Overview and Classification of Muscle
280(1)
Skeletal Muscle
281(15)
Cardiac Muscle
296(4)
Smooth Muscle
300(18)
Box 11.1. Functional Considerations: Muscle Metabolism and Ischemia
285(5)
Box 11.2. Clinical Correlation: Muscular Dystrophy--Dystrophin and Dystrophin-Associated Proteins
290(1)
Box 11.3. Functional Considerations: The Sliding Filament Model
291(3)
Box 11.4. Clinical Correlation: Myasthenia Gravis
294(12)
Box 11.5. Functional Considerations: Comparison of the Three Muscle Types
306(2)
Atlas Plates
Plate 18. Skeletal Muscle
308(2)
Plate 19. Musculotendinous Junction and Neuromuscular Junction
310(2)
Plate 20. Cardiac Muscle
312(2)
Plate 21. Cardiac Muscle, Purkinje Fibers
314(2)
Plate 22. Smooth Muscle
316(2)
Nerve Tissue
318(46)
Overview of the Nervous System
319(1)
Composition of Nerve Tissue
319(1)
The Neuron
320(9)
Supporting Cells of the Nervous System
329(11)
Origin of Nerve Tissue Cells
340(1)
Organization of the Peripheral Nervous System
341(7)
Organization of the Central Nervous System
348(3)
Response of Neurons to Injury
351(13)
Box 12.1. Clinical Correlation: Parkinson's Disease
324(12)
Box 12.2. Clinical Correlation: Demyelinating Diseases
336(18)
Atlas Plates
Plate 23. Sympathetic and Dorsal Root Ganglia
354(2)
Plate 24. Peripheral Nerve
356(2)
Plate 25. Cerebrum
358(2)
Plate 26. Cerebellum
360(2)
Plate 27. Spinal Cord
362(2)
Cardiovascular System
364(32)
Overview of the Cardiovascular System
364(1)
Heart
365(5)
General Features of Arteries and Veins
370(2)
Arteries
372(7)
Capillaries
379(3)
Arteriovenous Shunts
382(1)
Veins
383(2)
Lymphatic Vessels
385(11)
Box 13.1. Clinical Correlation: Hypertension
372(7)
Box 13.2. Clinical Correlation: Atherosclerosis
379(7)
Box 13.3. Clinical Correlation: Ischemic Heart Disease
386(2)
Atlas Plates
Plate 28. Heart
388(2)
Plate 29. Aorta
390(2)
Plate 30. Muscular Arteries and Veins
392(2)
Plate 31. Arterioles and Lymphatic Vessels
394(2)
Lymphatic System
396(46)
Overview of the Lymphatic System
396(1)
Cells of the Lymphatic System
397(13)
Lymphatic Tissues and Organs
410(32)
Box 14.1. Functional Considerations: Origin of the Names T Lymphocyte and B Lymphocyte
401(1)
Box 14.2. Clinical Correlation: Hypersensitivity Reactions
402(6)
Box 14.3. Clinical Correlation: Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS)
408(22)
Atlas Plates
Plate 32. Tonsil
430(2)
Plate 33. Lymph Node I
432(2)
Plate 34. Lymph Node II
434(2)
Plate 35. Spleen I
436(2)
Plate 36. Spleen II
438(2)
Plate 37. Thymus
440(2)
Integumentary System
442(34)
Overview of the Integumentary System
442(1)
Layers of the Skin
443(3)
Cells of the Epidermis
446(6)
Structures of Skin
452(24)
Box 15.1. Functional Considerations: Skin Color
451(5)
Box 15.2. Functional Considerations: Hair Growth and Hair Characteristics
456(1)
Box 15.3. Functional Characteristics: The Role of Sebum
457(4)
Box 15.4. Clinical Correlation: Sweating and Disease
461(2)
Box 15.5. Clinical Correlation: Skin Repair
463(1)
Atlas Plates
Plate 38. Skin I
464(2)
Plate 39. Skin II
466(2)
Plate 40. Eccrine and Apocrine Sweat Glands
468(2)
Plate 41. Sweat and Sebaceous Glands
470(2)
Plate 42. Integument and Sensory Organs
472(2)
Plate 43. Hair Follicle and Nail
474(2)
Digestive System I: Oral Cavity and Associated Structures
476(42)
Overview of the Digestive System
476(1)
Oral Cavity
477(1)
Tongue
478(5)
Teeth and Supporting Tissues
483(12)
Salivary Glands
495(23)
Box 16.1. Clinical Correlation: The Genetic Basis of Taste
482(1)
Box 16.2. Clinical Correlation: Classification of Permanent (Secondary) and Deciduous (Primary) Dentition
483(13)
Box 16.3. Clinical Correlation: Dental Carles
496(8)
Box 16.4. Clinical Correlation: Salivary Glands Tumors
504(2)
Atlas Plates
Plate 44. Lip, a Mucocutaneous Junction
506(2)
Plate 45. Tongue I
508(2)
Plate 46. Tongue II
510(2)
Plate 47. Submandibular Gland
512(2)
Plate 48. Parotid Gland
514(2)
Plate 49. Sublingual Gland
516(2)
Digestive System II: Esophagus and Gastrointestinal Tract
518(58)
Overview of the Esophagus and Gastrointestinal Tract
519(3)
Esophagus
522(2)
Stomach
524(11)
Small Intestine
535(10)
Large Intestine
545(31)
Box 17.1. Clinical Correlation: Pernicious Anemia and Peptic Ulcer Disease
528(6)
Box 17.2. Functional Considerations: Enteroendocrine Cells, APUD Cells, and Gastrointestinal Hormones
534(1)
Box 17.3. Clinical Correlation: Zollinger-Ellison Syndrome
534(12)
Box 17.4. Functional Considerations: Digestive and Absorptive Functions of Enterocytes
546(7)
Box 17.5. Functional Considerations: Immune Functions of the Alimentary Canal
553(1)
Atlas Plates
Plate 50. Esophagus
554(2)
Plate 51. Esophagus and Stomach, Cardiac Region
556(2)
Plate 52. Stomach I
558(2)
Plate 53. Stomach II
560(2)
Plate 54. Gastroduodenal Junction
562(2)
Plate 55. Duodenum
564(2)
Plate 56. Jejunum
566(2)
Plate 57. Ileum
568(2)
Plate 58. Colon
570(2)
Plate 59. Appendix
572(2)
Plate 60. Anorectal Junction
574(2)
Digestive System III: Liver, Gallbladder, and Pancreas
576(36)
Liver
576(15)
Gallbladder
591(3)
Pancreas
594(18)
Box 18.1. Clinical Correlation: Congestive Heart Failure and Liver Necrosis
583(6)
Box 18.2. Clinical Correlation: Lipoproteins
589(13)
Box 18.3. Functional Considerations: Insulin Synthesis, an Example of Posttranslational Processing
602(2)
Atlas Plates
Plate 61. Liver I
604(2)
Plate 62. Liver II
606(2)
Plate 63. Gallbladder
608(2)
Plate 64. Pancreas
610(2)
Respiratory System
612(34)
Overview of the Respiratory System
612(1)
Nasal Cavities
613(4)
Pharynx
617(1)
Larynx
617(1)
Trachea
617(6)
Bronchi
623(1)
Bronchioles
623(2)
Alveoli
625(5)
Blood Supply
630(4)
Lymphatic Vessels
634(1)
Nerves
634(12)
Box 19.1. Clinical Correlation: Metaplasia
619(7)
Box 19.2. Clinical Correlation: Cystic Fibrosis
626(6)
Box 19.3. Clinical Correlation: Emphysema and Pneumonia
632(4)
Atlas Plates
Plate 65. Olfactory Mucosa
636(2)
Plate 66. Larynx
638(2)
Plate 67. Trachea
640(2)
Plate 68. Bronchiole and End Respiratory Passages
642(2)
Plate 69. Wall of Terminal Bronchiole, Respiratory Bronchiole, and Alveolus
644(2)
Urinary System
646(40)
Overview of the Urinary System
647(1)
General Structure of the Kidney
647(13)
Kidney Tubule Function
660(5)
Interstitial Cells
665(1)
Histophysiology of the Kidney
666(1)
Blood Supply
667(1)
Lymphatic Vessels
667(1)
Nerve Supply
668(1)
Ureter, Urinary Bladder, and Urethra
669(17)
Box 20.1. Functional Considerations: Vitamin D
647(11)
Box 20.2. Clinical Correlation: Urinalysis
658(1)
Box 20.3. Clinical Correlation: Renin--Angiotensin--Aldosterone System and Hypertension
659(3)
Box 20.4. Functional Considerations: Structure and Function of Aquaporin Water Channels
662(4)
Box 20.5. Functional Considerations: Hormonal Regulation of Collecting Duct Function
666(8)
Atlas Plates
Plate 70. Kidney I
674(2)
Plate 71. Kidney II
676(2)
Plate 72. Kidney III
678(2)
Plate 73. Kidney IV
680(2)
Plate 74. Ureter
682(2)
Plate 75. Urinary Bladder
684(2)
Endocrine Organs
686(42)
Overview of the Endocrine System
686(3)
Pituitary Gland (Hypophysis)
689(8)
Hypothalamus
697(1)
Pineal Gland
698(2)
Thyroid Gland
700(5)
Parathyroid Glands
705(1)
Adrenal Glands
706(22)
Box 21.1. Functional Considerations: Regulation of Pituitary Gland Secretion
695(2)
Box 21.2. Clinical Correlation: Diabetes Insipidus and ADH
697(6)
Box 21.3. Functional Considerations: Feedback Control of Thyroid Hormone Synthesis
703(1)
Box 21.4. Clinical Correlation: Abnormal Thyroid Function
704(6)
Box 21.5. Functional Considerations: Chromaffin Cells
710(3)
Box 21.6. Functional Considerations: Biosynthesis of Adrenal Hormones
713(3)
Atlas Plates
Plate 76. Pituitary I
716(2)
Plate 77. Pituitary II
718(2)
Plate 78. Pineal Gland
720(2)
Plate 79. Parathyroid and Thyroid Glands
722(2)
Plate 80. Adrenal Gland I
724(2)
Plate 81. Adrenal Gland II
726(2)
Male Reproductive System
728(44)
Overview of the Male Reproductive System
728(1)
Testis
729(5)
Spermatogenesis
734(8)
Seminiferous Tubules
742(4)
Intratesticular Ducts
746(1)
Excurrent Duct System
746(5)
Accessory Sex Glands
751(6)
Semen
757(1)
Penis
757(15)
Box 22.1. Functional Considerations: Hormonal Regulation of Spermatogenesis
736(6)
Box 22.2. Clinical Correlation: Factors Affecting Spermatogenesis
742(3)
Box 22.3. Clinical Correlation: Sperm-Specific Antigens and the Immune Response
745(10)
Box 22.4. Clinical Correlation: Benign Prostatic Hypertrophy and Cancer of the Prostate
755(3)
Box 22.5. Clinical Correlation: Mechanism of Erection and Erectile Dysfunction
758(2)
Atlas Plates
Plate 82. Testis I
760(2)
Plate 83. Testis II
762(2)
Plate 84. Ductuli Efferentes and Epididymis
764(2)
Plate 85. Spermatic Cord and Ductus Deferens
766(2)
Plate 86. Prostate Gland
768(2)
Plate 87. Seminal Vesicle
770(2)
Female Reproductive System
772(62)
Overview of the Female Reproductive System
773(1)
Ovary
773(15)
Uterine Tubes
788(2)
Uterus
790(6)
Placenta
796(5)
Vagina
801(2)
External Genitalia
803(1)
Mammary Glands
804(30)
Box 23.1. Clinical Correlation: Polycystic Ovarian Disease
781(4)
Box 23.2. Clinical Correlation: In Vitro Fertilization
785(2)
Box 23.3. Functional Considerations: Summary of Hormonal Regulation of the Ovarian Cycle
787(14)
Box 23.4. Clinical Correlation: Fate of Mature Placenta at Birth
801(2)
Box 23.5. Clinical Correlation: Cytologic Pap Smears
803(6)
Box 23.6. Functional Considerations: Lactation and Infertility
809(1)
Atlas Plates
Plate 88. Ovary I
810(2)
Plate 89. Ovary II
812(2)
Plate 90. Corpus Luteum
814(2)
Plate 91. Oviduct-Uterine Tube
816(2)
Plate 92. Uterus I
818(2)
Plate 93. Uterus II
820(2)
Plate 94. Cervix
822(2)
Plate 95. Placenta I
824(2)
Plate 96. Placenta II
826(2)
Plate 97. Vagina
828(2)
Plate 98. Mammary Gland
830(2)
Plate 99. Mammary Gland, Late Proliferative and Lactating
832(2)
Eye
834(32)
Overview of the Eye
834(1)
General Structure of the Eye
834(4)
Microscopic Structure of the Eye
838(28)
Box 24.1. Clinical Correlation: Glaucoma
845(2)
Box 24.2. Clinical Correlation: Retinal Detachment
847(5)
Box 24.3. Clinical Correlation: Age-Related Macular Degeneration (ARMD)
852(6)
Atlas Plates
Plate 100. Eye I
858(2)
Plate 101. Eye II: Retina
860(2)
Plate 102. Eye III: Anterior Segment
862(2)
Plate 103. Eye IV: Sclera, Cornea, and Lens
864(2)
Ear
866(22)
Overview of the Ear
866(1)
External Ear
866(1)
Middle Ear
867(3)
Internal Ear
870(18)
Box 25.1. Clinical Correlation: Vertigo
877(4)
Box 25.2. Clinical Correlation: Hearing Loss--Vestibular Dysfunction
881(3)
Atlas Plates
Plate 104. Ear
884(2)
Plate 105. Organ of Corti
886(2)
Index 888


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