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Human Genetics and Genomics, Includes Wiley E-Text,9780470654477
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Human Genetics and Genomics, Includes Wiley E-Text

by ;
Edition:
4th
ISBN13:

9780470654477

ISBN10:
0470654473
Format:
Paperback
Pub. Date:
2/11/2013
Publisher(s):
Wiley-Blackwell
List Price: $69.28

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Summary

This fourth edition of the best-selling textbook, Human Genetics and Genomics , clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today's genetics teaching, and includes updated discussion of genetic risk assessment, "single gene" disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice 'Hot topics' boxes that focus on the latest developments in testing, assessment and treatment 'Ethical issues' boxes to prompt further thought and discussion on the implications of genetic developments 'Sources of information' boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the enhanced Wiley Desktop Edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com , including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.

Author Biography

Bruce R. Korf is Wayne H. and Sara Crews Finley Chair in Medical Genetics, Professor and Chair, Department of Genetics, and Director, Heflin Center for Genomic Sciences, at the University of Alabama at Birmingham

Mira B. Irons
is Park Gerald Chair in Genetics and Associate Chief, Division of Genetics, at the Children’s Hospital Boston, and Associate Professor of Pediatrics at Harvard Medical School

Table of Contents

Preface

PART ONE: BASIC PRINCIPLES OF HUMAN GENETICS

1 DNA Structure and Function

2 Genetic Variation

3 Patterns of Inheritance

4 The Human Genome

5 Multifactorial Inheritance

6 Cell Division and Chromosomes

7 Population Genetics

8 Cancer Genetics

PART TWO: GENETICS AND GENOMICS IN MEDICAL PRACTICE

9 Chromosome Translocation

10 Molecular Diagnosis

11 Newborn Screening

12 Developmental Genetics

13 Carrier Screening

14 Genetic Risk Assessment

15 Genetic Testing for Risk of Cancer

16 Pharmacogenetics

17 Treatment of Genetic Disorders

Answers to Review Questions

Glossary

Index



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