The Human Microbiota How Microbial Communities Affect Health and Disease

by Fredricks, David N.

• ISBN13: 9780470479896
• ISBN10: 0470479892
• Edition: 1st
• Format: Hardcover
• Copyright: 2013-05-06
• Publisher: Wiley-Blackwell

Summary

The Human Microbiota offers a comprehensive review of all human-associated microbial niches in a single volume, focusing on what modern tools in molecular microbiology are revealing about human microbiota, and how specific microbial communities can be associated with either beneficial effects or diseases. An excellent resource for microbiologists, physicians, infectious disease specialists, and others in the field, the book describes the latest research findings and evaluates the most innovative research approaches and technologies. Perspectives from pioneers in human microbial ecology are provided throughout.

Author Biography

David Fredricks is an expert in infectious diseases and the human indigenous microbiota, with a research focus on the bacterial biota of the human vagina and how changes in the composition of vaginal microbes lead to the syndrome bacterial vaginosis. He has authored more than 32 peer reviewed journal articles, 7 book chapters, and 9 editorials or invited reviews. He has been a peer reviewer for more than a dozen major medical and infectious diseases journals, and has served on several NIH study sections.

Table of Contents

Preface David N. Fredricks, MD

Chapter 1. The NIH Human Microbiome Project
Lita M Proctor, PhD, Shaila Chhibba, Chris Wellington, Jean McEwen, JD, PhD, Jane Peterson, PhD, Maria Giovanni, PhD, Pamela McInnes, DDS MSc, and Carl Baker, MD, PhD, R. Dwayne Lunsford, PhD

Chapter 2. Methods for Characterizing Microbial Communities Associated with the Human Body
Vincent Young, MD PhD, Christine Bassis, PhD, and Thomas Schmidt, PhD

Chapter 3. Phyloarrays
Eoin L. Brodie, PhD, and Susan V. Lynch, PhD

Chapter 4. Mathematical Approaches for Describing Microbial Populations: Practice and Theory for Extrapolation of Rich Environments
Manuel E. Lladser, PhD, and Rob Knight, PhD

Chapter 5. Tension at the Border: How Host Genetics and the Enteric Microbiota Conspire to Promote Crohn’s Disease
Daniel N. Frank, PhD, and Ellen Li, MD, PhD

Chapter 6. The Human Airway Microbiome
Edith T. Zemanick, MD and J. Kirk Harris, PhD

Chapter 7. The Microbiota of the Mouth: Benefits and Malefits
Angela H. Nobbs, PhD, David Dymock, PhD, and Howard F. Jenkinson, PhD

Chapter 8. The Microbiota of the Genitourinary Tract
Laura Sycuro, PhD, MSc and David N. Fredricks, MD

Chapter 9. Functional Structure of Intestinal Microbiota in Health and Disease
Alexander Swidsinski, MD, PhD and Vera Loening-Baucke, MD

Chapter 10. From Fly to Man: Understanding How Commensal Microorganisms Influence Host Immunity and Health
June L. Round, PhD

Chapter 11. Insights into the Human Microbiome from Animal Models
Bethany A. Rader, PhD, and Karen Guillemin, PhD

Chapter 12. To Grow or Not to Grow: Isolation and Cultivation Procedures in the Genomic Age
Karsten Zengler, PhD

Chapter 13. New Approaches to Cultivation of Human Microbiota
Slava S. Epstein, PhD, Maria Sizova, PhD, and Amanda Hazen, MS

Chapter 14. Manipulating the Indigenous Microbiota in Humans: Prebiotics, Probiotics and Synbiotics
George T. Macfarlane, PhD, and Sandra Macfarlane PhD