Imaging in Parkinson's Disease

by Eidelberg, David

• ISBN13: 9780195393484
• ISBN10: 0195393481
• Format: Hardcover
• Copyright: 2011-08-30
• Publisher: Oxford University Press

Summary

Imaging in Parkinson's Diseaseprovides up-to-date information concerning new applications of brain imaging to the study of Parkinson's disease. Written by experts in the field, the book focuses on structural and functional imaging methodologies that have recently been applied to study the natural history of Parkinson's disease, with emphasis on the development of the major motor manifestations of the illness as well as cognitive impairment and dementia. Individual chapters address the role of imaging in differential diagnosis and in the evaluation of pharmacologic and surgical treatment effects. In-depth discussion of the use of imaging tools to study disease mechanisms is also provided, with emphasis on the roles of neuroinflammation, protein aggregation, and abnormal network organization in parkinsonism. Additionally, the text covers a number of relevant novel topics including recent advances in volumetric and functional MRI, echosonography, dopaminergic and cholinergic neurotransmitter imaging, and applications to experimental interventions such as gene therapy and transplantation. Covering a wide range of subjects and beautifully illustrated,Imaging in Parkinson's Diseaseis a valuable reference for neurologists, neurosurgeons and neuropsychologists, and a helpful resource for students engaged in postgraduate biomedical and clinical training.

Author Biography

David Eidelberg received his MD from Harvard Medical School in 1981. After completing residency training in neurology at Harvard, he pursued fellowship training in functional brain imaging research in London and New York. He is currently Head of the Center for Neurosciences at The Feinstein Institute for Medical Research. He is also director of the new NIH Morris K. Udall Center for Parkinson's Disease Research and Susan and Leonard Feinstein Professor of Neuroscience at The Feinstein Institute.

Dr. Eidelberg pioneered the use of functional imaging and network modeling to study the alterations in neural systems that occur in brain disease. He has been the recipient of many grants and awards, including the Fred Springer Award (2005) and the American Academy of Neurology Movement Disorders Research Award (2010).

Dr. Eidelberg currently serves on the scientific advisory board of The Michael J. Fox Foundation and is Scientific Director of The Thomas Hartman Foundation for Parkinson's Research. He also serves on the editorial boards of several major journals including Annals of Neurology and is Associate Editor of The Journal of Neuroscience.