9780123741790

International Review of Cytology: A Survey of Cell Biology

by
  • ISBN13:

    9780123741790

  • ISBN10:

    0123741793

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2007-08-01
  • Publisher: ACADEMIC PRESS INC

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Summary

International Review of Cytology presents current advances and comprehensive reviews in cell biology both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume include Mechanisms of Gradient Detection: A Comparison of Axon Pathfinding with Eukaryotic Cell Migration; Leptin and the Regulation of Hypothalamic-Pituitary-Adrenal Axis; Focal Adhesion and p53 Signaling in Cancer Cells; Cell and Molecular Biology of the Spindle Matrix; Mitochondrial Biology and Disease in Dictyostelium; Oxytocin and the Human Prostate in Health and Disease.

Table of Contents

Contributorsp. vii
Mechanisms of Gradient Detection: A Comparison of Axon Pathfinding with Eukaryotic Cell Migrationp. 1
Introductionp. 2
Mechanisms of Gradient Detection in Selected Eukaryotic Cell Typesp. 4
Common Grounds and Diversityp. 41
Concluding Remarksp. 51
Acknowledgmentsp. 52
Referencesp. 52
Leptin and the Regulation of the Hypothalamic-Pituitary-Adrenal Axisp. 63
Introductionp. 64
Biology of Leptin and Its Receptorsp. 65
Expression of Leptin and Its Receptors in the Hypothalamic-Pituitary-Adrenal Axisp. 69
Effects of Leptin on the Central Branch of the Hypothalamic-Pituitary-Adrenal Axisp. 76
Effects of Leptin on the Peripheral Branch of the Hypothalamic-Pituitary-Adrenal Axisp. 78
Involvement of Leptin in the Pathophysiology of the Hypothalamic-Pituitary-Adrenal Axisp. 85
Concluding Remarksp. 88
Acknowledgmentsp. 89
Referencesp. 89
Focal Adhesion Kinase and p53 Signaling in Cancer Cellsp. 103
Introductionp. 104
Structure and Function of Focal Adhesion Kinase Proteinp. 105
FAK in Tumorigenesisp. 122
FAK and p53 Associationp. 129
FAK and p53 Targeted Therapyp. 136
Summaryp. 138
Acknowledgmentsp. 138
Referencesp. 138
Cell and Molecular Biology of the Spindle Matrixp. 155
Introductionp. 156
Microtubule Spindle Dynamics and Force Productionp. 157
Evidence for a Spindle Matrixp. 161
Concluding Remarksp. 188
Acknowledgmentsp. 190
Referencesp. 190
Mitochondrial Biology and Disease in Dictyosteliump. 207
Introductionp. 208
Mitochondrial Biologyp. 209
Mitochondrial Diseasep. 223
Concluding Remarksp. 242
Referencesp. 243
Oxytocin and the Human Prostate in Health and Diseasep. 253
Introductionp. 254
The Human Prostatep. 254
Oxytocin and Oxytocin Receptorp. 259
Oxytocin and the Prostatep. 264
Possible Roles of Oxytocin in the Pathophysiology of Prostate Diseasep. 274
Concluding Remarksp. 278
Referencesp. 278
Indexp. 287
Table of Contents provided by Ingram. All Rights Reserved.

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