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In many cultures, Intra-Uterine Insemination(IUI) is often the treatment of choice for subfertile couples, as it is less invasive and less expensive than other treatments such as IVF or ICSI. Nevertheless, when applied wrongly or without adequate know-how and monitoring, it is potentially harmful and can often result in outcomes that have great additional costs and dangers associated, such as multiple pregnancy. Multiple pregnancy is a major cause of extra cost and danger in many markets such as the USA, and many of the lessons from IUI should be studied. This book presents a clear, comprehensive, and authoritative handbook on best practice globally.