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Introduction to Protein-DNA Interactions Structure, Thermodynamics, and Bioinformatics,9781936113491
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Introduction to Protein-DNA Interactions Structure, Thermodynamics, and Bioinformatics

by
ISBN13:

9781936113491

ISBN10:
193611349X
Format:
Hardcover
Pub. Date:
2/28/2013
Publisher(s):
Cold Spring Harbor Laboratory Press
List Price: $84.26

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This is the edition with a publication date of 2/28/2013.
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Summary

One of the foundations of molecular biology is how the interactions of proteins with DNA control many aspects of gene expression. Since the mid-20th century discoveries of the lac repressor and operator and the competition between the cI and cro proteins for the same segment of DNA, we have learned an enormous amount about the interactions of proteins with DNA and their control of fundamental processes in the cell. An Introduction to ProteinDNA Interactions: Structure, Thermodynamics, and Bioinformatics describes what we know about proteinDNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics and how each perspective informs the others. A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create unified view of the field and a fuller understanding of proteinDNA interactions.


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