The only textbook written for undergraduates by teachers of the course, this bestseller presents the most current concepts in an experimental context, conveying the excitement of scientific discovery, and highlighting important advances while providing unsurpassed pedagogical support for the first-time learner. The new edition is thoroughly updated, including most notably the new chapter on innate immunity.
Table of Contents
Part I Introduction 1. Overview of the Immune System 2. Cells and Organs of the Immune System 3. Innate Immunity
Part II Generation of B-Cell and T-Cell Receptors 4. Antibodies and Antigens 5. Organization and Expression of Immunoglobulin Genes 6. Antigen-Antibody Intereactions: Principles and Applications 7. The Complement System 8. The Major Histocompatibility Complex and Antigen Presentation 9. T-Cell Receptor 10. T-Cell Maturation, Activation, and Differentiation 11. B-Cell Generation, Activation and Differentiation
Part III Immune Effector Mechanisms 12. Cytokines 13. Leukocyte Activation and Migration 14. Cell-Mediated Cytotoxic Responses 15. Hypersensitivity Reactions
Part IV The Immune System in Health and Disease 16. Tolerance and Autoimmunity 17. Transplantation Immunology 18. Immune Responses to Infectious Diseases
19. Vaccines 20. AIDS and Other Immunodeficiencies 21. Cancer and the Immune System 22. Experimental Systems