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Laboratory animals, including ferrets, play an important role in biomedical research and advances. The humane care and management of these animals remains an ongoing concern. The ferret has emerged as the most popular animal model for studies on influenza. Published in full color to provide greater clarity to the techniques and concepts discussed, this guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the laboratory setting. It serves as a valuable, handy reference for both experienced individuals and for those without extensive training in working with the ferret.