Langman's Medical Embryology

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  • Edition: 11th
  • Format: Paperback
  • Copyright: 2009-01-30
  • Publisher: LWW
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Widely acclaimed for its scientific authority, pedagogy, clinical relevance, and clear, concise writing, this classic text covers all aspects of embryology of interest to medical, nursing, and health professions students. It features outstanding full-color illustrations and clinical images and photographs, end-of-chapter summaries and Problems to Solve, and Clinical Correlates boxes that provide information on birth defects and other clinical entities directly related to embryologic concepts. This Eleventh Edition has additional images in the birth defects chapters, many new full-color clinical photographs, and recolorized drawings. Other highlights include a glossary, new and updated Problems to Solve, and updated molecular genetics information. A companion Website will include the fully searchable text, interactive review questions and problems, updated Simbryo animations of embryologic system development, and PowerPoint slides for instructors.

Table of Contents

General Embryology
Embryology: Old and New Frontiers and an Introduction to Molecular Regulation and Signalingp. 3
Clinical Relevancep. 3
A Brief History of Embryologyp. 4
Introduction to Molecular Regulation and Signalingp. 5
Gametogenesis: Conversion of Germ Cells Into Male and Female Gametesp. 13
Primordial Germ Cellsp. 13
Clinical Correlatesp. 13
The Chromosome Theory of Inheritancep. 14
Clinical Correlatesp. 16
Morphological Changes During Maturation of the Gametesp. 24
Clinical Correlatesp. 30
First Week of Development: Ovulation to Implantationp. 33
Ovarian Cyclep. 33
Clinical Correlatesp. 33
Fertilizationp. 36
Clinical Correlatesp. 40
Cleavagep. 41
Blastocyst Formationp. 41
Uterus at Time of Implantationp. 43
Clinical Correlatesp. 43
Second Week of Development: Bilaminar Germ Discp. 47
Day 8p. 47
Day 9p. 47
Days 11 and 12p. 48
Day 13p. 50
Clinical Correlatesp. 51
Third Week of Development: Trilaminar Germ Discp. 55
Gastrulation: Formation of Embryonic Mesoderm and Endodermp. 55
Formation of the Notochordp. 55
Establishment of the Body Axesp. 56
Fate Map Established During Gastrulationp. 61
Growth of the Embryonic Discp. 61
Clinical Correlatesp. 61
Further Development of the Trophoblastp. 63
Third to Eighth Weeks: The Embryonic Periodp. 67
Derivatives of the Ectodermal Germ Layerp. 67
Clinical Correlatesp. 73
Derivatives of the Mesodermal Germ Layerp. 74
Clinical Correlatesp. 81
Derivatives of the Endodermal Germ Layerp. 82
Patterning of the Anteroposterior Axis: Regulation by Homeobox Genesp. 84
External Appearance During the Second Monthp. 85
Clinical Correlatesp. 87
Third Month to Birth: The Fetus and Placentap. 91
Development of the Fetusp. 91
Fetal Membranes and Placentap. 95
Clinical Correlatesp. 95
Clinical Correlatesp. 97
Structure of the Placentap. 100
Clinical Correlatesp. 102
Clinical Correlatesp. 103
Amnion and Umbilical Cordp. 104
Clinical Correlatesp. 105
Placental Changes at the End of Pregnancyp. 105
Clinical Correlatesp. 106
Amniotic Fluidp. 106
Fetal Membranes in Twinsp. 106
Clinical Correlatesp. 109
Parturition (Birth)p. 111
Clinical Correlatesp. 111
Birth Defects and Prenatal Diagnosisp. 113
Birth Defectsp. 113
Clinical Correlatesp. 120
Prenatal Diagnosisp. 121
Fetal Therapyp. 123
Systems-Based Embryology
Skeletal Systemp. 127
Skullp. 127
Clinical Correlatesp. 131
Limbsp. 134
Clinical Correlatesp. 140
Vertebrae and the Vertebral Columnp. 142
Ribs and Sternump. 144
Clinical Correlatesp. 144
Clinical Correlatesp. 145
Muscular Systemp. 147
Striated Skeletal Musculaturep. 147
Innervation of Axial Skeletal Musclep. 147
Molecular Regulation of Muscle Developmentp. 149
Patterning of Musclesp. 150
Head Musculaturep. 150
Limb Musculaturep. 150
Cardiac Musclep. 151
Smooth Musclep. 151
Clinical Correlatesp. 152
Body Cavitiesp. 155
Formation of the Intraembryonic Cavityp. 155
Serous Membranesp. 155
Clinical Correlatesp. 156
Diaphragm and Thoracic Cavityp. 159
Formation of the Diaphragmp. 159
Clinical Correlatesp. 162
Cardiovascular Systemp. 165
Establishment of the Cardiogenic Fieldp. 165
Formation and Position of the Heart Tubep. 165
Formation of the Cardiac Loopp. 168
Clinical Correlatesp. 170
Molecular Regulation of Cardiac Developmentp. 170
Development of the Sinus Venosusp. 171
Formation of the Cardiac Septap. 173
Clinical Correlatesp. 173
Clinical Correlatesp. 177
Clinical Correlatesp. 183
Formation of the Conducting System of the Heartp. 185
Vascular Developmentp. 185
Clinical Correlatesp. 190
Clinical Correlatesp. 195
Circulation Before and After Birthp. 196
Respiratory Systemp. 201
Formation of the Lung Budsp. 201
Clinical Correlatesp. 202
Larynxp. 203
Trachea, Bronchi, and Lungsp. 203
Maturation of the Lungsp. 205
Clinical Correlatesp. 206
Digestive Systemp. 209
Divisions of the Gut Tubep. 209
Molecular Regulation of Gut Tube Developmentp. 210
Mesenteriesp. 211
Foregutp. 212
Clinical Correlatesp. 213
Clinical Correlatesp. 218
Molecular Regulation of Liver Inductionp. 221
Clinical Correlatesp. 221
Pancreasp. 222
Clinical Correlatesp. 223
Midgutp. 223
Clinical Correlatesp. 227
Hindgutp. 230
Clinical Correlatesp. 231
Urogenital Systemp. 235
Urinary Systemp. 235
Clinical Correlatesp. 240
Clinical Correlatesp. 242
Clinical Correlatesp. 245
Genital Systemp. 246
Clinical Correlatesp. 254
Clinical Correlatesp. 257
Clinical Correlatesp. 258
Clinical Correlatesp. 262
Head and Neckp. 265
Pharyngeal Archesp. 267
Pharyngeal Pouchesp. 271
Pharyngeal Cleftsp. 273
Molecular Regulation of Facial Developmentp. 273
Clinical Correlatesp. 275
Tonguep. 277
Clinical Correlatesp. 278
Thyroid Glandp. 278
Clinical Correlatesp. 279
Facep. 280
Intermaxillary Segmentp. 282
Secondary Palatep. 283
Clinical Correlatesp. 284
Nasal Cavitiesp. 287
Teethp. 287
Molecular Regulation of Tooth Developmentp. 290
Clinical Correlatesp. 290
Central Nervous Systemp. 293
Spinal Cordp. 294
Clinical Correlatesp. 302
Brainp. 303
Clinical Correlatesp. 310
Molecular Regulation of Brain Developmentp. 313
Clinical Correlatesp. 315
Cranial Nervesp. 319
Autonomic Nervous Systemp. 319
Clinical Correlatesp. 323
Earp. 327
Internal Earp. 327
Middle Earp. 330
External Earp. 332
Clinical Correlatesp. 333
Eyep. 335
Optic Cup and Lens Vesiclep. 335
Retina, Iris, and Ciliary Bodyp. 337
Lensp. 339
Choroid, Sclera, and Corneap. 339
Vitreous Bodyp. 339
Optic Nervep. 340
Molecular Regulation of Eye Developmentp. 340
Clinical Correlatesp. 342
Integumentary Systemp. 345
Skinp. 345
Clinical Correlatesp. 346
Clinical Correlatesp. 346
Hairp. 347
Clinical Correlatesp. 348
Sweat Glandsp. 348
Mammary Glandsp. 348
Clinical Correlatesp. 349
Answers to Problemsp. 353
Glossary of Key Termsp. 362
Figure Creditsp. 369
Indexp. 373
Table of Contents provided by Ingram. All Rights Reserved.

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