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Lecture Notes: Clinical Biochemistry

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This is the 9th edition with a publication date of 10/14/2013.
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Concise yet comprehensive, Clinical Biochemistry Lecture Notes contains all the essential information for students and foundation doctors to understand the biochemical basis of disease and principles of biochemical diagnostics. It presents scientific principles in a clinical setting, with a range of case studies integrated into the text to clearly demonstrate how knowledge should be applied to real-life situations.

Key features include:
• The fundamental science underpinning common biochemical disorders and their investigation in clinical practice
• Accessible flow charts of biochemical processes and the reasoning behind specific tests, making look-up and understanding easy
• A brand new companion website at with self-assessment and downloadable summary slides for revision

Clinical Biochemistry Lecture Notes is an ideal overview and revision guide for medical students, foundation doctors, general practitioners, and nurses. It also provides a core text for scientific and medical staff pursuing a career in clinical biochemistry.

Table of Contents


List of abbreviations

1 Requesting and interpreting tests

2 Disturbances of water, sodium and potassium balance

3 Acid–base balance and oxygen transport

4 Renal disease

5 Disorders of calcium, phosphate and magnesium metabolism

6 Diabetes mellitus and hypoglycaemia

7 Disorders of the hypothalamus and pituitary

8 Abnormalities of thyroid function

9 Disorders of the adrenal cortex and medulla

10 Investigation of gonadal function, infertility, menstrual irregularities and hirsutism

11 Pregnancy and antenatal screening

12 Cardiovascular disorders

13 Liver disease

14 Gastrointestinal tract disease

15 Nutrition

16 Trauma, inflammation, immunity and malignancy

17 Disorders of iron and porphyrin metabolism

18 Uric acid, gout and purine metabolism

19 Central nervous system and cerebrospinal fluid

20 Therapeutic drug monitoring and chemical toxicology

21 Clinical biochemistry in paediatrics and the elderly


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