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The Machinery of Life
by Goodsell, David S.Edition:
2nd
ISBN13:
9780387849249
ISBN10:
0387849246
Format:
Hardcover
Pub. Date:
4/21/2009
Publisher(s):
Springer Verlag
List Price: $25.00
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Questions About This Book?
What version or edition is this?
This is the 2nd edition with a publication date of 4/21/2009.
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Summary
The Machinery of Life is a journey into the sub-microscopic world of molecular machines. Readers are introduced to the types of molecules built by cells, including proteins, nucleic acids, lipids, and polysaccharides; then, in a series of full-color "watercolor" illustrations, which show a portion of a living cell magnified by 1,000,000 times, the reader is guided through the interior world of cells. The book explores the ways in which molecules work in concert to perform the processes of living, and how vitamins, viruses, poisons, and drugs each have their effects on the molecules in our bodies. The book is a fascinating introduction to biochemistry for the non-specialist, and combines a lucid text with an abundance of drawings and computer graphics that present the world of cells and their components in a truly unique way.This new edition has been updated to include the many major advances of the past decade, and is richly illustrated in full color throughout.About the Author/Illustrator:Dr. David S. Goodsell is Associate Professor in the Department of Molecular Biology at The Scripps Research Institute, La Jolla, CA, USA. His illustrations have become well known and now appear in many publications as the primary demonstration of the crowded nature of cells. He has also provided expertise and illustrations to many science museums, most recently acting as a "thinking partner' for a new multi-site nanotechnology initiative headed in part by the Exploratorium in San Francisco.
Table of Contents
| Preface | p. vii |
| Introduction | p. 1 |
| A Matter of Scale | p. 3 |
| The Molecular World | p. 4 |
| Molecular Machines | p. 9 |
| Nucleic Acids | p. 13 |
| Proteins | p. 17 |
| Lipids | p. 19 |
| Polysaccharides | p. 23 |
| The Strange World of Molecules in Cells | p. 25 |
| The Processes of Living | p. 29 |
| Building Molecules | p. 30 |
| Harnessing Energy | p. 40 |
| Protection and Perception | p. 45 |
| Molecules in Cells: Escherichia coli | p. 53 |
| The Protective Barrier | p. 54 |
| Building New Proteins | p. 59 |
| Powering the Cell | p. 63 |
| Cellular Propellers | p. 65 |
| Molecular Warfare | p. 67 |
| A Human Cell: The Advantages of Compartments | p. 71 |
| The Human Body: The Advantages of Specialization | p. 83 |
| Infrastructure and Communication | p. 84 |
| Muscle | p. 87 |
| Blood | p. 92 |
| Nerves | p. 101 |
| Life and Death | p. 109 |
| Ubiquitin and the Proteasome | p. 110 |
| DNA Repair | p. 112 |
| Telomeres | p. 114 |
| Programmed Cell Death | p. 116 |
| Cancer | p. 118 |
| Aging | p. 120 |
| Death | p. 124 |
| Viruses | p. 127 |
| Poliovirus and Rhinovirus | p. 129 |
| Influenza Virus | p. 132 |
| Human Immunodeficiency Virus | p. 133 |
| Vaccines | p. 135 |
| You and Your Molecules | p. 141 |
| Vitamins | p. 142 |
| Broad-Spectrum Poisons | p. 146 |
| Bacterial Toxins | p. 148 |
| Antibiotic Drugs | p. 150 |
| Drugs and Poisons of the Nervous System | p. 154 |
| You and Your Molecules | p. 156 |
| Atomic Coordinates | p. 157 |
| Additional Reading | p. 159 |
| Index | p. 161 |
| Table of Contents provided by Ingram. All Rights Reserved. |
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