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The Machinery of Life



Pub. Date:
Springer Verlag
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This is the 2nd edition with a publication date of 4/21/2009.
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The Machinery of Life is a journey into the sub-microscopic world of molecular machines. Readers are introduced to the types of molecules built by cells, including proteins, nucleic acids, lipids, and polysaccharides; then, in a series of full-color "watercolor" illustrations, which show a portion of a living cell magnified by 1,000,000 times, the reader is guided through the interior world of cells. The book explores the ways in which molecules work in concert to perform the processes of living, and how vitamins, viruses, poisons, and drugs each have their effects on the molecules in our bodies. The book is a fascinating introduction to biochemistry for the non-specialist, and combines a lucid text with an abundance of drawings and computer graphics that present the world of cells and their components in a truly unique way.This new edition has been updated to include the many major advances of the past decade, and is richly illustrated in full color throughout.About the Author/Illustrator:Dr. David S. Goodsell is Associate Professor in the Department of Molecular Biology at The Scripps Research Institute, La Jolla, CA, USA. His illustrations have become well known and now appear in many publications as the primary demonstration of the crowded nature of cells. He has also provided expertise and illustrations to many science museums, most recently acting as a "thinking partner' for a new multi-site nanotechnology initiative headed in part by the Exploratorium in San Francisco.

Table of Contents

Prefacep. vii
Introductionp. 1
A Matter of Scalep. 3
The Molecular Worldp. 4
Molecular Machinesp. 9
Nucleic Acidsp. 13
Proteinsp. 17
Lipidsp. 19
Polysaccharidesp. 23
The Strange World of Molecules in Cellsp. 25
The Processes of Livingp. 29
Building Moleculesp. 30
Harnessing Energyp. 40
Protection and Perceptionp. 45
Molecules in Cells: Escherichia colip. 53
The Protective Barrierp. 54
Building New Proteinsp. 59
Powering the Cellp. 63
Cellular Propellersp. 65
Molecular Warfarep. 67
A Human Cell: The Advantages of Compartmentsp. 71
The Human Body: The Advantages of Specializationp. 83
Infrastructure and Communicationp. 84
Musclep. 87
Bloodp. 92
Nervesp. 101
Life and Deathp. 109
Ubiquitin and the Proteasomep. 110
DNA Repairp. 112
Telomeresp. 114
Programmed Cell Deathp. 116
Cancerp. 118
Agingp. 120
Deathp. 124
Virusesp. 127
Poliovirus and Rhinovirusp. 129
Influenza Virusp. 132
Human Immunodeficiency Virusp. 133
Vaccinesp. 135
You and Your Moleculesp. 141
Vitaminsp. 142
Broad-Spectrum Poisonsp. 146
Bacterial Toxinsp. 148
Antibiotic Drugsp. 150
Drugs and Poisons of the Nervous Systemp. 154
You and Your Moleculesp. 156
Atomic Coordinatesp. 157
Additional Readingp. 159
Indexp. 161
Table of Contents provided by Ingram. All Rights Reserved.

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