Martin's Physical Pharmacy and Pharmaceutical Sciences

by Sinko, Patrick J.

• ISBN13: 9780781750271
• ISBN10: 078175027X
• Edition: 5th
• Format: Hardcover
• Copyright: 2005-11-17
• Publisher: LWW

Summary

This text is the most comprehensive resource on the application of physical chemical principles in the various branches of pharmacy. It helps students, teachers, researchers, and manufacturing pharmacists use the elements of mathematics, chemistry, and physics in their work and study. This edition thoroughly examines basic physical pharmacy principles, equilibria phenomena, kinetic phenomena, dispersed systems, and drug delivery, and relates the pharmaceutical sciences to biological phenomena. New chapters cover biopharmaceutics and bioavailability; molecular and cellular biopharmaceutics; transporters and metabolizing enzymes; molding and compaction; and drug delivery systems. Significantly updated and revised review questions for each chapter are available in the book and on connection.LWW.com.

Table of Contents

Introduction	1	(20)
Basic Principles
States of Matter	21	(38)
Thermodynamics	59	(24)
Determination of the Physical Properties of Molecules	83	(36)
Equilibrium Phenomena
Nonelectrolytes	119	(24)
Solutions of Electrolytes	143	(18)
Ionic Equilibria	161	(26)
Electromotive Force and Oxidation--Reduction	187	(22)
Buffered and Isotonic Solutions	209	(22)
Solubility and Distribution Phenomena	231	(36)
Complexation and Protein Binding	267	(34)
Kinetic Phenomena
Diffusion	301	(36)
Drug Release and Dissolution	337	(18)
Biopharmaceutics	355	(42)
Chemical Kinetics and Stability	397	(40)
Dispersed Systems
Interfacial Phenomena	437	(32)
Colloids	469	(30)
Coarse Dispersions	499	(34)
Drug Delivery
Micromeritics	533	(28)
Rheology	561	(24)
Biomaterials	585	(44)
Drug Delivery Systems	629	(52)
Review Problems	681	(80)
Answers to Review Problems	761	(20)
Index	781