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Emphasizing applications of chemistry while reinforcing theory especially in the areas of organic and physical chemistry this new text prepares readers for career success in the pharmaceutical, medical, and biotech industries. Medicinal Chemistry: The Modern Drug Discovery Processdelivers a comprehensive introduction to medicinal chemistry at an appropriate level of detail for a diverse range of readers. By highlighting the concepts and skills related to drug discovery, Stevens deepens readers' understanding of the knowledge and techniques necessary for their careers.
Table of Contents
1 A Brief History of Drug Discovery 2 The Modern Drug Process 3 A Trip through the Body 4 Enzymes as Drug Targets 5 Receptors as Drug Targets 6 Oligonucleotides as Drug Targets 7 Pharmacokinetics 8 Metaboism 9 Molecular Structure and Diversity 10 Lead Discovery 11 Lead Optimization- Traditional Methods 12 Lead Optimization- Hansch Analysis 13 Aspects in Pharmaceutical Synthesis