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Membrane Separations in Biotechnology, Second Edition,,9780824702489
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Membrane Separations in Biotechnology, Second Edition,

by ;
Edition:
2nd
ISBN13:

9780824702489

ISBN10:
0824702484
Format:
Hardcover
Pub. Date:
4/3/2001
Publisher(s):
CRC Press
List Price: $252.00

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Questions About This Book?

What version or edition is this?
This is the 2nd edition with a publication date of 4/3/2001.
What is included with this book?
  • The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any CDs, lab manuals, study guides, etc.

Summary

Covers the practical consideration involved in applying membranes to a range of uses, responding to the latest development in biotechnology. Discusses new and standard membrane technologies, detailing the relationship between membrane technology and bioprocesses. Includes up-to-date cell culture harvesting information.

Author Biography

Jenifer L. Ayala Associate Scientist, CMC and BRD, Berlex Biosciences, Richmond, California Mahmood R. Azari Director of Project Implementation, Recombinant Business Unit/Manufacturing, Hyland Immuno Division, Baxter Healthcare Corporation, Thousand Oaks, California Bernard P. Bautista Process Development Scientist, Process Sciences, Biotechnology Unit, Pharmaceutical Division, Bayer Corporation, Berkeley, California Bruce D. Bowen Department of Chemical and Bio-Resource Engineering, University of British Columbia, Vancouver, British Columbia, Canada Francisco J. Castillo Scientific Director, Fermentation and Cell Culture Development, Berlex Biosciences, Richmond, California G. Michael Connell Senior Associate Process Scientist, Process Sciences, Biotechnology Unit, Pharmaceutical Division, Bayer Corporation, Berkeley, California Alfred C. Dadson Jr. Principal Scientist I, Process Sciences, Biotechnology Unit, Pharmaceutical Division, Bayer Corporation, Berkeley, California Robert H. Davis Pattern Professor, Department of Chemical Engineering, University of Colorado, Boulder, Colorado Igor Yu. Galaev Associate Professor, Department of Biotechnology, Center for Chemistry and Chemical Engineering, Lund University, Lund, Sweden Kent E. Goklen Director, BioProcess Research and Development, Merck Research Laboratories, Rahway, New Jersey Joseph I. Horwitz Fermentation and Cell Culture Development, Berlex Biosciences, Richmond, California Ping Yu Huang Senior Process Engineer, Manufacturing Services, Protein Design Labs, Inc., Fremont, California Brian D. Kelley Associate Director, Purification Process Development, Genetics Institute, Andover, Massachusetts Marek Labecki Department of Chemical and Biological Engineering, The Biotechnology Laboratory, University of British Columbia, Vancouver, British Columbia, Canada Bo Mattiasson Professor, Department of Biotechnology, Center for Chemistry and Chemical Engineering, Lund University, Lund, Sweden W. Courtney McGregor Vice President, Technical Development and Santa Monica Operations, XOMA Corporation, Santa Monica, California Michael Meagher Assistant Professor, Food Science Department, University of Nebraska, Lincoln, Nebraska Gautam Mitra Manufacturing Department, SmithKline Beecham Biologicals, Rixensart, Belgium Harold G. Monbouquette Associate Professor, Chemical Engineering Department, University of California, Los Angeles, California Thomas J. Monica Scientist, Fermentation and Cell Culture Development. Berlex Biosciences, Richmond, California Tana J. Montgomery Associate Scientist, Clinical Production, Berlex Biosciences, Richmond, California Paul K. Ng Principal Research Scientist II, Purification Development, Process Sciences, Biotechnology Unit, Pharmaceutical Division, Bayer Corporation, Berkeley, California Kristen F. Ogle Senior Research Scientist, Renal Division, Baxter Healthcare Corporation, McGaw Park, Illinois John Peterson Associate Scientist, Protein Design Labs, Inc., Fremont, California Jon T. Petrone Principal Engineer, Drug Substance Development, Genetics Institute, Andover, Massachusetts James M. Piret Professor, Department of Chemical and Biological Engineering and Biotechnology Laboratory, University of British Columbia, Vancouver, British Columbia, Canada Georg Roth Senior Scientist, Fermentation and Cell Culture Development, Berlex Biosciences, Richmond, California Gregory Russotti Research Fellow, BioProcess Research and Development, Merck Research Laboratories, Rahway, New Jersey Vicki L. Schlegel Assistant Professor, Food Science Department, University of Nebraska, Lincoln, Nebraska Gary M. Schoofs Clinical Production Manager, Clinical Production, Berlex Biosciences, Richmond, California Peter Schu Director, Vaccines Bulk Manufacturing, Manufacturing Department, SmithKline Beecham Biologicals, Rixensart, Belgium Clayton E. Smith Berlex Biosciences, Richmond, California Robert van Reis Distinguished Engineer, Department of Recovery Sciences, Genentech, Inc., South San Francisco, California William K. Wang Assistant Director, Biopharmaceutical Development, Downstream Process Development, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania Andrew L. Zydney Professor, Department of Chemical Engineering, University of Delaware, Newark, Delaware

Table of Contents

Series Introduction iii
Preface v
Contributors ix
Protein Transport in Ultrafiltration Hollow-Fiber Bioreactors for Mammalian Cell Culture
1(62)
Marek Labecki
Bruce D. Bowen
James M. Piret
Vortex Flow Filtration for Cell Separation in Bioreactor Operations
63(22)
Georg Roth
Clayton E. Smith
Gary M. Schoofs
Tana J. Montgomery
Jenifer L. Ayala
Thomas J. Monica
Francisco J. Castillo
Joseph I. Horwitz
Crossflow Membrane Filtration of Fermentation Broth
85(76)
Gregory Russotti
Kent E. Goklen
Crossflow Microfiltration with Backpulsing
161(28)
Robert H. Davis
Effects of Different Membrane Modular Systems on the Performance of Crossflow Filtration of Pichia pastoris Suspensions
189(16)
Vicki L. Schlegel
Michael Meagher
Filter Applications in Product Recovery Processes
205(20)
Paul K. Ng
Alfred C. Dadson
G. Michael Connell
Bernard P. Bautista
Ultrafiltration Membranes in the Vaccine Industry
225(18)
Peter Schu
Gautam Mitra
Protein Purification by Affinity Ultrafiltration
243(20)
Igor Yu. Galaev
Bo Mattiasson
Process Development for the Isolation of a Recombinant Immunofusion Protein Using a Membrane Adsorber
263(14)
William K. Wang
Harold G. Monbouquette
W. Courtney McGregor
High-Performance Tangential-Flow Filtration
277(22)
Andrew L. Zydney
Robert van Reis
Virus Removal by Ultrafiltration: A Case Study with Diaspirin Crosslinked Hemoglobin (DCLHb)
299(28)
Kristen F. Ogle
Mahmood R. Azari
Scaleup and Virus Clearance Studies on Viral Filtration in Monoclonal Antibody Manufacture
327(24)
Ping Yu Huang
John Peterson
Virus Removal by Tangential-Flow Filtration for Protein Therapeutics
351(46)
Brian D. Kelley
Jon T. Petrone
Index 397


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