Migraine

by Lane; Russell

• ISBN13: 9780824729578
• ISBN10: 0824729579
• Edition: 1st
• Format: Hardcover
• Copyright: 2006-06-02
• Publisher: CRC Press

Summary

Imperial College, London, UK. Focuses on the 'migraine mechanism', its clinical manifestations, and the occasional serious consequences that it can cause. Topics include migraine genes, biological significance of migraine, classification of auras, blackouts, and more. For clinicians. DNLM: Migraine Disorders.

Author Biography

Russell Lane is Consultant Neurologist to the West London Neurosciences Centre at Charing Cross Hospital and Honorary Senior Lecturer in Neurology at Imperial College, London, United Kingdom Paul Davies is Consultant Neurologist and Honorary Senior Lecturer in Neurology at the University of Oxford, Oxford, United Kingdom

Table of Contents

Foreword
Stephen Silberstein	vii
Preface	ix
Landmarks in Migraine	xvii
1. A Brief History of Migraine	1	(40)
"Migraine"—The Etymology of a Clinical Syndrome	1	(7)
Early Descriptions of Auras	8	(5)
Early Concepts of Causality: The 1st to the 16th Century A.D.	13	(1)
The 17th Century: The Influence of Thomas Willis	14	(4)
The 18th and 19th Centuries: Vascular and Neural Hypotheses	18	(7)
The 20th Century	25	(12)
References	37	(4)
2. The Migraine Mechanism	41	(50)
Introduction	41	(1)
What Is Migraine?	42	(3)
Are We All Potential Migraineurs?	45	(1)
The Migraine Mechanism	46	(10)
Headache	56	(10)
Resolution and Postdrome	66	(1)
Migraine Models	67	(4)
How Do Migraines Start?	71	(2)
Why Do Migraines Start?	73	(5)
Migraine Genes	78	(4)
The Biological Significance of Migraine	82	(2)
Conclusion: A Broad Concept of Migraine	84	(1)
References	85	(6)
3. Aura	91	(46)
Introduction	91	(3)
Classification of Auras	94	(30)
"Typical- Auras	94	(17)
Visual Auras	94	(11)
Somesthetic Auras	105	(4)
Dysphasic Auras	109	(2)
"Atypical- Auras	111	(13)
Other Primary Sensory Modalities	111	(2)
Vestibulocochlear Auras	113	(7)
Motor auras	120	(4)
Disorders of Higher Cortical Functions	124	(10)
References	134	(3)
4. Complications	137	(62)
Introduction	137	(1)
Persistent Aura Without Infarction	138	(3)
Migrainous Infarction	141	(35)
Migraine and Blackouts	176	(13)
Migraine Coma	189	(3)
References	192	(7)
5. Variants	199	(60)
Classifying Primary Headaches	199	(2)
Looking Back at "Variants"	201	(2)
The International Headache Society (IHS) Classification of Headache Disorders	203	(1)
Diagnosing Primary Headache Syndromes	204	(12)
Other Primary Headaches	216	(11)
Trigeminal Autonomic Cephalalgias	227	(13)
Symptomatic Migraine	240	(15)
References	255	(4)
6. Conceptualizing Primary Headache	259	(20)
Introduction	259	(1)
How Many Forms of Primary Headache Are There?	260	(17)
What Next?	277	(1)
References	277	(2)
7. Management of Migraine	279	(46)
Introduction	279	(1)
Historical Background	279	(4)
The Burden of Headache	283	(5)
Managing the Headache Patient	288	(5)
Scanning	293	(2)
Myths, Controversies, and Fallacies	295	(3)
The British Association for the Study of Headache Migraine Management (BASH) Guidelines	298	(6)
The Placebo Response and Alternative Medicine in Primary Headache	304	(2)
Treatment of Other Primary Headaches	306	(4)
"Difficult" Headaches	310	(1)
Diagnostic Therapeutic Trials	311	(1)
Surgical Treatments	312	(3)
Headache Treatment—Where Are We Now?	315	(1)
Headache Treatment The Future	315	(2)
Closure of Patent Foramen Ovate	317	(2)
Conclusions	319	(1)
References	320	(5)
Appendix 1. International Headache Society (IHS) Classification (IHC-2)	325	(6)
Appendix 2.	331	(2)
Index	333