Modern Soft Tissue Pathology: Tumors and Non-Neoplastic Conditions

by Edited by Markku Miettinen

• ISBN13: 9780521874090
• ISBN10: 0521874092
• Edition: 1st
• Format: Hardcover
• Copyright: 2010-06-14
• Publisher: Cambridge University Press

Summary

This book comprehensively covers modern soft tissue pathology and includes both tumors and non-neoplastic entities. Soft tissues make up a large bulk of the human body, and they are susceptible to a wide range of diseases. Many soft-tissue tumors are biologically very aggressive, and the chance of them metastasizing to vital organs is quite high. In recent years, the outlook for soft-tissue cancers has brightened dramatically due to the increased accuracy of the pathologist's tools. All methods of diagnosis are covered here, with an emphasis on the newest immunoassays and other genetic, molecular, and immunologic diagnostic modalities. This book's systematic description of benign and malignant primary soft tissue tumors with didactic, comprehensive panels of illustrations allows the reader to formulate a complete understanding of the morphology of tumor entities at one glance. The book covers both the most common tumor entities and more unusual diseases using more than 1,500 color images, making it a resource for beginning and senior pathologists.

Author Biography

Markku Miettinen, MD, PhD, is Chairman and Distinguished Scientist in the Department of Soft Tissue and Orthopedic Pathology, Armed Forces Institute of Pathology, Washington, DC.

Table of Contents

Overview of soft tissue tumors

Radiologic evaluation of soft tissue tumors

Immunohistochemistry of soft tissue tumors

Genetics of soft tissue tumors

Molecular genetics of soft tissue tumors

Fibroblast biology, fasciitis, retroperitoneal fibrosis, and keloid

Fibromas and benign fibrous histiocytomas

Fibromatoses

Benign fibroblastic and myofibroblastic proliferations in children

Childhood fibroblastic and myofibroblastic proliferations of variable biologic potential

Myxomas and ossifying fibromyxoid tumor

Solitary fibrous tumor, hemangiopericytoma, and related tumors

Fibroblastic and myofibroblastic neoplasms with malignant potential

Lipoma variants and conditions simulating lipomatous tumors

Atypical lipomatous tumor and liposarcomas

Smooth muscle tumors

Gastrointestinal stromal tumor

Stromal tumors and tumor-like lesions of the female genital tract

Angiomyolipoma and related tumors (perivascular epithelioid cell tumors, PEComas)

Rhabdomyomas and rhabdomyosarcomas

Hemangiomas, lymphangiomas, and reactive vascular proliferations

Hemangioendotheliomas, angiosarcomas, and Kaposi sarcoma

Glomus tumor, sinonasal hemangiopericytoma, and myopericytoma

Nerve sheath tumors

Neuroectodermal tumors: melanocytic, glial, and meningeal neoplasms

Paragangliomas

Primary soft tumors with epithelial differentiation

Malignant mesothelioma and other mesothelial proliferations

Merkel cell carcinoma and metastatic and sarcomatoid carcinomas involving soft tissues

Cartilage and bone-forming tumors and tumor-like lesions

Small round cell tumors

Alveolar soft part sarcoma

Pathology of synovial and tendons

Miscellaneous tumor-like lesions and histiocytic and foreign body reactions

Lymphatic, myeloid, histiocytic, and dendritic cell proliferations in soft tissues

Cytology of soft tissue lesions

Surgical management of soft-tissue sarcoma: histiologic type and grade guides, surgical planning, and integration of multimodality therapy

Medical oncology of soft tissue sarcomas

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