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Written and illustrated with unsurpassed clarity, Molecular Biology: Principles and Practice introduces fundamental concepts while exposing students to how science is done. The authors convey the sense of joy and excitement that comes from scientific discovery, highlighting the work of researchers who have shaped—and who continue to shape—the field today.
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Table of Contents
I. Foundations1. Evolution, Science, and Molecular Biology2. DNA: The Repository of Biological Information3. Chemical Basis of Information Molecules4. Protein Structure5. Protein FunctionII. Nucleic Acid Structure and Methods6. DNA and RNA Structure7. Studying Genes8. Genomes, Transcriptomes, and Proteomes9. Topology: Functional Deformations of DNA10. Nucleosomes, Chromatin, and Chromosome Structure III. Information Transfer11. DNA Replication12. DNA Mutation and Repair13. Recombinational DNA Repair and Homologous Recombination14. Site-Specific Recombination and Transposition15. Transcription: DNA-Dependent Synthesis of RNA16. RNA Processing17. The Genetic Code18. Protein SynthesisIV. Regulation19. Regulating the Flow of Information20. The Regulation of Gene Expression in Bacteria21. The Transcriptional Regulation of Gene Expression in Eukaryotes22. The Posttranscriptional Regulation of Gene Expression in EukaryotesAppendix: Model Organisms GlossarySolutions to ProblemsIndex