Natural Products in Chemical Biology

by Civjan, Natanya

• ISBN13: 9781118101179
• ISBN10: 1118101170
• Edition: 1st
• Format: Hardcover
• Copyright: 2012-07-03
• Publisher: Wiley

Summary

Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as "natural products", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.

Author Biography

Natanya Civjan, Phd, is a freelance editor with a doctorate in biochemistry. Formerly with John Wiley Sons, she has developed and edited the Wiley Encyclopedia of Chemical Biology and was part of the team responsible for the Wiley Interdisciplinary Reviews, which won top prizes in publishing from the American Publishers Awards for Professional and Scholarly Excellence.

Table of Contents

Preface	p. vii
Contributors	p. ix
Chemical Diversity of Natural Products	p. 1
Plant Natural Products	p. 3
Marine Natural Products	p. 31
Microbial Natural Products	p. 65
Biosynthesis of Natural Products	p. 109
Nonribosomal Peptides	p. 111
Plant Terpenoids	p. 127
Polyketides in Fungi	p. 143
Modular Polyketide Synthases	p. 163
Polyketide Polyethers	p. 189
Alkaloids	p. 209
Cofactors	p. 239
Antibiotics	p. 269
Natural Products in Medicine	p. 287
Pharmaceuticals: Natural Products and Natural Product Models	p. 289
Natural Products as Anticancer Agents	p. 325
Plant-Derived Natural Products Research in Drug Discovery	p. 351
Index	p. 389
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